Publications by authors named "Mostafa Abdelrahman"

Indigenous bacteria are very potent and useful in remediating hazardous pollutants specific to particular geographical locations. This work aimed to isolate two potent acid red dye decolorizing bacterial strains, namely Bacillus sp. strain UoMP1 and Citrobacter sp.

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Background: Different crops may recruit specific rhizosphere microbiomes that support their survival under unfavorable conditions, including hot semi-arid climates. However, the processes driving microbiome assembly within different crops and their adaptation to such extreme environmental conditions remain poorly understood. This study investigates whether upland cotton (Gossypium hirsutum), sorghum (Sorghum bicolor), and soybean (Glycine max) recruit distinct or overlapping rhizospheric bacterial communities under hot semi-arid conditions in Lubbock, Texas, United States, with a focus on their potential role in enhancing crop resilience.

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Drought stress significantly impairs growth and microbial interactions in sorghum. This study explores the transcriptional and microbial shifts in sorghum under drought, revealing key adaptations to water deficit. LC-MS (liquid chromatography-mass spectrometry) analyses revealed that drought stress induced abscisic acid while significantly reducing jasmonic acid levels in sorghum roots, likely due to resource conservation strategies during drought.

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A 35-year-old male, previously healthy, presented with epigastric and right hypochondrial pain, as well as a change in urine color. The diagnosis of a hepatic hydatid cyst with complications was confirmed based on clinical findings, ultrasound, and serology. The patient was treated with albendazole and underwent an ERCP (endoscopic retrograde cholangiopancreatography) for biliary involvement.

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Drought episodes, especially during the reproductive stages, have posed a significant threat to cotton production on a global scale. Finding an efficient solution that would bring immediate advantages to cotton producers has received unprecedented interest from the research community. Mineral supplements can play an important role in combating drought, while also improving fiber yield and cotton quality.

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The dark green coloration of bunching onion leaf blades is a key determinant of market value, nutritional quality, and visual appeal. This trait is regulated by a complex network of pigment interactions, which not only determine coloration but also serve as critical indicators of plant growth dynamics and stress responses. This study aimed to elucidate the mechanisms regulating the dark green trait and develop a predictive model for accurately assessing pigment composition.

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Introduction: Elevated atmospheric carbon dioxide [CO] increases peanut carbon assimilation and productivity. However, the molecular basis of such responses is not well understood. We tested the hypothesis that maintaining high photosynthesis under long-term elevated [CO] is associated with the shift in C metabolism gene expression regulation.

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The utilization of red and blue light-emitting diode (LED) lights for cultivating leafy vegetables in closed plant factories has increased in recent years. This study examined the growth and biosynthesis of functional compounds in twelve accessions, including cultivars and wild relatives, under the irradiation of fluorescent light and three different red-to-blue LED light combinations (red:blue = 1:1, 1:3, and 3:1). Results showed that, except for the three examined Japanese cultivars, the fresh weight of most spinach accessions increased when red light comprised 50-75% of the light's spectral composition.

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The bunching onion is an important leafy vegetable, prized for its distinctive flavor and color. It is consumed year-round in Japan, where a stable supply is essential. However, in recent years, the challenges posed by climate change and global warming have resulted in adverse effects on bunching onions, including stunted growth, discoloration, and the development of leaf tipburn, threatening both crop quality and yield.

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Background: In Ireland, radiographers typically work in the public or private sector. This study investigates the determinants influencing radiographers' employment choices between the public and private sectors, offering employers valuable insights into the key factors that shape these decisions.

Methods: An online questionnaire was distributed nationally via social media and email.

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Article Synopsis
  • - Cytokinin plays a crucial role in how plants, particularly Arabidopsis, adapt to arsenic (As(III)) stress by regulating root growth and cytokinin levels.
  • - The proteins ARR1 and ARR12 are identified as negative regulators in cytokinin signaling related to As(III) responses, affecting ion transport and nutrient usage in plants.
  • - Research shows that ARR1 and ARR12 enhance the expression of specific genes (NIP1;1 and NIP6;1) involved in arsenic uptake, which leads to increased arsenic accumulation under stress, offering insights for developing crops with reduced arsenic levels.
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The present study details the design, synthesis, and bio-evaluation of indoles as dual inhibitors of aromatase and inducible nitric oxide synthase (iNOS)with antiproliferative activity. The study evaluates the antiproliferative efficacy of against various cancer cell lines, highlighting hybrids and for their exceptional activity with GI values of 25 nM and 28 nM, respectively. The inhibitory effects of the most active hybrids , and , on both aromatase and iNOS were evaluated.

