Publications by authors named "Li-Fu Cheng"

Groundwater is one of the major water sources for production, living, and agricultural irrigation in the Yinchuan Plain. Owing to the influence of the regional environmental background and long-term effects of human activities, groundwater quality is generally inferior. To deeply analyze the formation mechanism and source of hydrochemical components in groundwater in the Yinchuan Plain, the traditional hydrochemical graphic method and mathematical statistics and principal component analysis-multivariate linear statistical model were used.

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Introduction: Free flap transfer for head and neck defects has gained worldwide acceptance. Because flap failure is a devastating outcome, studies have attempted to identify risk factors-including renal failure. We sought to determine whether end-stage renal disease (ESRD) patients undergoing dialysis are at increased risk of flap failure following microsurgical head and neck reconstruction.

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The sediment and soil in the Juma River channel pose a risk of pollution to the downstream ecological environment of Beijing and Xiong'an New Area. To address this issue, sediments and soil samples were collected along the river from the source to the Zhangfang outlet. The samples were further divided into three types:main stream sediment (29 samples), riverbank soil (27 samples), and farmland soil (26 samples).

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Reconstruction of the plantar forefoot area is challenging because it performs important functions, including carrying the body weight and balancing the ambulation gait, and lacks similar skin and soft tissues to manage the adjacent region. Herein, we shared our experience of using a lateral toe pulp flap and reviewed the relevant literature on this topic. A 33-year-old man presented with a large granuloma in the left plantar forefoot area after undergoing multiple operations owing to the diagnosis of callus.

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Article Synopsis
  • - Caspases, particularly caspase-3, are key proteases that play crucial roles in cell processes like differentiation, apoptosis (programmed cell death), and inflammation, and are linked to the effectiveness of cancer treatments.
  • - Breast cancer is the most prevalent cancer among women, making it a critical area for new treatment developments, with studies highlighting caspase-3's significant role in its progression and metastatic behavior.
  • - The review discusses how traditional Chinese medicine may influence caspase-3 expression, suggesting potential new therapeutic strategies for treating breast cancer by regulating cell death mechanisms.
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The Dandy-Walker malformation (DWM) is characterized by neuron dysregulation in embryonic development; however, the regulatory mechanisms associated with it are unclear. This study aimed to investigate the role of NADH dehydrogenase 1 alpha subcomplex 4 (NDUFA4) in regulating downstream signaling cascades and neuronal proliferation and apoptosis. Ndufa4 overexpression promoted the proliferation of neurons and inhibited their apoptosis in vitro, which underwent reverse regulation by the Ndufa4 short hairpin RNAs.

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All-inorganic halide perovskite nanocrystals (PNCs) have received increasing attention due to their excellent optical properties. However, the inherent instability and the large amount of volatile organic compounds during the production process have severely limited their applications. In this research, we employed the microfluidic electrostatic spinning method to synthesize polyvinylpyrrolidone (PVP)-based PNC (CsPbBr/PVP) powders directly by spinning chemistry, where the fibers serve as reactors.

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Purpose: The magnitude of muscle damage induced by maximal eccentric exercise is attenuated when the same exercise is repeated by homologous muscle of the ipsilateral or contralateral limb. It is not known if the muscle damage-protective effect is also transferred to nonhomologous muscles. The present study investigated the effects of unilateral knee extensor (KE) or flexor (KF) eccentric exercise on muscle damage induced by elbow flexor (EF) eccentric exercise of the ipsilateral or contralateral side.

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Background: In patients with diabetic foot ulcers requiring flap reconstruction, the choice of local flaps is limited by the lack of adequate tissue available. Free flaps are often bulky, presenting footwear difficulty due to poor contouring. Here, we present our experience of using the proximal lateral leg perforator flap in the reconstruction of thin diabetic foot ulcers.

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Background: When the distal dorsal part of the great toe is injured, especially with exposure of a tendon, bone, or joint, applying a free or local flap is difficult because of the lack of locally available tissue for reconstruction. Management of the distal dorsal part of a great toe soft tissue defect can be challenging for plastic surgeons.

Patient And Method: An 18-year-old woman presented with an injury to the dorsal aspect of her right great toe caused by a cobra bite.

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Background: Numerous conventional wound reconstruction methods, such as wound undermining with direct suture, skin graft, and flap surgery, can be used to treat large wounds. The adequate undermining of the skin flaps of a wound is a commonly used technique for achieving the closure of large tension wounds; however, the use of tension to approximate and suture the skin flaps can cause ischemic marginal necrosis. The purpose of this study is to use elastic rubber bands to relieve the tension of direct wound closure for simultaneously minimizing the risks of wound dehiscence and wound edge ischemia that lead to necrosis.

