Publications by authors named "Adriane S Paz"

Background: Anti-Chikungunya virus (CHIKV) IgM antibodies may persist for months after infection in some individuals, but the evidence is limited, and their exact duration remains unknown.

Objective: This study aimed to determine the duration for which anti-CHIKV IgM antibodies remain detectable following acute infection.

Methods: A commercial ELISA was used to assess the frequency of anti-CHIKV IgM antibody detection over time in 145 longitudinal serum samples obtained from 45 laboratory-confirmed chikungunya patients in Brazil (two to six samples per patient).

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Background: This study investigated the self-rated general health, mental health, and work absenteeism among patients with laboratory-confirmed chikungunya.

Methods: Telephone interviews were conducted with 63 patients ≥22 months after infection.

Results: Patients who reported (N=42) or did not report (N=21) chronic arthralgia, defined by duration ≥90 days, had different frequencies for low scores for general health (68.

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Background: Takayasu arteritis (TA) and tuberculosis (TB) share similar histopathological and immunological characteristics. Studies comparing patients with TA with or without active or latent TB infection (LTBI) have revealed some differences in clinical and angiographic profiles. Patient with TA and history of TB exhibited more constitutional symptoms and structural damage to the aorta.

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Article Synopsis
  • * A systematic analysis was conducted using the PubMed database, including 81 articles that featured 89 patients who developed vasculitis after being treated with various biological agents such as anti-TNF-a and others.
  • * The findings highlight that leukocytoclastic vasculitis (LCV) was the most common type observed, and while some patients switched medications, only a few experienced relapses, showing the complexity of managing autoimmune reactions to these therapies.
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Necrotizing sarcoid granulomatosis (NSG) is a rare and under-recognized cause of granulomatous disease, described as a variant of typical nodular sarcoidosis. It can be asymptomatic when the patient has a single pulmonary nodule or may be accompanied by cough, fever, and dyspnea, or even symptoms due to the involvement of other organs such as the eyes, liver, and central nervous system. The histopathological analysis is essential for the differential diagnosis of other infectious and non-infectious causes of granuloma and to determine the appropriate treatment.

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Introduction: We performed a systematic review of the literature to determine the value of bronchoalveolar lavage (BAL) in evaluating the pulmonary involvement of systemic sclerosis (SSc).

Methods: Articles published between 1980 and 2019 were retrieved from the databases: PubMed and Scielo. The search was restricted to clinical trials published in English, utilizing the keywords "scleroderma, systemic sclerosis, interstitial lung disease, and bronchoalveolar lavage".

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