COSINE-100 full dataset challenges the annual modulation signal of DAMA/LIBRA.

For over 25 years, the DAMA/LIBRA collaboration has claimed to observe an annual modulation signal, suggesting the existence of dark matter interactions. However, no experiment using different target materials has observed a dark matter signal consistent with their result. To address this puzzle, the COSINE-100 collaboration conducted a model-independent test using sodium iodide crystal detectors, the same target material as DAMA/LIBRA.

Micro Orthogonal Fluxgate Sensor Fabricated with Amorphous CoZrNb Film.

We successfully fabricated micro orthogonal fluxgate sensors using amorphous CoZrNb films. The sensor, measuring 1.5 mm × 0.

Association Between Survival After Living Donor Liver Transplantation and Recipient Systemic Inflammation and Body Composition.

Preoperative sarcopenia in liver transplantation (LT) recipients is an important prognostic factor of LT outcomes. Systemic inflammatory status (SIS) has been proposed as a unifying mechanism for skeletal muscle loss; thus, considering SIS and sarcopenia together may enhance prognosis assessment in patients undergoing LT. Herein, we aimed to describe the relationship between the SIS and skeletal muscle index (SMI) with short-term and long-term mortality post-living donor LT (LDLT).

New Constraints on Axionlike Particles with the NEON Detector at a Nuclear Reactor.

We report new constraints on axionlike particles (ALPs) using data from the NEON experiment, which features 16.7 kg of NaI(Tl) target located 23.7 m from a 2.

Thigh muscle index as a valuable prognostic marker in middle-aged male patients undergoing liver transplantation.

In liver transplantation (LT), determining the optimal recipients is crucial, and the MELD score has been used for this purpose. However, the MELD score does not reflect functional status, leading to the evaluation of sarcopenia. While the L3 skeletal muscle index (SMI L3 ) is commonly used for assessment, the upper thigh skeletal muscle index (SMI UT ) may better represent functional capacity.

68Ga-DOTATOC PET/CT in the Localization of Pituitary Tumors in Cushing's Disease.

Backgruound: This study aimed to determine the value of 68Ga-DOTATOC positron emission tomography/computed tomography (PET/CT) in localizing adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas.

Methods: In this retrospective cohort study, we enrolled 30 patients with Cushing's disease and positive ACTH immunoreactivity. All patients underwent 68Ga-DOTATOC PET/CT and pituitary magnetic resonance imaging (MRI) before transsphenoidal adenomectomy.

Sex-specific effects of apolipoprotein E ε4 genotype on longitudinal hippocampal atrophy in amnestic mild cognitive impairment over a 2-year evaluation period.

Background: Hippocampal atrophy is implicated in the early onset of Alzheimer's disease (AD). It is closely associated with rapid cognitive decline and serves as a critical predictor for conversion from mild cognitive impairment (MCI) to AD. Consequently, with growing interest in utilizing hippocampal volume (HV) as an outcome measure in clinical trials, elucidating the neurobiological mechanisms underlying hippocampal atrophy is essential for early diagnosing AD and predicting its progression.

Efficacy of Virtual Reality Program for Mental Health Promotion in Pregnant Women.

Objective: Recently, various mental health promotion programs using virtual reality (VR) technology have been tried in the psychiatric field. Considering the importance of mental health in pregnant women, VR-assisted mental health promotion programs for pregnant women are needed to be developed. This study aimed to prospectively investigate the efficacy of a VR-assisted mental health promotion program for pregnant women.

First record of the family Calliopiidae (Crustacea, Malacostraca, Amphipoda) from Korean waters, with description of new species sp. nov.

A new species of the family Calliopiidae was collected from the East Sea of Korea. is similar to Bousfield & Hendrycks, 1997 in having numerous calceoli on the posteromedial margins of antennae and a weakly carinate body. However, the new species can be distinguished from by the shorter process on peduncular article 3 of antenna 1, subrectangular eyes, and fewer articles in the antenna flagellum.

Ultradian Rest-activity Rhythms Induced by Quinpirole in Mice Using Wavelet Analysis.

Objective: Ultradian rhythms are biological rhythms with periods of a few seconds to a few hours. Along with circadian rhythms, ultradian rhythms influence human physiology. However, such rhythms have not been studied as intensively as circadian rhythms.

A Bioinformatics Investigation of Hub Genes Involved in Treg Migration and Its Synergistic Effects, Using Immune Checkpoint Inhibitors for Immunotherapies.