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Article Synopsis
  • The proximal lateral lower leg flap is ideal for reconstructing small, thin defects, and this study aimed to detail the perforator vessels in this area and assess their clinical reliability.
  • Dissections of 20 cadaver legs revealed 1-2 perforators per limb, predominantly septocutaneous, with a high survival rate of 95% observed in 22 clinical cases, despite one flap failure due to arterial thrombosis.
  • This flap is advantageous due to its thin, pliable nature, ease of harvesting, minimal complications at the donor site, and most cases allowing for primary closure.
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Free flaps have become a popular option for the reconstruction of intraoral defects. The radial forearm flap used to be the workhorse flap for small and thin defects, but was associated with numerous donor-site morbidities. The proximal lateral leg flap can provide a thin and pliable tissue similar to the radial forearm flap but without the related donor-site morbidities.

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We describe our experience in expanding the use of pedicled anterolateral thigh and vastus lateralis myocutaneous flaps. A total of 33 patients underwent 34 flaps between March 2003 and January 2012. The defects included 18 ischial, 3 trochanteric, 5 lower abdomen, 2 perineogenital, 1 groin, and 5 knee defects.

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Aim: To evaluate the feasibility, efficacy and safety of intraoperative radiofrequency ablation (RFA) combined with (125)iodine seed implantation for unresectable pancreatic cancer.

Methods: Thirty-two patients (21 males and 11 females) at the age of 68 years (range 48-90 years) with unresectable locally advanced pancreatic cancer admitted to our hospital from January 2006 to May 2008 were enrolled in this study. The tumor, 4-12 cm in diameter, located in pancreatic head of 23 patients and in pancreatic body and tail of 9 patients, was found to be unresectable during operation.

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Massive composite defects of the face are difficult to reconstruct. Such defects are usually created after ablation of advanced cancers of the head and neck region. The use of a free fibular osteocutaneous flap for the bone and mucosal lining of the oral cavity and anterolateral thigh flap for the outer cutaneous lining are well established.

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Objective: To discuss the relations of dental fluorosis and the social economic status in fluorosis-stricken villages where drying the corn by burning coal was prevail.

Methods: A total of 6 fluorosis-endemic villages and one non-endemic village were involved in the study. The general fluorine intake and the concentrations of fluorine in corn, in the pupils' were tested.

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Background: Extensive defects of the perineal area, with exposure of the testes, are difficult to reconstruct. Numerous reconstruction methods are available, but few provide us with an aesthetically acceptable, thin and pliable cover. The gracilis myocutaneous flap had the disadvantage of an unreliable skin paddle since McCraw's original description.

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We describe island pedicled anterolateral thigh and vastus lateralis myocutaneous flaps for reconstruction of the difficult, recurrent ischial pressure sore. Rather than transfer through a subcutaneous tunnel, the flap is transferred directly through the upper thigh to the ischial defect. A total of 15 patients with 16 recurrent ischial pressure sores were treated between May 2003 and April 2005.

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Background: Many Asian women are bothered by plump calves, which they consider to be unsightly. In the past, liposuction was frequently performed to treat oversized legs, but little effect could be obtained if the condition was caused by hypertrophy of calf muscles.

Methods: Gastrocnemius muscle resection for hypertrophic muscular calves was performed in 20 patients at Buddhist Tzu Chi General Hospital from May of 2001 through September of 2004.

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We derived a dressing using elastic rubber bands to tie over the skin graft. This is a simple, easy to perform, timesaving, inexpensive and reliable method for applying pressure over the skin graft compared with traditional methods. Between September 2002 and August 2004, we have used the present dressing technique in 35 patients with 36 grafts in various parts of the body.

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This study describes the use of the bilobed myocutaneous (MC) flap for reconstruction of trunk defect. The authors employ this flap because it offers a greater flexibility in the use of available tissue than many other local conventional flaps, is easy to design, safe to elevate, and causes minimal donor-site morbidity. The bilobed MC flaps are based on their main muscular pedicle.

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Patent microvascular anastomoses are mandatory for a successful free tissue transfer. Dextran 40 is widely used by reconstructive microsurgeons in conjunction with free tissue transfer, to prevent flap loss. Unfortunately, dextran-induced adverse reactions, such as anaphylactoid reactions, adult respiratory distress syndrome, cardiac overload, hemorrhage, and renal damage, remain the major risks in routine use of dextran 40.

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