Efficacy of pulsed radiofrequency stimulation in patients with chronic pain: a narrative review.

Objectives: The review aimed to evaluate the efficacy of pulsed radiofrequency (PRF) in treating chronic pain by analyzing recent literature.

Study Design: This is a narrative review of relevant articles on the effectiveness of PRF for chronic pain.

Methods: Search for papers published between November 2014 and November 2024 in the PubMed database that use PRF to treat chronic pain.

Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics.

Macrophages are heterogeneous immune cells with diverse subtypes and tissue-specific distributions, displaying dynamic polarization states that critically govern their immunomodulatory functions and responses to environmental cues. As key regulators of innate and adaptive immunity, they originate from either embryonic progenitors or bone marrow-derived monocytes and exhibit remarkable plasticity in response to microenvironmental cues. Tissue-resident macrophages (e.

Transcriptome reanalysis and gene expression of 13 detoxification genes for avermectin and pyridaben resistance in Panonychus citri.

Citrus red mites (P. citri) are key pests affecting citrus production worldwide due to pesticide resistance. The resistance mechanisms of ten pesticides are known, but a comprehensive study using transcriptome data is missing.

Downregulation of Egr-1 Expression Level via GluN2B Underlies the Antidepressant Effects of Ketamine in a Chronic Unpredictable Stress Animal Model of Depression.

Ketamine is a non-competitive antagonist of N-methyl-D-aspartate receptors (NMDARs). Growing evidence suggests that a single dose of ketamine produces a series of rapid and remarkable antidepressant properties. However, the mechanisms remain unclear.

Role of PAR2 in regulating oxaliplatin-induced neuropathic pain via TRPA1.

Oxaliplatin (OXL) is a third-generation chemotherapeutic agent commonly used to treat metastatic digestive tumors; however, one of the main limiting complications of OXL is neuropathic pain. In this study, the underlying mechanisms responsible for OXL evoked-neuropathic pain were examined. Using a rat model, the results demonstrated that intraperitoneal (i.