A Case Report of A Rare Giant Parotid Pleomorphic Adenoma with Atypical Preoperative Cytological Presentation of Category-IVB SUMP.

Giant pleomorphic adenomas of the parotid gland are rare, particularly in younger patients, and their preoperative cytological evaluation can be challenging. The Milan System for Reporting Salivary Gland Cytopathology (MILAN) provides a framework for categorizing salivary gland lesions, but atypical presentations complicate diagnosis. A 31 year-old female presented with a large parotid mass, clinically suggestive of a giant pleomorphic adenoma.

Flow Cytometric DNA Ploidy Analysis in Haemato-Lymphoid Neoplasms: An Analysis of 132 Cases.

FxCycle Violet (FCV) based flow cytometric (FCM) DNA ploidy analysis is a rapid and simple tool that can substantiate in characterizing the biological behaviour across the spectrum of haematological malignancies and correlates with cytogenetic studies. In this prospective study, we performed simultaneous immunophenotyping with FCV based on ploidy analysis in n=132 consecutive new samples, comprising n=110 samples of haemato-lymphoid neoplasms, including acute leukemias (n=67, 60.9%), CML with myeloid blast crisis (n=1, 0.

Hodgkin Variant of Richter's Transformation in Chronic Lymphocytic Leukemia (CLL): An Illustrative Case Report and Literature Review.

Hodgkin lymphoma variant of Richter's transformation (HL-RT) is a rare event, occurring in < 1% chronic lymphocytic leukemia (CLL) cases, of which, in < 10% cases, HL is the first finding leading to a diagnosis of CLL that co-exists simultaneously. Here we report a 60 years old male patient who presented with an outside diagnosis of lymphocyte-rich classical HL. On evaluation, he had only B-symptoms in the form of low-grade fever and weight loss.

Spectrum and Immunophenotypic Profile of Acute Leukemia: A Tertiary Center Flow Cytometry Experience.

Background: For diagnosis, sub-categorization and follow up of Acute Leukemia (AL), phenotypic analysis using flow cytometry is mandatory.

Material And Methods: We retrospectively analyzed immunophenotypic data along with cytogenetics/molecular genetics data (wherever available) from 631 consecutive cases of AL diagnosed at our flow cytometry laboratory from January 2014 to August 2017.

Results: Of the total 631 cases, 52.

FxCycle™ Based Ploidy Correlates with Cytogenetic Ploidy in B-Cell Acute Lymphoblastic Leukemia and Is Able to Detect the Aneuploid Minimal Residual Disease Clone.

Background: Flow cytometry (FCM) is a simple, sensitive, and specific technique that can potentially determine DNA ploidy in B-cell precursor ALL (BCP-ALL) and is complementary to cytogenetics.

Methods: A prospective FCM DNA ploidy analysis using FxCycle™ Violet (assay sensitivity 0.01%) was done in 125 consecutive new cases of BCP-ALL (90 cases <15 years of age) and compared with corresponding cytogenetic ploidy (karyotyping and/or FISH) data wherever available.

Evaluation of Various Laryngeal Pathologies: Videolaryngoscopy Versus Videolaryngostroboscopy.

Voice disorders are common in various laryngeal pathologies. The aim of this study is to evaluate the diagnostic value of videolaryngostroboscopy (VLSS) over videolaryngoscopy (VLS) in laryngeal pathologies. This was a prospective observational study.

Steroid Cell Tumour of Ovary - A Rare Case Report.

Steroid cell tumours of the ovary are uncommon sex- hormone secreting tumours characterized by a steroid cell proliferation. The incidence of steroid cell tumour of the ovary is only 0.1% of all ovarian tumours.

Prevalence and clinical significance of IgA anti-tissue transglutaminase antibodies in patients with chronic liver disease.

Background And Aim: Celiac disease is a multi-systemic disease, which can affect any organ system including liver. However, the prevalence of celiac disease and the sensitivity and specificity of anti-tissue transglutaminase (anti-tTG) in diagnosing celiac disease in patients with cirrhosis of liver is not well established.

Methods: We screened a cohort of patients with chronic liver disease for an associated diagnosis of celiac disease.

Correlation between Sex Chromatin and Female Breast Tumour in Paraffin Sections, Buccal Smears and Peripheral Blood Films.

Introduction: Sex chromatin is a plano-convex to triangular DNA mass measuring approximately 1μm in size and lying adjacent to the inner side of nuclear membrane in the somatic cells of the females. There is consistent loss in the sex chromatin percentage in the carcinoma cases in comparison to benign lesions and normal individuals.

Aim: To know the correlation between the sex chromatin status in female breast tumors on paraffin sections, buccal smears and peripheral blood films.

Effect of glare on night time driving in alcoholic versus non-alcoholic professional drivers.

Context: The use of alcohol during nighttime driving may affect recovery from glare leading to increased traffic accidents.

Objective: To compare the glare recovery time in alcoholic versus non-alcoholic drivers.

Materials And Methods: Alcoholic (n = 25) and non-alcoholic drivers (n = 25) were subjected to glare recovery test and they also filled a questionnaire about the nighttime driving.