Dietary Improves Piglet Intestinal Health and Antioxidant Capacity via Regulating the Gut Microbiota.

Piglet diarrhea caused by weaning stress will increase the mortality rate and seriously affect swine industry production efficiency. Probiotic supplementation has been reported to effectively alleviate weaning diarrhea by inhibiting the colonization of pathogenic microorganisms; however, the underlying mechanisms remain unclear. In this study, we isolated a strain of and conducted a series of and experiments to explore its effects on weaned piglets.

Effects of Adding BCH0 to the Diet on Growth Performance, Tissue Structures, and Gut Microbiota in Broilers.

Studies demonstrated that () as a dietary additive enhanced broiler growth performance, yet its mechanisms of action modulation remained unclear. Therefore, this study investigated effects of dietary BCH0 (1 × 10 CFU/kg) on growth performance, intestinal morphology, gut microbiota, and ileal transcriptomics in Arbor Acres broilers using a completely randomized design. A total of 200 one-day-old broilers were allocated to control (Con, basal diet) and experimental (BCH0, basal diet + 1 × 10 CFU/kg BCH0) groups (10 replicates/group, 10 birds/replicate) over a 42-day trial.

Bacillus subtilis improves antioxidant capacity and optimizes inflammatory state in broilers.

Objective: Bacillus subtilis, a kind of probiotic with broad-spectrum antibacterial function, was commonly used in livestock and poultry production. Recent research suggested that Bacillus subtilis may have antioxidant properties and improve immune response. This study aimed to verify the probiotic function of Bacillus subtilis in the production of broiler chickens.

relieves weaning diarrhea improving gut microbiota and redox homeostasis using a piglet model.

Weaning stress commonly damages the intestinal barrier of mammals, resulting in gut microbiota dysbiosis, intestinal illness, and even severe diarrhea. Probiotics are used as a nutritional strategy to promote the health of humans and animals and the gut microbiota balance. Here was applied as a probiotic supplement to a weaned piglet model to investigate its impacts on growth performance, antioxidant capacity, inflammation response, and intestinal health.

improves intestinal barrier, antioxidant capacity and gut microbial composition in AA broiler.

can secret a variety of substances to improve human and animal gut health inhibiting the proliferation of pathogenic bacteria. In this study, a fast-growing and stress-resistant strain of () were isolated, which showed a strong antibacterial activity to K88, ATCC14028, and ATCC25923 . studies showed that can significantly improve the average daily gain (ADG) using an AA broiler model.

Gama-aminobutyric acid (GABA) alleviates hepatic inflammation via GABA receptors/TLR4/NF-κB pathways in growing-finishing pigs generated by super-multiparous sows.

The offspring of super-multiparous sows face problems such as decreased growth performance, poor meat quality and even diseases in animal husbandry. Gama-aminobutyric acid (GABA) has long been known to promote growth and suppress inflammation, but little is known about the mechanisms. A total of 72 growing-finishing pigs from the 8th generation were randomly allotted to 2 groups with 6 replicates per treatment to receive a corn-soybean basal diet or the basal diet supplemented 20 mg/kg GABA for 60 d.

Tibetan Pig-Derived Probiotic SLZX20-1 Improved Intestinal Function Producing Enzymes and Regulating Intestinal Microflora.

The interaction between exogenous microorganisms and the host has received great attention, and finding new probiotics is always the way to improve the health of humans and animals. () is a kind of that can efficiently utilize starch, as a food and feed additive, it has been widely used for mildew prevention and antibacterial, bacteriostasis, and enzyme production. Herein, a strain of was isolated from the feces of Tibetan weaned piglets, named SLZX20-1.

Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.

Functional amino acids provide great potential for treating autophagy-related diseases by regulating autophagy. The purpose of the autophagy process is to remove unwanted cellular contents and to recycle nutrients, which is controlled by many factors. Disordered autophagy has been reported to be associated with various diseases, such as cancer, neurodegeneration, aging, and obesity.

Impacts of Fructose on Intestinal Barrier Function, Inflammation and Microbiota in a Piglet Model.

The metabolic disorder caused by excessive fructose intake was reported extensively and often accompanied by intestinal barrier dysfunction. And the rising dietary fructose was consumed at an early age of human. However, related researches were almost conducted in rodent models, while in the anatomy and physiology of gastrointestinal tract, pig is more similar to human beings than rodents.

Moderate Dietary Protein Restriction Optimized Gut Microbiota and Mucosal Barrier in Growing Pig Model.

Appropriate protein concentration is essential for animal at certain stage. This study evaluated the effects of different percentages of dietary protein restriction on intestinal health of growing pigs. Eighteen barrows were randomly assigned to a normal (18%), low (15%), and extremely low (12%) dietary protein concentration group for 30 days.

Antioxidants Maintain Cellular Redox Homeostasis by Elimination of Reactive Oxygen Species.

Reactive oxygen species (ROS) are produced by living cells as normal cellular metabolic byproduct. Under excessive stress conditions, cells will produce numerous ROS, and the living organisms eventually evolve series of response mechanisms to adapt to the ROS exposure as well as utilize it as the signaling molecules. ROS molecules would trigger oxidative stress in a feedback mechanism involving many biological processes, such as apoptosis, necrosis and autophagy.

Dimethyl fumarate reduces the risk of mycotoxins via improving intestinal barrier and microbiota.

The effects of dimethyl fumarate (DMF) on mycotoxins and animal growth performance are well documented. However, its mechanism of anti-mildew effects is still unknown. The current study investigated how DMF detoxified the mycotoxin and improved the growth performance using BALB/c mice model, especially its effects on intestinal barrier function and gut micro-ecology.

Effects of replacing Leymus chinensis with whole-crop wheat hay on Holstein bull apparent digestibility, plasma parameters, rumen fermentation, and microbiota.

Twelve Holstein bulls were used in a 4 × 4 Latin square design to investigate the effects of using whole-crop wheat hay (WCWH) as a substitute for Leymus chinensis (LC) on apparent digestibility, plasma parameters, ruminal fermentation, and microbial communities. Experimental treatments were four proportions of WCWH, 0, 33, 67, and 100%, as a substitute for LC (WCWH0, WCWH33, WCWH67, and WCWH100, respectively). The WCWH100 group showed a higher nutritional intake of crude protein (CP) and higher apparent digestibility of organic matter (OM), CP, and ether extract (EE) than the WCWH0 group (P < 0.