Healthcare-seeking pathway and delay analysis of rifampicin-resistant tuberculosis patient in Southwestern China.

Objectives: Rifampicin-resistant tuberculosis (RR-TB) remains a critical health challenge in southwest China. This study investigates healthcare-seeking delays and patient pathways among RR-TB patients in Yunnan province, employing diagram visualization. Aim to explore the accessibility and challenges of medical services for RR-TB.

Outbreak of Beijing Strain in a High School in Yunnan, China.

In this study, we report an investigation of a tuberculosis (TB) outbreak in a high school in China. Eleven students with active TB were identified. A culture-negative 17-year-old girl was considered as index case affected by pulmonary and meningeal TB.

First Insight into the Molecular Epidemiology of Isolates from the Minority Enclaves of Southwestern China.

Yunnan is a province located in southwestern China. The aim of this study was to investigate the genetic diversity of (MTB) strains circulating in Yunnan Province. We used spoligotyping and a 12-locus high-resolution VNTR set to identify a total of 271 MTB isolates collected from six prefectures' Yunnan.

[Anti-fecundity effect of soluble immature egg antigen of Schistosoma japonicum in mice].

Objective: To study anti-female fecundity effect in mice immunized with soluble immature egg antigen (SIEA) of Schistosoma japonicum, and observe possible mechanism.

Methods: Immature eggs were collected from the liver of a rabbit 34 days after being infected with 3000 cercariae of S. japonicum, and soluble antigen was prepared routinely.

Effects of frozen storage on the structure of sarcocysts in pig muscle and implications in taxonomic studies.

Unlabelled: The morphology of the cyst wall of Sarcocystis has unique characteristics that can be used in species identification. To find a suitable way to preserve Sarcocystis cyst samples for species identification, by light microscopy and electron microscopy, we recorded the morphological changes in the cysts of Sarcocystis suihominis and Sarcocystis miescheriana from pig muscle, induced by storage at -20 degrees C. Comparisons were made between fresh cysts and those subjected to frozen storage for periods of 3 days, 20 days and 30 days.

Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity.

Anthranilamide analogues such as 23 are potent and highly selective muscarinic M2 antagonists that also show good oral bioavailability and in vivo activity.