Management of Glomus Tumors: Experience From a Tertiary Care Centre in India.

Background: Glomus tumors are uncommon soft tissue tumors that typically develop in the distal extremities, especially the finger's subungual area. Pain, soreness, and temperature intolerance, particularly cold sensitivity, make up its traditional clinical triad. There is a relative rarity in the literature on this topic, and we have analyzed and thereby discussed our experience in these cases.

Expression of inflammatory proteins STAT & NFĸB for phenotypic diagnosis of gall bladder cancer: A pilot study.

Background & objectives Gallbladder cancer (GBC) has a low overall survival rate due to late detection and poor prognosis. Chronic inflammation contributes to malignant conversion and metastasis in GBC. Expression of inflammatory proteins, such as signal transducer and activator of transcription factor (STAT) and nuclear factor kappa B (NFĸB) proteins, for diagnosis through immunohistochemistry (IHC) is a promising area of research; however, diagnosis of GBC through IHC-based methods is still in its infancy.

Artificial intelligence and robotics in regional anesthesia.

Artificial intelligence (AI) technology is vital for practitioners to incorporate AI and robotics in day-to-day regional anesthesia practice. Recent literature is encouraging on its applications in regional anesthesia, but the data are limited. AI can help us identify and guide the needle tip precisely to the location.

Prediabetes in children and adolescents: A ticking bomb!

Prediabetes in children and adolescents is on the rise which has drawn significant attention over the past decade. It is an early warning sign of the underlying pathophysiological changes which in due course of time might compound into type II diabetes mellitus. The incidence of prediabetes in adolescents ranges from 4%-23% which is alarmingly high and requires active intervention from the system.

Bilirubin in wound healing: A double-edged sword.

The impact of bilirubin levels on wound healing remains a topic of controversy. The present study is a literature review that examines the impact of increased levels of bilirubin in the bloodstream on the process of wound healing. The physiological pathways and their interrelationships, as well as the relevant research publications, were comprehensively addressed in our discussion.

Deliberating a Re(n)al-world Research Setting.

Choudhary N, Magoon R, Jose J. Deliberating a Re(n)al-world Research Setting. Indian J Crit Care Med 2023;27(4):297.

Ketodex for MRI sedation in syndromic children with congenital cardiac anomalies - A case series.

Safe paediatric sedation in a magnetic resonance imaging (MRI) suite can be challenging. The challenges intensify in uncooperative syndromic children compounded by an accentuated risk of periprocedural cardio-respiratory complications with anaesthetic sedation in this peculiarly predisposed subset. Amidst ardent debates on the ideal sedative agent for paediatric MRI, we report an encouraging application of ketamine-dexmedetomidine combination (ketodex) sedation for MRI in our case-series including syndromic children with coexistent congenital cardiac anomalies.

Fibrinolysis and D-dimer in COVID-19: A Twisted Plot!

Unlabelled: Coronavirus disease-2019 (COVID-19) and the associated pathophysiological perturbations continue to bewilder the fraternity at large. In this context, the thromboembolic predisposition in COVID-19 has particularly emerged as a matter of an ardent debate. The index commentary aims to present an account of the recent developments in the understanding of the immunothrombosis in the enigmatical setting of COVID-19.

Self-Rolled-Up Aluminum Nitride-Based 3D Architectures Enabled by Record-High Differential Stress.

Aluminum nitride (AlN) continues to kindle considerable interest in various microelectromechanical system (MEMS)-related fields because of its superior optical, mechanical, thermal, and piezoelectric properties. In this study, we use magnetron sputtering to tailor intrinsic stress in AlN thin films from highly compressive (-1200 MPa) to highly tensile (+700 MPa), with a differential stress of 1900 MPa. By monolithically combining the compressive and tensile ultrathin AlN bilayer membranes (20-60 nm) during deposition, perfectly curved three-dimensional (3D) architectures are spontaneously formed upon dry-releasing from the substrate via a 3D MEMS approach: the complementary metal-oxide-semiconductor (CMOS)-compatible strain-induced self-rolled-up membrane (S-RuM) method.

Comparative evaluation of dexmedetomidine and fentanyl in total intravenous anesthesia for laparoscopic cholecystectomy: A randomised controlled study.

Background And Aims: Laparoscopic cholecystectomy is one of the commonly performed ambulatory surgeries. The selection of anesthetic agents for ambulatory surgeries should be done bearing in mind the need for early discharge. Opioids form an integral component of total intravenous anesthesia (TIVA) but their associated side effects may result in an increased hospital stay.

The role of magnesium in perioperative management of intracranial aneurysm surgery: A case series.

As the motivation to potentially allow for a more expansive role of opioid-sparing anaesthesia in various surgical specialities transpire with new zeal, promising evidence needs to be accumulated to substantiate the same. Appropriate to this context, the index case series highlight the beneficial effects of an intraoperative magnesium sulphate infusion on perioperative hemodynamic profile and postoperative recovery in patients undergoing intracranial cerebral aneurysm surgery.