Publications by authors named "Bal Manjit Singh"
Association between Microrna 146a and Microrna 196a2 Genes Polymorphism and Breast Cancer Risk in North Indian Women.
Asian Pac J Cancer Prev
September 2017
Background: Micro RNAs (miRNAs) are small, noncoding RNA molecules. They can function as either oncogenes or tumor suppressor genes. Single nucleotide polymorphisms (SNP) present in the pre-miRNA region could affect the processing of miRNA and thus alter mature miRNA expression.
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- Punjab has been identified as a region with a perceived high incidence of cancer, particularly in the Malwa Region, partly due to population growth and increased health reporting.
- A study analyzed data from 500 cancer patients registered with the Mukh Mantri Punjab Cancer Rahat Kosh Scheme at Rajindra Hospital Patiala, revealing that 65% of patients were female, with breast cancer being the most common in women and colon cancer in men.
- Common cancer types included adenocarcinoma and squamous cell carcinoma, highlighting an urgent need for better cancer prevention, treatment, and planning in Punjab.
Introduction: Sex chromatin is a plano-convex to triangular DNA mass measuring approximately 1μm in size and lying adjacent to the inner side of nuclear membrane in the somatic cells of the females. There is consistent loss in the sex chromatin percentage in the carcinoma cases in comparison to benign lesions and normal individuals.
Aim: To know the correlation between the sex chromatin status in female breast tumors on paraffin sections, buccal smears and peripheral blood films.
A 50-year old female presented with the chief complaint of a discharge per vaginum, which was there for the past 15 days. A routine PAP smear was received in the Department of Pathology, Government Medical College, Patiala, India. After its fixation and staining, it was examined under the microscope.
View Article and Find Full Text PDFBackground: Cervical cytology by Papanicolaou (Pap) smears is an effective means of screening for cervical premalignant and malignant conditions. Cervical intra-epithelial neoplasia (CIN) and cervical cancer remain important health problems for women worldwide.
Aim: To study the role of Pap smear in detecting premalignant and malignant lesions of cervix; and to determine the prevalence of various lesions.
Solitary schwannomas constitute only 2%-6% of stromal tumors of the gastrointestinal tract; the stomach is the preferred site of involvement. We report a 35-year-old woman who presented with difficulty in defecation. A mass on the posterior wall of the rectum was excised.
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