Accuracy Testing of Torque Limit Determination Algorithm Intended for Smart Bone Screwdrivers.

Bone screws are used in orthopaedic surgery for fracture fixation. Correctly torquing the screws is important for fixation quality. Over-tightening may strip the threads, while under-tightening may result in loosening over time.

Tidal Volume Monitoring via Surface Motions of the Upper Body-A Pilot Study of an Artificial Intelligence Approach.

The measurement of tidal volumes via respiratory-induced surface movements of the upper body has been an objective in medical diagnostics for decades, but a real breakthrough has not yet been achieved. The improvement of measurement technology through new, improved sensor systems and the use of artificial intelligence have given this field of research a new dynamic in recent years and opened up new possibilities. Based on the measurement from a motion capture system, the respiration-induced surface motions of 16 test subjects were examined, and specific motion parameters were calculated.

What do users in a polycystic ovary syndrome (PCOS) forum think about the treatments they tried: Analysing treatment sentiment using machine learning.

Polycystic ovary syndrome (PCOS) is a heterogenous condition that is estimated to effect up to 21% of reproductive aged people with ovaries. In previous work, a dataset of PCOS features was derived from approximately 100,000 PCOS subreddit users via machine learning. In this study, an exploration of treatment response within the PCOS subreddit was undertaken with the derived dataset.

The influence of cooling on biomechanical time since death estimations using ovine brain tissue.

The significance of biomechanical analyses for forensic time since death estimations has recently been demonstrated. Previous biomechanical analyses successfully discriminated post-mortem brain tissue from tissue with a post-mortem interval of at least one day when held at 20 °C. However, the practical utility of such analyses beyond day one at 20 °C was limited.

Evolving Improved Sampling Protocols for Dose-Response Modelling Using Genetic Algorithms with a Profile-Likelihood Metric.

Practical limitations of quality and quantity of data can limit the precision of parameter identification in mathematical models. Model-based experimental design approaches have been developed to minimise parameter uncertainty, but the majority of these approaches have relied on first-order approximations of model sensitivity at a local point in parameter space. Practical identifiability approaches such as profile-likelihood have shown potential for quantifying parameter uncertainty beyond linear approximations.

A Novel Experimental Approach for the Measurement of Vibration-Induced Changes in the Rheological Properties of Ex Vivo Ovine Brain Tissue.

Increased incidence of traumatic brain injury (TBI) imposes a growing need to understand the pathology of brain trauma. A correlation between the incidence of multiple brain traumas and rates of behavioural and cognitive deficiencies has been identified amongst people that experienced multiple TBI events. Mechanically, repetitive TBIs may affect brain tissue in a similar way to cyclic loading.

Analysis of Flow Through Extra-Anatomic Bypasses Between Supra-Aortic Branches Using Particle Image Velocimetry (PIV).

Supra-aortic extra-anatomic debranch (SAD) are prosthetic surgical grafts used to revascularize head and neck arteries that would be blocked during a surgical or hybrid procedure used in treating ascending and arch of the aorta pathologies. However, bypassing the supra-aortic arteries but not occluding their orifice might introduce potential for competitive flow that reduces bypass patency. Competitive flow within the bypasses across the supra-aortic arteries has not previously been identified.

Sensor Selection for Tidal Volume Determination via Linear Regression-Impact of Lasso versus Ridge Regression.

The measurement of respiratory volume based on upper body movements by means of a smart shirt is increasingly requested in medical applications. This research used upper body surface motions obtained by a motion capture system, and two regression methods to determine the optimal selection and placement of sensors on a smart shirt to recover respiratory parameters from benchmark spirometry values. The results of the two regression methods (Ridge regression and the least absolute shrinkage and selection operator (Lasso)) were compared.

Comparing Literature- and Subreddit-Derived Laboratory Values in Polycystic Ovary Syndrome (PCOS): Validation of Clinical Data Posted on PCOS Reddit Forums.

Background: Polycystic ovary syndrome (PCOS) is a heterogeneous condition that affects 4% to 21% of people with ovaries. Inaccessibility or dissatisfaction with clinical treatment for PCOS has led to some individuals with the condition discussing their experiences in specialized web-based forums.

Objective: This study explores the feasibility of using such web-based forums for clinical research purposes by gathering and analyzing laboratory test results posted in an active PCOS forum, specifically the PCOS subreddit hosted on Reddit.

Laparoscopic Video Analysis Using Temporal, Attention, and Multi-Feature Fusion Based-Approaches.

Adapting intelligent context-aware systems (CAS) to future operating rooms (OR) aims to improve situational awareness and provide surgical decision support systems to medical teams. CAS analyzes data streams from available devices during surgery and communicates real-time knowledge to clinicians. Indeed, recent advances in computer vision and machine learning, particularly deep learning, paved the way for extensive research to develop CAS.

Characterisation and Quantification of Upper Body Surface Motions for Tidal Volume Determination in Lung-Healthy Individuals.

Measurement of accurate tidal volumes based on respiration-induced surface movements of the upper body would be valuable in clinical and sports monitoring applications, but most current methods lack the precision, ease of use, or cost effectiveness required for wide-scale uptake. In this paper, the theoretical ability of different sensors, such as inertial measurement units, strain gauges, or circumference measurement devices to determine tidal volumes were investigated, scrutinised and evaluated. Sixteen subjects performed different breathing patterns of different tidal volumes, while using a motion capture system to record surface motions and a spirometer as a reference to obtain tidal volumes.

