Advancements in SELEX Technology for Aptamers and Emerging Applications in Therapeutics and Drug Delivery.

Nucleic acid aptamers, selected through the Systematic Evolution of Ligands by Exponential Enrichment (SELEX), are short nucleic acid sequences that exhibit high affinity and specificity towards diverse targets. Over the past three decades, substantial advancements have been made in both the technology and applications of nucleic acid aptamers. This review provides an in-depth analysis of the historical development and defining characteristics of aptamers, highlighting recent technological innovations in SELEX, including Capillary Electrophoresis SELEX, Microfluidic SELEX, Cell-SELEX, and others.

Optical design of an integrated imaging system of optical camera and synthetic aperture radar.

This paper presents an integrated imaging system of optical camera and synthetic aperture radar (SAR). The system can realize 400 nm-900 nm visible and near infrared band and 35 GHz microwave Ka band dual-band imaging. Compared with the single band imaging system, the observation ability and environmental adaptability of the integrated imaging system have been significantly improved.

Evaluation of two methods to minimize the anticlastic curvature of cylindrical bent crystals.

A scanning dynamically focusing sagittal X-ray monochromator accepting 3 mrad x 0.1 mrad from a 6 T wiggler has been designed for XAFS measurements. In the energy range 4.