Publications by authors named "Peng-Yu Zhao"

Background: Renal ischemia reperfusion (I/R) injury is a major contributor to graft dysfunction and inflammation leading to graft loss. The deregulation of purinergic signaling has been implicated in the pathogenesis of renal I/R injury. CD73 and the generation of adenosine during purine metabolism to protect against renal I/R injury.

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Background: The application of nanomedicine in inflammatory bowel disease (IBD) has gained significant attention in the recent years. As the field rapidly evolves, analyzing research trends and identifying research hotpots are essential for guiding future advancements, and a comprehensive bibliometric can provide valuable insights.

Methods: The current research focused on publications from 2001 to 2024, and was sourced from the Web of Science Core Collection (WoSCC).

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This study investigated the effects of quercetagetin (QG) on growth performance, nutrient digestibility, meat quality, and antioxidant capacity of broilers. Four hundred 1-day-old Cobb broilers were randomly divided into five diets, each with eight replicates and 10 birds per replicate. The diets included a basal diet, and four diets with 25, 50, 100, and 200 mg/kg QG supplemented in basal diet.

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  • Exosomes derived from endometrial regenerative cells (ERC-Exos) have potential immunomodulatory effects, particularly in treating inflammatory bowel diseases like colitis, and the role of insulin-like growth factor-Ⅱ (IGF2) in this process was explored.
  • In experiments with mice experiencing colitis, treatment with ERC-Exos led to significant improvements in symptoms and intestinal health compared to untreated mice, but the protective effects were reduced when IGF2 was knocked out from the exosomes.
  • Additionally, the presence of IGF2 in ERC-Exos was found to influence immune cell populations, reducing harmful T helper cell types and dendritic cell activity, suggesting a beneficial immunological shift towards a more anti-inflammatory environment
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  • Autoimmune enteropathy (AIE) is a rare and challenging disease to diagnose and manage in adults, with a study analyzing 16 cases over 12 years to better understand its characteristics and prognosis.
  • The study found common symptoms like secretory diarrhea, significant endoscopic findings (like edema and villous blunting), and specific histopathological changes such as reduced goblet and Paneth cells in biopsies.
  • While most patients initially responded to glucocorticoid therapy, the prognosis varied, with 62.5% relapse-free survival after 6 months, and some patients facing serious complications, including death and lymphoma diagnosis.
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Background: Eosinophilic gastroenteritis (EGE) is a chronic recurrent disease with abnormal eosinophilic infiltration in the gastrointestinal tract. Glucocorticoids remain the most common treatment method. However, disease relapse and glucocorticoid dependence remain notable problems.

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To clarify the content characteristics of the main active components and mineral elements of Cynomorium songaricum under different habitat conditions, and further explore the relationship between the quality of C. songaricum and habitats, this study took C. songaricum from 25 different habitats in China as the research object, and measured the contents of 8 main active components and 12 mineral elements separately.

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can cause liver abscess, foot rot in ruminants, and Lemire syndrome in humans, Also, its virulence factors can induce the apoptosis of macrophages and neutrophils. However, the detailed mechanism has not been fully clarified. This study investigated the mechanisms of apoptosis and inflammatory factor production in -induced neutrophils and macrophages (RAW246.

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Objective To investigate the suitable services of telemedicine at present and the future from the perspective of medical service supplier,clarify the challenges in the development of telemedicine services at present,and provide evidence-based suggestions for improving the quality of telemedicine services. Methods A questionnaire was developed through literature review for the survey of telemedicine services from the perspective of service providers.From January to June in 2020,electronic questionnaires were collected from volunteers.

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Human activities and climate change cause the degradation of subalpine lake ecosystems, which induce the shift of microbial community structure. The spatio-temporal dynamics and the diversity maintenance mechanisms of bacterial communities in Gonghai Lake in Ningwu, Shanxi, were investigated by using Q-PCR and DGGE. The results showed that the temperature), pH, dissolved oxygen, electrical conductivity salinity, and ammonium nitrogen (NH) contestation were significantly different among the different sampling depths during different months.

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The community assembly process, which purports that the trade-off between the stochastic process and the deterministic process, is the central issue of community ecology, and is one of the most controversial ecological issues. The current research investigated the fungal community in the forests of the Guandi Mountains and elucidated the relative role of the stochastic and deterministic processes in the assembly of soil fungal community on a local scale. The correlation analysis and redundancy analysis of the physicochemical factors in soil and dominant fungal phyla, as well as the structural equation model analysis, showed that these physicochemical factors and aboveground vegetation diversity had significant effects on fungal communities.

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Objective: To in vestigate potential gender differences in the odds of overweight/obese, weight-related perceptions, and behaviors among Chinese school children.

Methods: Height, weight, and a survey of weight-related perceptions and behaviors were measured in a nationally representative survey of 12,811 children in primary schools in China. Logistic regression analyses were used to assess gender differences, adjusting for confounders.

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