Development of a Head Acceleration Event Classification Algorithm for Female Rugby Union.

Instrumented mouthguards have been used to detect head accelerations and record kinematic data in numerous sports. Each recording requires validation through time-consuming video verification. Classification algorithms have been posed to automatically categorise head acceleration events and spurious events.

Analysing multi-perspective patient-related data during laparoscopic gynaecology procedures.

Fusing data from different medical perspectives inside the operating room (OR) sets the stage for developing intelligent context-aware systems. These systems aim to promote better awareness inside the OR by keeping every medical team well informed about the work of other teams and thus mitigate conflicts resulting from different targets. In this research, a descriptive analysis of data collected from anaesthesiology and surgery was performed to investigate the relationships between the intra-abdominal pressure (IAP) and lung mechanics for patients during laparoscopic procedures.

Particle Image Velocimetry Evaluation of Hemodynamics Proximal to the Kissing Stent Configuration in the Aorto-Iliac Bifurcation.

Purpose: The kissing stent (KS) method is low-risk compared with open surgery techniques. It is often used to treat aorto-iliac occlusive disease (AIOD). Deployment of the KS geometry has a high technical success rate.

A review of the hormones involved in the endocrine dysfunctions of polycystic ovary syndrome and their interactions.

Polycystic ovary syndrome (PCOS) affects up to 20% of women but remains poorly understood. It is a heterogeneous condition with many potential comorbidities. This review offers an overview of the dysregulation of the reproductive and metabolic systems associated with PCOS.

Quantifying Accuracy of Self-Tapping Screw Models.

Correct torquing of bone screws is important to prevent fixation failures and ensure positive patient outcomes. It has been proposed that an automatic model-based method may be able to determine the patient-specific material properties of bone, and provide objective and quantitative torquing recommendations. Models have been previously proposed for identifying the bone material properties, but have not been experimentally tested for accuracy.

Geometric Generalization of Self Tapping Screw Insertion Model.

Bone screws are used in orthopaedic procedures to fix implants and stabilise fractures. These procedures require care, as improperly torquing the screws can lead to implant failure or tissue damage, potentially requiring revision surgery or causing further disability. It was proposed that automated torque-limit identification may allow clinical decision support to control the screw torque, and lead to improved patient outcomes.

Investigating Torque-Speed Relationship of Self-Tapping Screws.

Correctly torquing bone screws is important to prevent fixation failures and ensure positive patient outcomes. It has been proposed that an automatic model-based method may be able to determine the patient-specific material properties of bone, and provide objective and quantitative torquing recommendations. One major part of developing this system is the modelling of the bone-screwing process, and the self-tapping screwing process in general.

Review of the Development of Hemodynamic Modeling Techniques to Capture Flow Behavior in Arteries Affected by Aneurysm, Atherosclerosis, and Stenting.

Cardiovascular diseases (CVDs) are the leading cause of death in the developed world. CVD can include atherosclerosis, aneurysm, dissection, or occlusion of the main arteries. Many CVDs are caused by unhealthy hemodynamics.

In vitro pulsatile flow study in compliant and rigid ascending aorta phantoms by stereo particle image velocimetry.

The aorta is a high risk region for cardiovascular disease (CVD). Haemodynamic patterns leading to CVD are not well established despite numerous experimental and numerical studies. Most overlook effects of arterial compliance and pulsatile flow.

Frequency and duration of ambulance officer exposure to nitrous oxide and methoxyflurane in New Zealand.

Objective: Nitrous oxide (Entonox) and methoxyflurane (Penthrox) are inhaled analgesics administered in paramedicine. Occupational exposure to nitrous oxide has been associated with negative health effects, and may inhibit professional capability. The effect of occupational exposure to methoxyflurane has not yet been clearly determined.

The Effects of Additional Local-Mixing Compartments in the DISST Model-Based Assessment of Insulin Sensitivity.

Background: The identification of insulin sensitivity in glycemic modelling can be heavily obstructed by the presence of outlying data or unmodelled effects. The effect of data indicative of local mixing is especially problematic with models assuming rapid mixing of compartments. Methods such as manual removal of data and outlier detection methods have been used to improve parameter ID in these cases, but modelling data with more compartments is another potential approach.

Serum fluoride levels in ambulance staff after commencement of methoxyflurane administration compared to meta-analysis results for the general public.

Objectives: Ambulance officers administering methoxyflurane as an inhalational analgesic may be exposed to trace vapor. Fluoride is a methoxyflurane metabolite, and has been associated with acute renal failure in anesthesia patients and skeletal fluorosis with chronic elevated serum levels from other sources. However, there has been no direct measurement of serum fluoride in occupationally exposed ambulance officers.

Methoxyflurane toxicity: historical determination and lessons for modern patient and occupational exposure.

Aim: Historically methoxyflurane was used for anaesthesia. Evidence of nephrotoxicity led to abandonment of this application. Subsequently, methoxyflurane, in lower doses, has re-emerged as an analgesic agent, typically used via the Penthrox inhaler in the ambulance setting.

PIV Analysis of Haemodynamics Distal to the Frozen Elephant Trunk Stent Surrogate.

Purpose: The Frozen Elephant Trunk (FET) stent is a hybrid endovascular device that may be implemented in the event of an aneurysm or aortic dissection of the aortic arch or superior descending aorta. A Type 1B endoleak can lead to intrasaccular flow during systole and has been identified as a known failure of the FET stent graft. The purpose was to develop in-vitro modelling techniques to enable the investigation of the known failure.