Compact wideband implantable antenna for wireless capsule endoscopy application in the 2.45 GHz ISM band.

This paper presents a compact wideband implantable antenna developed for wireless capsule endoscopy (WCE) functioning in the 2.4-2.48 GHz ISM band.

Socio-Demographic Profile of Low Back Pain in Health Care Workers of a Tertiary Care Center of Eastern India - A Cross-Sectional Study.

Background And Aim: Majority of the healthcare workers (HCWs) globally have low back pain (LBP) at some point of time of their lives, resulting in activity limitation and sick leave. HCWs are exposed to the burden of long duty hours, poor posture, inadequate sleep hours, stress, etc., which ultimately leads to the occurrence of LBP.

Demographic and Clinical Profiles of Parkinson's Disease in India: Observations from a Nation-Wide Multicenter Study.

Background: Parkinson's disease (PD) phenotype may vary with genetic, ethno-geographic, cultural, and environmental factors.

Objectives: The aim was to develop a clinical database of PD in India and assess the influence of age-at-onset (AAO), gender, and motor subtype on the clinical profile of PD.

Methods: A cross-sectional study of PD was conducted across 18 Indian hospitals.

Direct oral anticoagulants versus vitamin K antagonists in concurrent hypertrophic cardiomyopathy and atrial fibrillation: a meta-analysis.

Introduction: Twenty to twenty-five percent of patients with hypertrophic cardiomyopathy (HCM) have concurrent atrial fibrillation (AF). It is unclear whether direct oral anticoagulants (DOAC) are a safe and effective alternative to vitamin K antagonists (VKA) in concurrent HCM and AF.

Methods: We performed a systematic review and meta-analysis of original reports comparing DOACs versus VKAs in concurrent HCM and AF.

Vitamin B Therapy, Methionine Synthase and Cystathionine Beta-Synthase (CBS) Gene Polymorphisms, and Their Impact on Homocysteine and Cardiovascular Events in Ischemic Stroke With Normal Renal Function: A Randomized Controlled Trial.

Background: Hyperhomocysteinemia cases were found to be higher in hilly regions due to factors such as high altitude and dehydration. There is limited research on methionine synthase (MS) and cystathionine beta-synthase (CBS) gene polymorphisms among stroke patients in Southeast Asia. The primary objective of the study was to determine the efficacy of vitamin B therapy in lowering homocysteine levels, and the secondary objective was to investigate the prevalence and impact of MS and CBS gene polymorphisms on treatment outcomes and cardiovascular events.

Circulating urobilinogen augments inflammation and corticosteroid non-response in severe alcohol-induced hepatitis.

Severe alcohol-associated hepatitis (SAH) is a life-threatening condition with high mortality rates and poor response to prednisolone therapy. Identifying reliable early predictors of therapy response and survival is critical. Plasma metabolomics was conducted on 70 SAH patients (50 responders and 20 non-responders) to identify biomarkers for non-response and early mortality.

Anti-Cancer Role of Ellagic Acid by Modulating the Altered PI3K/PTEN/Akt Pathway in Bladder Cancer.

Bladder cancer (BCa) is approximately the fourth most prevalent diagnosed cancer in men and is three times less common in women. Therefore, identifying biomarkers, developing more effective therapeutic strategies, and understanding the mechanisms underlying BCa tumor growth and progression are urgently required to improve survival rates. Therefore, we aim to investigate the expression of PTEN/Akt in tissue samples of both non-muscle invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) patients (n = 70) and human BCa cell lines T24 and 5637, along with the potent role of ellagic acid (EA) in the modulation of the PTEN/Akt pathway and the resulting therapeutic potential.

Food loss and waste management in the retail food supply chain: Methods and framework to achieve environmental sustainability.

Food loss and waste (FLW) represents critical challenge to environmentally sustainable development, impacting food security, waste management, and climate change. One-third of the world's food is disposed of, with 13 % lost between harvest and the supply chain and 17 % wasted domestically and in food services. Food loss and waste (FLW) in retail supply chains is a critical issue demanding new frameworks due to its significant economic, social, and environmental impacts, including pollution, resource depletion, and climate change contributions.

Impact of patient gender on surgical outcomes of infective endocarditis in adults: a systematic review and meta-analysis protocol.

Introduction: Infective endocarditis is a rare but severe disease affecting 3-10 per 100 000 each year associated with a mortality of 25%. However, it is thought to affect females more severely than men, despite lower incidence. However, reasons for this are unknown, and there is controversy surrounding evidence for differences in surgical outcomes for infective endocarditis.

Development and validation of Restless Legs Syndrome Diary for the assessment of severity and course of symptoms - A cross-sectional study.

Background: The clinical course and severity of restless legs syndrome (RLS) are variable. Existing questionnaires measure the severity of RLS based on recall. One possible solution could be the daily charting of symptoms in a diary.

Effect of Ketamine Analgosedation on Neurological Outcome in patients with Severe Traumatic Brain Injury: A Randomized Controlled Pilot Study.

Background: Most of the sedative and analgesic drugs used in patients with head injury cause a dose-dependent decrease in blood pressure, which may further worsen secondary neurologic injury. The sympathomimetic profile of ketamine, along with its neuroprotectant effect, can have a beneficial effect in these patients.

