Long-term persistence of serum IgM antibodies against chikungunya virus in patients with chronic arthralgia.

Background: Anti-Chikungunya virus (CHIKV) IgM antibodies may persist for months after infection in some individuals, but the evidence is limited, and their exact duration remains unknown.

Objective: This study aimed to determine the duration for which anti-CHIKV IgM antibodies remain detectable following acute infection.

Methods: A commercial ELISA was used to assess the frequency of anti-CHIKV IgM antibody detection over time in 145 longitudinal serum samples obtained from 45 laboratory-confirmed chikungunya patients in Brazil (two to six samples per patient).

Impact of Antidepressants on Male Fertility and Seminal Parameters: A Systematic Review.

Depressive disorders affect a significant number of individuals worldwide, including men of reproductive age. The impact of antidepressant treatment on seminal and fertility parameters remains inconclusive, with limited clinical studies available on this topic. This systematic review aimed to compile the existing literature on the influence of various antidepressants on sperm and fertility-related parameters in men.

Chikungunya chronic arthralgia: impact on general and mental health and absenteeism from work.

Background: This study investigated the self-rated general health, mental health, and work absenteeism among patients with laboratory-confirmed chikungunya.

Methods: Telephone interviews were conducted with 63 patients ≥22 months after infection.

Results: Patients who reported (N=42) or did not report (N=21) chronic arthralgia, defined by duration ≥90 days, had different frequencies for low scores for general health (68.

Investigation of Delayed Transfusion Reactions in Sickle Cell Disease Patients Polytransfused in the Brazilian Amazon.

Background: Sickle cell disease (SCD) affects approximately 100,000 people in the United States and millions worldwide, with the highest prevalence of 70% of SCD being found in individuals of African ethnicity. Delayed hemolytic, alloimmunization, and anamnestic transfusion reactions in multiple transfusion patients need to be investigated and managed to avoid a worsening of the patient's clinical status.

Objective: This paper aims to investigate delayed transfusion reactions in SCD patients who were polytransfused in the Brazilian Amazon.

The Biological Role of Platelet Derivatives in Regenerative Aesthetics.

Bioproducts derived from platelets have been extensively used across various medical fields, with a recent notable surge in their application in dermatology and aesthetic procedures. These products, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), play crucial roles in inducing blood vessel proliferation through growth factors derived from peripheral blood. PRP and PRF, in particular, facilitate fibrin polymerization, creating a robust structure that serves as a reservoir for numerous growth factors.

A systematic study on the characteristics and applications of laccases produced by fungi: insights on their potential for biotechnologies.

Laccases are polyphenol oxidase enzymes and form the enzyme complex known for their role in wood decomposition and lignin degradation. The present study aimed to systematically review the state-of-the-art trends in scientific publications on laccase enzymes of the last 10 years. The main aspects checked included the laccase-producing fungal genera, the conditions of fungal growth and laccase production, the methods of immobilization, and potential applications of laccase.

Violence against women in the media during the Covid-19 pandemic.

Objective: To describe situations of violence against women in the Covid-19 pandemic reported in the media.

Method: Documentary, qualitative research, in a virtual environment, carried out with 39 reports published in the newspaper O Globo and the Universo On-line portal, between March 2020 and July 2021, in Salvador - BA. Data organization followed the steps of content analysis, with a discussion based on the scientific literature.

Balancing client preferences and population-level goals: a qualitative study of the ways in which public health providers and facility administrators interpret and incentivise quality of care in contraceptive counselling in Ethiopia, Mexico and India.

Recent work in family planning has shifted from an instrumentalist perspective on quality in contraceptive counselling, which views quality as a means to encourage contraceptive uptake, to privilege quality of care as a valued end in itself. In this context of shifting narratives about quality, it is important to understand how health systems and providers navigate potential conflicts between instrumentalist definitions of quality versus a person-centred definition that considers meeting clients' contraceptive needs and preferences as an important end goal in and of itself. However, we know little about how providers and other health system stakeholders interpret the concept of quality in counselling, and how their experiences with different quality monitoring systems influence their ability to provide person-centred care.

Water drinking during aerobic exercise improves the recovery of non-linear heart rate dynamics in coronary artery disease: crossover clinical trial.

Introduction: The post-exercise recovery is a period of vulnerability of the cardiovascular system in which autonomic nervous system plays a key role in cardiovascular deceleration. It is already known that individuals with coronary artery disease (CAD) are at greater risk due to delayed vagal reactivation in this period. Water ingestion has been studied as a strategy to improve autonomic recovery and mitigate the risks during recovery.

Trend in hospitalizations due to ambulatory care-sensitive conditions in the Federal District.

Objectives: to analyze the trend, according to sex, of Ambulatory Care-Sensitive Conditions in the Primary Health Care of the Federal District, from 2009 to 2019.

Methods: ecological trend study using ACSC hospitalization data available in the Hospitalization System of the Single Health System. The Prais-Winsten method was used to calculate the annual rate variation, expressed in percentages.

Influence of physical fitness of coronary disease patients on vagal reentry and heart rate recovery after exercise with and without fluid replacement.

Background: Fluid replacement during exercise has been studied as an important strategy to enhance recovery, however, studies are needed to investigate the effect of this strategy in different physical profiles. The aim of the study was to investigate the influence of physical fitness of coronary artery disease (CAD) patients on vagal reentry and heart rate recovery after exercise performed with and without fluid replacement.

Methods: Nonrandomized crossover clinical trial.