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Article Synopsis
  • COX-2-selective drugs were pulled from the market due to heart-related side effects, leading researchers to seek new COX-2 inhibitors that also protect cardiovascular health.
  • Newly created 15 diaryl-1,2,4-triazolo[3,4-]pyrimidine hybrids showed promising results as dual COX-2 and sEH inhibitors, with some compounds demonstrating greater potency and selectivity compared to celecoxib.
  • The most effective compounds also showed strong anti-inflammatory and analgesic properties while having a positive impact on heart health, and their molecular binding was analyzed to confirm their selectivity for COX-2.
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Isoprene, a volatile hydrocarbon, is typically emitted from the leaves of many plant species. Given its well-known function in plant growth and defense aboveground, we examined its effects on root physiology. We used isoprene-emitting (IE) lines and a non-emitting (NE) line of Arabidopsis and investigated their performance by analyzing root phenotype, hormone levels, transcriptome, and metabolite profiles under both normal and salt stress conditions.

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Article Synopsis
  • This review talks about how to use wild grasses to make modern bread wheat better for dealing with climate change and the need for more food.
  • It focuses on a special type of wheat called synthetic hexaploid wheat and mentions a specific wild grass called Aegilops tauschii that can help wheat become stronger against drought, heat, and salty conditions.
  • The review also highlights the scientific challenges faced when using wild grasses in wheat breeding and suggests using new technology to improve breeding methods for even better results.
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Climate change has resulted in an increased demand for Japanese bunching onions L., genomes FF) with drought resistance. A complete set of alien monosomic addition lines of with extra chromosomes from shallot ( L.

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To investigate the bioactivities of fresh garlic and its processed product, black garlic, we conducted comparative analyses of antioxidant, anti-inflammatory, innate immune activation, and anti-cancer activities in addition to the chemical composition (sugar, amino acid, and polyphenol contents) of these materials. Simultaneous assay using neutrophil-like cells showed that fresh garlic exhibited antioxidant and innate immunostimulatory activities, whereas black garlic displayed a potent anti-inflammatory effect. The antioxidant activity index was correlated with phenol and flavonoid contents, while the innate immunostimulatory activity was correlated with fructan content.

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Magnetic Resonance Imaging (MRI) is increasingly becoming a cornerstone in modern diagnostic healthcare, offering unparalleled capabilities in stroke, dementia, and cancer screening. Therefore, this study aims to map medical MRI literature affiliated with Arab countries, focusing on publication trends, top journals, author affiliations, study countries, and authors' collaboration, and keyword analysis. The scientific database used is the Scopus database.

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Nodule symbiosis is an energetic process that demands a tremendous carbon (C) cost, which massively increases in responses to environmental stresses. Notably, most common respiratory pathways (e.g.

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In the aftermaths of global warming, plants are more frequently exposed to the combination of heat stress and drought in natural conditions. Jasmonic acid (JA) has been known to modulate numerous plant adaptive responses to diverse environmental stresses. However, the function of JA in regulating plant responses to the combined effects of heat and drought remains underexplored.

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Rice () is a major crop and a main food for a major part of the global population. Rice species have derived from divergent agro-climatic regions, and thus, the local germplasm has a large genetic diversity. This study investigated the relationship between phenotypic and genetic variabilities of yield and yield-associated traits in Aus rice to identify short-duration, high-yielding genotypes.

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In recent times, the herbicide atrazine (ATZ) has been commonly used before and after the cultivation of crop plants to manage grassy weeds. Despite its effect, the toxic residues of ATZ affect soil fertility and crop yield. Hence, the current study is focused on providing insight into the degradation mechanism of the herbicide atrazine through bacterial chemotaxis involving intermediates responsive to degradation.

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A small set of indole-based derivatives, and -, was designed and synthesized. Compounds - demonstrated promising antiproliferative activity, with GI values ranging from 26 nM to 86 nM compared to erlotinib's 33 nM. The most potent antiproliferative derivatives-, , , , and -were tested for EGFR inhibitory activity.

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A new series of indole-2-carboxamides , and pyrido[3,4-b]indol-1-ones and have been developed as new antiproliferative agents that target both wild and mutant type EGFR. The antiproliferative effect of the new compounds was studied. , , , , , and have the highest antiproliferative activity with GI values ranging from 29 nM to 47 nM in comparison to the reference erlotinib (GI = 33 nM).

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A new series of 5-substituted-3-ethylindole-2-carboxamides 5a-k and 6a-c was designed and synthesised in an attempt to develop a dual targeted antiproliferative agent. Various spectroscopic methods of analysis were used to confirm the structures of the new compounds. The antiproliferative effect of compounds 5a-k and 6a-c against four cancer cell lines was investigated.

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