Hydrogel adhesives with a hydrodynamically induced liquid-solid transition for annular fissure sealing and inflammation modulation following microdiscectomy.

Background: Intervertebral disc (IVD) herniation is a major cause of low back pain and disability, with microdiscectomy being the standard surgical treatment. However, microdiscectomy fails to address annulus fibrosus (AF) defects, increasing the risk of recurrent herniation. Current therapeutic strategies for this condition remain limited in efficacy.

Exploring the structural links between peer support, psychological resilience, and exercise adherence in adolescents: a multigroup model across gender and educational stages.

Background: This study explored the associations among peer support, psychological resilience, and exercise adherence in adolescents, paying particular attention to different gender groups and educational stages. Psychological resilience was regarded as a potential explanatory mechanism in the relationship between peer support and exercise adherence.

Methods: A cross-sectional study with a mixed approach was conducted in Zhejiang Province, China (2023), involving a total of 2,137 adolescents (aged 10-18; 49.

Clinically Oriented Oral Environment-Triggered Underwater Adhesives for Root Caries Treatment through Dentinal Tubule Occlusion and Remineralization.

The application of silk fibroin (SF) hydrogels is often limited by their brittleness; on the other hand, increasing ductility can lead to insufficient strength of the hydrogel. These drawbacks make it difficult to apply to treat root surface caries, which are continuously exudated by crevicular fluid and have special locations and shapes. Herein, we design an underwater adhesive hydrogel with a fluid-solid spontaneous transition triggered by water for root caries treatment.

Hagfish-inspired hydrogel for root caries: A multifunctional approach including immediate protection, antimicrobial phototherapy, and remineralization.

Root caries is the main cause of oral pain and tooth loss in the elderly. Protecting root lesions from environmental disturbances, resisting pathogens, and facilitating remineralization over time are essential for addressing root caries, but are challenging due to the irregular root surface and the complex oral environment. Hagfish secretes slime when facing danger, which converts into gels upon contact with seawater, suffocating the predators.

Immunogenic and diagnostic potential of recombinant apical membrane antigen-1 from Plasmodium malariae.

The apical membrane antigen-1 (AMA-1) is a crucial target for malaria management and prevention strategies. While the immunogenicity of AMA-1 has been extensively studied for Plasmodium falciparum and Plasmodium vivax, there is a notable scarcity of information for Plasmodium malariae. In this study, recombinant PmAMA-1 was expressed in Escherichia coli, and its integrity was confirmed via western blotting and indirect immunofluorescence assays.

Exposure to cigarette taxes as a teenager and the persistence of smoking into adulthood.

Are teenage and adult smoking causally related? Recent anti-tobacco policy is predicated on the assumption that preventing teenagers from smoking will ensure that fewer adults smoke, but direct evidence in support of this assumption is scant. Using data from three nationally representative sources and instrumenting for teenage smoking with cigarette taxes experienced at ages 14-17, we document a strong positive relationship between teenage and adult smoking: deterring 10 teenagers from smoking through raising cigarette taxes roughly translates into 5 fewer adult smokers. We conclude that efforts to reduce teenage smoking can have long-lasting consequences on smoking participation and, presumably, health.

A preliminary composite of blood-based biomarkers to distinguish major depressive disorder and bipolar disorder in adolescents and adults.

Background: Since diagnosis of mood disorder heavily depends on signs and symptoms, emerging researches have been studying biomarkers with the attempt to improve diagnostic accuracy, but none of the findings have been broadly accepted. The purpose of the present study was to construct a preliminary diagnostic model to distinguish major depressive disorder (MDD) and bipolar disorder (BD) using potential commonly tested blood biomarkers.

Methods: Information of 721 inpatients with an ICD-10 diagnosis of MDD or BD were collected from the electronic medical record system.

Methodological comparison of bronchoalveolar lavage fluid-based detection of respiratory pathogens in diagnosis of bacterium/fungus-associated pneumonia in critically ill patients.

Background: Bacterium/fungus-associated pneumonia (BAP/FAP) is the prominent cause of high mortality and morbidity with important clinical impacts globally. Effective diagnostic methods and proper specimen types hopefully facilitate early diagnosis of pneumonia and prevent spread of drug-resistant bacteria/fungi among critically ill patients.

Methods: In the present study, 342 bronchoalveolar lavage fluid (BALF) samples were collected from critically ill patients with pulmonary infections between November 2020 and March 2021.

Precipitation extremes observed over and around the Taklimakan Desert, China.

The Taklimakan Desert (TD) is the largest desert in China located in the Tarim Basin (TB) in China's arid region. This study is a review of the change in precipitation and its extremes since 1961 and the high-impact extreme precipitation events in 2012-2021, particularly in 2021, with a focus on the TD along with the surrounding oases and mountainous regions.The TB has experienced significantly warmer and wetter trends since 1961, and extreme rainfall has increased significantly in the TD and its surrounding areas during the 2000s.

Heterogeneous CuO-Au nanocatalyst anchored on wood and its insight for synergistic photodegradation of organic pollutants.

In this study, a CuO-Au nanoparticles (NPs) heterojunction catalyst anchored on wood was developed by in situ reduction and hydrothermal treatment, and the properties of the catalyst were systematically characterized. The catalyst exhibited prominent photocatalysis of methyl orange (MO, 0.169 min), and tetracycline (TC, 0.

Comparative Analysis of Epidemiological and Clinical Characteristics Between Invasive Infection versus Colonization in Critically Ill Patients in a Tertiary Hospital in Anhui, China.

Objective: Invasive infections due to spp. have unique epidemiology, strain distribution, antimicrobial susceptibility, and clinical features. This study aimed to compare and evaluate these characteristic variables between invasive infection and colonization of critically ill patients in local China to potentially improve differential diagnosis and therapy.

The potential habitat of desert locusts is contracting: predictions under climate change scenarios.

Desert locusts are notorious for their widespread distribution and strong destructive power. Their influence extends from the vast arid and semiarid regions of western Africa to northwestern India. Large-scale locust outbreaks can have devastating consequences for food security, and their social impact may be long-lasting.

Applying Technology Acceptance Model in Online Entrepreneurship Education for New Entrepreneurs.

The present study aims to enrich the research on online entrepreneurship education, improve the level and ability of entrepreneurship services in China, and improve the overall success rate of entrepreneurship. Based on the technology acceptance model (TAM) proposed by researcher Davis, the study explores the application of TAM in online entrepreneurship education for new entrepreneurs. First, new entrepreneurs who are users of the online entrepreneurship education platform are selected as research objects, and then the influence of the four factors are studied, including perceived ease of use, perceived usefulness, classroom self-efficacy, and perceived external control.

Facile Fabrication of Three-Dimensional Fusiform-Like α-FeO for Enhanced Photocatalytic Performance.

α-FeO fusiform nanorods were prepared by a simple hydrothermal method employing the mixture of FeCl·6HO and urea as raw materials. The samples were examined by X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy and UV-vis diffuse reflectance spectra (UV-DRS). Its visible-light photocatalytic performances were evaluated by photocatalytic decolorization methylene blue (MB) in visible light irradiation.