Methods: A total of 60 adult patients with severe traumatic brain injury were randomized to receive either ketamine infusion at 3 mg/kg/h or normal saline.

Transaneurysmal Suturing of Pseudoaneurysm Neck: Novel and Not a Pseudo-Technique for Treatment of Complicated Femoral Pseudoaneurysm.

 Femoral pseudoaneurysm is one of the common complications following femoral artery catheterization. It poses a significant morbidity and a nonsurgical technique with the utmost low complication risk is warranted. Various methods have been used to treat these pseudoaneurysms including manual compression, ultrasound-guided compression, and percutaneous injection of thrombin or glue.

Clinical epidemiology of young men with lower urinary tract symptoms: The SciCOM 3 project.

Introduction: A study was performed to determine the most common and most bothersome symptoms and clinical associations in young men (18-40 years) presenting with lower urinary tract symptoms (LUTS).

Methods: Cross-sectional study was conducted across 16 centers. Urinary symptoms, impact of bladder problems, bowel symptoms, erectile dysfunction, premature ejaculation, bladder pain, non-bladder myofascial pain, and general well-being were assessed by validated questionnaires.

Transarterial Chemoembolization: A Consistent and Continuously Evolving Therapy for Hepatocellular Carcinoma.

Since its introduction in 1977, transarterial chemoembolization (TACE) has widely been accepted treatment for unresectable intermediate stage hepatocellular carcinoma (HCC). Conventional TACE (c-TACE) uses an emulsion of chemotherapeutic agent and ethiodized oil with subsequent embolization of the feeding artery using gelatin sponge. Drug eluting beads (DEB) were introduced in clinical practice in the 2000s and have since been used as an alternative to c-TACE with better outcomes, especially in larger tumors.

Certified randomness using a trapped-ion quantum processor.

Although quantum computers can perform a wide range of practically important tasks beyond the abilities of classical computers, realizing this potential remains a challenge. An example is to use an untrusted remote device to generate random bits that can be certified to contain a certain amount of entropy. Certified randomness has many applications but is impossible to achieve solely by classical computation.

Long-term outcomes of biodegradable versus 2nd generation durable polymer drug-eluting stents in PCI: Protocol for a systematic review and meta-analysis.

Background: More than 3 million individuals globally experience STEMI each year, with percutaneous coronary intervention (PCI) as the preferred revascularization method. While second-generation Drug Eluting Stents (DES) reduce restenosis compared to bare-metal stents, complications such as neoatherosclerosis and stent thrombosis remain. Second-generation stents, including durable polymer (DP-DES) and biodegradable polymer (BP-DES), aim to improve outcomes, though guidelines do not specify a preference.

Bridging gaps in global surgery: Insights from an international hybrid conference.

This study explores the motivations for attendance, methods of conference promotion, and key considerations in implementing a hybrid conference for global surgery education among medical students and trainee doctors. The InciSion UK Global Surgery Conference 2023, held in London, provided a unique platform combining in-person and virtual participation. Pre- and post-conference surveys collected qualitative and quantitative data from 640 and 794 respondents, respectively.

Deciphering the Genetic Architecture of Parkinson's Disease in India.

The genomic landscape of the Indian population, particularly for age-related disorders like Parkinson's disease (PD) remains underrepresented in global research. Genetic variability in PD has been studied predominantly in European populations, offering limited insights into its role within the Indian population. To address this gap, we conducted the first pan-India genomic survey of PD involving 4,806 cases and 6,364 controls, complemented by a meta-analysis integrating summary statistics from a multi-ancestry PD meta-analysis (N=611,485).

Advances in Catalysts for Hydrogen Production: A Comprehensive Review of Materials and Mechanisms.

This review explores the recent advancements in catalyst technology for hydrogen production, emphasizing the role of catalysts in efficient and sustainable hydrogen generation. This involves a comprehensive analysis of various catalyst materials, including noble metals, transition metals, carbon-based nanomaterials, and metal-organic frameworks, along with their mechanisms and performance outcomes. Major findings reveal that while noble metal catalysts, such as platinum and iridium, exhibit exceptional activity, their high cost and scarcity necessitate the exploration of alternative materials.

Hospital-Based Surveillance of Respiratory Viruses Among Children Under Five Years of Age with ARI and SARI in Eastern UP, India.

Acute respiratory infections (ARIs) are a leading cause of death in children under five globally. The seasonal trends and profiles of respiratory viruses vary by region and season. Due to limited information and the population's vulnerability, we conducted the hospital-based surveillance of respiratory viruses in Eastern Uttar Pradesh.

Correlation between sarcopenia and hypertrophy of the future liver remnant in patients undergoing portal vein embolization before liver resection.

Objectives: To study the correlation between sarcopenia and hypertrophy of the future liver remnant (FLR) in patients undergoing portal vein embolization (PVE) before liver resection, and to assess the outcomes after resection.

Methods: This retrospective study examined patients underwent PVE from May 2012 to May 2023. Demographic, clinical, and laboratory features were documented and total liver volumes and FLR volumes were measured before and 2-4 weeks after PVE.