Analysis of Barriers to Public and Private Cardiac Rehabilitation Programs in Patients with Low and High Adherence.

Introduction: Participants in cardiac rehabilitation programs have low adherence to their sessions, which makes extremely important to recognize the barriers that cause non-adherence, identifying whether the type of service and level of adherence influence these barriers.

Methods: This is a cross-sectional observational study, in which 220 individuals (66.80±11.

The nurse's professional identity on the Primary Health Care users perception.

Objectives: to understanding the perception of Primary Health Care users about the professional identity of nurse.

Methods: this is an exploratory, descriptive, cross-sectional and quantitative study, using the STROBE instrument. The sample included 94 users grouped according to the Family Health Strategy coverage.

Millipore xMap® Luminex (HATMAG-68K): An Accurate and Cost-Effective Method for Evaluating Alzheimer's Biomarkers in Cerebrospinal Fluid.

Alzheimer's disease (AD) biomarkers are of great relevance in clinical research, especially after the AT(N) framework. They enable early diagnosis, disease staging and research with new promising drugs, monitoring therapeutic response. However, the high cost and low availability of the most well-known methods limits their use in low and medium-income countries.

+869 T > C (rs1800470) variant is independently associated with susceptibility, laboratory activity, and TGF-β1 in patients with systemic lupus erythematosus.

The aim of this study was to evaluate the association of the +869 T > C (rs1800470) and -509 C > T (rs1800469) variants, individually or in haplotypes structure, with susceptibility, autoantibodies, disease activity, and TGF-β1 plasma levels in patients with systemic lupus erythematosus (SLE). The study included 203 patients with SLE and 165 healthy controls. variants were determined by real-time polymerase chain reaction (qPCR).

Autonomic responses to facial expression tasks in children with autism spectrum disorders: Cross-section study.

Background: The autonomic nervous system has an influence on emotions and behavior modulation, however, the relationship between autonomic modulation impairment and the autism spectrum disorder (ASD) is yet to be fully described.

Aims: To evaluate the autonomic responses of children with and without ASD through the non-linear, and linear heart rate variability (HRV) measures, and assess the correlation between these responses, the severity and behavioral symptoms of autism.

Methods And Procedures: 27 children diagnosed with ASD (EG = experimental group) and 28 matching controls (CG = control group) were evaluated.

Vagal reactivation after a cardiac rehabilitation session associated with hydration in coronary artery disease patients: crossover clinical trial.

This study aimed to investigate the hydration influence on the autonomic responses of coronary artery disease subjects in the immediate recovery period after a cardiovascular rehabilitation session, in view of the risks of a delayed autonomic recovery for this population. 28 males with coronary artery disease were submitted to: (I) Maximum effort test; (II) Control protocol (CP), composed by initial rest, warm-up, exercise and passive recovery; (III) Hydration protocol (HP) similar to CP, but with rehydration during exercise. The recovery was evaluated through the heart rate (HR) variability, HR recovery and by the rate of perceived exertion and recovery.

Successful minimally invasive intervention in a primary central incisor after root fracture: A case report.

Root fractures vary in severity, extent, and location, according to the physical and mechanical aspects of the accident. Root fractures are rare in primary teeth and they affect dentin, cementum, periodontal ligament and the pulp. This paper reports a case of a two-and-a-half-year-old baby who had a root fracture of the upper right primary central incisor (tooth 51) as a consequence of trauma that was managed with minimally invasive intervention.

Older adults with epilepsy: memory complaints and objective neuropsychological performance.

Introduction: People with epilepsy frequently complain of poor memory.

Objective: To assess the occurrence of memory complaints in older adults with epilepsy (OAE) and whether it is associated with clinical variables, objective cognitive performance, and quality of life (QoL).

Methods: The Memory Complaint Questionnaire (MAC-Q) was related to objective cognitive performance, the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E), the Quality of Life in Epilepsy Inventory (QOLIE-31), and the clinical characteristics of 83 OAE.

Hydration Influence on the Autonomic Recovery of the Coronary Diseases Patient: Geometric Indices Analysis.

: To evaluate the recovery period of autonomic modulation, through geometric indices of heart rate variability (HRV), on coronary artery disease (CAD) patients submitted to a cardiovascular rehabilitation session (CR), associated with hydration. : Thirty male participants of a CR program, diagnosed with CAD were submitted to the control (CP) and hydration protocol (HP) characterized by a CR session. Only during HP were the participants given 8 equal portions of water.

Amlodipine Increases the Therapeutic Potential of Ravuconazole upon Trypanosoma cruzi Infection.

Mining existing agents that enhance the therapeutic potential of ergosterol biosynthesis inhibitors (EBI) is a promising approach to improve Chagas disease chemotherapy. In this study, we evaluated the effect of ravuconazole, an EBI, combined with amlodipine, a calcium channel blocker, upon experimental infection. assays confirmed the trypanocidal activity of both compounds in monotherapy and demonstrated an additive effect (sum of the fractional inhibitory concentration [ΣFIC] > 0.

How deadly sarcophagid fly larvae are for anurans? New interactions and review to Neotropical region.

Myiasis is defined as the infestation of living or necrotic tissues of vertebrates by dipteran larvae. In amphibians, it can be caused by fly larvae belonging to families Calliphoridae, Chloropidae, Muscidae, and Sarcophagidae. In this study, we report new records and infestation intensity of myiasis in anurans from two localities of the Atlantic Forest in southern Brazil, and also present a list with myiasis caused by flesh fly Sarcophagidae species in anurans of the Neotropical region.