Analysis of explanted Essure® devices.

Objective: The objective of this study was to understand the behavior of explanted Essure® devices in humans, focusing on the atomic composition of the device in different areas.

Methods: We collected 50 explanted Essure® devices (Bayer, Switzerland), in 29 patients. The following systematic investigations were performed on each devices: eye-nacked and optical microscopy, X-ray Faxitron, spectral analysis, elemental analysis of the metallic structure to accurately define the metallic composition of the spire and correlate these findings with macroscopic and microscopic observations.

A Distinct miRNA Profile in Intimal Hyperplasia of Failed Arteriovenous Fistulas Reveals Key Pathogenic Pathways.

Intimal hyperplasia (IH) compromises the patency of arteriovenous fistula (AVF) vascular access in patients with end-stage kidney disease. Uncontrolled cell proliferation and migration, driven by inflammation, shear stress and surgery, are well-known triggers in IH. Recently, microRNAs (miRNAs) have emerged as regulators of core mechanisms in cardiovascular diseases and as potential markers of IH.

Nellix Device Failure Mechanisms Analysis on Explanted Grafts.

Objective: To understand possible reasons for poor durability of the Nellix (Endologix Inc., Irvine, USA) endovascular aneurysm sealing (EVAS) device.

Materials And Methods: 21 Nellix endoprostheses explanted for endoleaks and migration underwent visual examinations of stent structures and instrumental examinations of the polymer endobags on 4 devices.

Editor's Choice -- Type IIIb Endoleaks: Fabric Perforations of Explanted New Generation Endoprostheses.

Objective: To analyse explanted endografts (EGs) and describe fabric degradation responsible for type IIIb endoleaks.

Methods: As part of the European collaborative retrieval programme, 32 EGs with fabric defects on macroscopic evaluation were selected. The explanted EGs were processed and studied based on the ISO 9001 certified standard protocol.