This study aimed to identify hub genes involved in regulatory T cell (Treg) function and migration, offering insights into potential therapeutic targets for cancer immunotherapy. We performed a comprehensive bioinformatics analysis using three gene expression microarray datasets from the GEO database. Differentially expressed genes (DEGs) were identified to pathway enrichment analysis to explore their functional roles and potential pathways.

Solubility, complexation and thermodynamics of the Tc(IV)-isosaccharinic acid system: Trends in the M(IV) series.

Isosaccharinic acid (HISA, or ISA in its deprotonated form) is the main degradation product of cellulose under alkaline conditions. It can form strong complexes with radionuclides and other toxic metal ions, eventually enhancing their mobility in the context of nuclear waste repositories and other environmental systems. Tc is a redox-sensitive, long-lived fission product produced in high yield in nuclear reactors.

Differential gene expression and pathway analysis in growth hormone-secreting pituitary tumors according to granulation pattern.

This study investigated differential gene expression between granulation patterns in growth hormone (GH)-secreting pituitary tumors, aiming to elucidate novel transcriptomes that explain clinical variances in patients with acromegaly. Transcriptome analysis was conducted on 6 normal pituitary tissues and 15 GH-secreting pituitary tumors, including 9 densely granulated somatotroph tumors (DGSTs) and 6 sparsely granulated somatotroph tumors (SGSTs). We identified 3111 differentially expressed genes (DEGs) in tumors compared to normal pituitaries, with 1117 DEGs unique to a specific granulation within tumors.

Exploration of a Machine Learning Model Using Self-rating Questionnaires for Detecting Depression in Patients with Breast Cancer.

Objective: Given the long-term and severe distress experienced during breast cancer treatment, detecting depression among breast cancer patients is clinically crucial. This study aimed to explore a machine-learning model using self-report questionnaires to screen for depression in patients with breast cancer.

Methods: A total of 327 patients who visited the breast cancer clinic were included in this study.

Family-based genome-wide association analysis of novelty seeking in a Korean schizophrenic population: A pilot study.

Schizophrenia (SPR) is the most devastating mental illness that causes severe deterioration in social and occupational functioning, but, the etiology remains unknown. The objective of this study is to explore the genetic underpinnings of novelty seeking behavior in schizophrenic family within the Korean population. By conducting a family-based genome-wide association study, we aim to identify potential genetic markers and variations associated with novelty seeking traits in the context of SPR.

Subjective Experience on Virtual Reality-Assisted Mental Health Promotion Program.

Objective: Mental health promotion programs using virtual reality (VR) technology have been developed in various forms. This study aimed to investigate the subjective experience of a VR-assisted mental health promotion program for the community population, which was provided in the form of VR experience on a bus to increase accessibility.

Methods: Ninety-six people participated in this study.

Development of a Mature B Lymphocyte Probe through Gating-Oriented Live-Cell Distinction (GOLD) and Selective Imaging of Topical Spleen.

B lymphocytes play a pivotal role in the adaptive immune system by facilitating antibody production. Young B cell progenitors originate in the bone marrow and migrate to the spleen for antigen-dependent maturation, leading to the development of diverse B cell subtypes. Thus, tracking B cell trajectories through cell type distinction is essential for an appropriate checkpoint assessment.

The Dropout Rates and Associated Factors in Patients with Mood Disorders in Long-term Naturalistic Treatment.

Objective: Although maintenance treatment for mood disorders is important, the treatment discontinuation rate is reported to be high. This study aimed to investigate the dropout rates and associated factors in mood disorders.

Methods: The patients in a mood disorder clinic (n = 535) were examined.

Explainable prediction of problematic smartphone use among South Korea's children and adolescents using a Machine learning approach.

Background: Korea is known for its technological prowess, has the highest smartphone ownership rate in the world at 95%, and the smallest gap in smartphone ownership between generations. Since the onset of the COVID-19 pandemic, problematic smartphone use is becoming more prevalent among Korean children and adolescent owing to limited school attendance and outdoor activities, resulting in increased reliance on smartphones. 40.

A comparison of the perceived importance and performance of midwives' roles between midwives and nurses in Korea: a cross-sectional study.

Purpose: This study aimed to identify the perceptions, importance, and performance of midwives' roles among midwives and nurses in Korea.

Methods: A descriptive correlational design was employed. Data were collected from 164 nurses and 79 midwives from April 1 to June 25, 2021.