Prescription cost analysis and economic impact of drug treatment in patients with chronic illness, attending the medicine out-patient department in a tertiary care hospital at South Delhi.

Objectives: The prevalence of chronic diseases is rising globally along with the consumption of nutraceuticals. It is documented that 80% of the deaths due to chronic illnesses occur in low and middle-income countries, including India. In addition, chronic diseases not only affect the patients but also their family income.

New species and records of Sericinae from India and Nepal (Coleoptera: Scarabaeidae).

Here we describe six new sericine species (Coleoptera: Scarabaeidae: Sericinae) from India: Maladera champhaiensis Gupta, Bhunia, Ahrens & Chandra, sp. nov., Neoserica churachandpurensis Gupta, Bhunia, Ahrens & Chandra, sp.

A Catalogue of Indian Hydrophiloidea (Insecta: Coleoptera).

This catalogue lists 286 valid species included in 49 genera and six families of the superfamily Hydrophiloidea (Coleoptera), recorded from India. The family Helophoridae accommodates eight species (one genus), Epimetopidae five species (one genus), Georissidae seven species (one genus), Hydrochidae four species (one genus), Spercheidae two species (one genus), and Hydrophilidae 260 species (44 genera). Of these, 113 species are apparently endemic to India.

Triazole scaffold-based DPP-IV Inhibitors for the management of Type-II Diabetes Mellitus: Insight into Molecular Docking and SAR.

Diabetes mellitus, characterized as a chronic metabolic disorder or a polygenic syndrome; is increasing at a very fast pace among every group of the population worldwide. It arises due to the inability of the body to produce enough insulin (the hormone responsible for controlling blood sugar levels) or inability to utilize the insulin, leading to hyperglycaemic condition, which, if left uncontrolled gives rise to chronic microvascular and macrovascular complications like retinopathy, neuropathy, nephropathy, coronary artery disease, cognitive impairment, etc. Several therapeutic approaches are available for the treatment of diabetes; among which dipeptidyl peptidase (DPP-IV) inhibitors (gliptins) hold a significant place.

Efficacy of Standardized Yoga Asanas as Add-on Therapy in the Management of Hypothyroidism: A Randomized, Open-label, Controlled Clinical Study.

Background: Hypothyroidism is an endocrine disorder in which the thyroid gland does not produce an adequate amount of thyroid hormones. This study aimed to determine the efficacy of yoga asanas as an add-on therapy for the management of hypothyroidism.

Materials And Methods: For this interventional clinical study, a total of 450 study participants were screened for eligibility.

Unique among high passes: Insights into the genetic uniqueness among butterflies of Ladakh Trans-Himalaya through DNA barcoding.

Background: The butterfly assemblage of Ladakh Trans-Himalaya demands a thorough analysis of their population genetic structure owing to their typical biogeographic affinity and their adaptability to extreme cold-desert climates. No such effort has been taken till date, and in this backdrop, we created a COI barcode reference library of 60 specimens representing 23 species.

Methods And Results: Barcodes were generated from freshly collected leg samples using the Sanger sequencing method, followed by phylogenetic clade analyses and divergence calculation.

Unique among high passes: Phylogenetic inferences from DNA barcoding of the buttery fauna of Ladakh Trans-Himalaya, India.

The butterfly assemblage of Ladakh Trans-Himalaya demands a thorough analysis of their population genetic structure owing to their typical biogeographic affinity and their adaptability to extreme cold-desert climates. No such effort has been taken till date, and in this backdrop, we created a barcode reference library of 60 specimens representing 23 species. Barcodes were generated from freshly collected leg samples using the Sanger sequencing method, followed by phylogenetic clade analyses and divergence calculation.

Predicting the bioactive compounds of and elucidating its interaction with genes associated to obesity through network pharmacology and cell-based assay.

Mushrooms are traditionally used for various medicinal purposes in traditional oriental medicine. The Japanese and Chinese are familiar with the medicinal macro fungus ( mushroom). This study aims to evaluate the role of chemical compounds from using network pharmacology and studies for management of Obesity.

A new species of the genus Subniganda Kiriakoff, 1962 (Lepidoptera: Notodontidae) from India and Nepal.

The present paper describes a new species of Notodontidae Subniganda bambusoides Mazumder & Schintlmeister sp. nov. from the Himalayan and northeastern landscapes of India and Nepal.

Phenotyping of lymphocyte subsets, Th-1/Th-2 cytokines and other parameters in high-risk contacts of SARS-CoV-2.

Background: The information on the pathophysiology of infection in high-risk contacts of SARS-CoV-2 is limited.

Aims: The aim of the present study was to assess the various factors and their elucidation in the protection of SARS- CoV-2 infection in high-risk contacts.

Settings And Design: Cross-sectional descriptive clinical study.

Landscape genetics identified conservation priority areas for blue sheep (Pseudois nayaur) in the Indian Trans-Himalayan Region.

The trans-Himalayan region of India, although have xeric features, still supports a unique assemblage of biodiversity, including some of the charismatic and endemic species. In the present study, we studied blue sheep (Pseudois nayaur) across the distribution range in the Western trans Himalayas of India and found about 18,775 km area suitable for blue sheep. The explicit Bayesian based spatial and non-spatial population structure analysis assigned blue sheep into two genetic populations, i.

Mid-Pleistocene Transitions Forced Himalayan ibex to Evolve Independently after Split into an Allopatric Refugium.

Pleistocene glaciations had profound impact on the spatial distribution and genetic makeup of species in temperate ecosystems. While the glacial period trapped several species into glacial refugia and caused abrupt decline in large populations, the interglacial period facilitated population growth and range expansion leading to allopatric speciation. Here, we analyzed 40 genomes of four species of ibex and found that Himalayan ibex in the Pamir Mountains evolved independently after splitting from its main range about 0.

Visiting Ladakh Himalaya for a better knowledge of butterflies: new faunistic data with annotations (Lepidoptera, Papilionoidea).

The present study enumerates 65 species of Papilionoidea from the Ladakh Himalaya with the geographical locations and adult flight data. All the species are documented by museum vouchers. Most of the species recorded, have restricted distribution or they are endemic to the Pamir-NW Himalaya region.

Environmental predictors may change at fine scale habitat suitability modelling: implications for conservation of Kashmir musk deer in three protected areas of Uttarakhand, India.

The Kashmir musk deer (Moschus cupreus, hereafter KMD) is one of the top conservation priority species which is facing population decline due to poaching, habitat loss, and climate change. Therefore, the long-term survival and viability of KMD populations in their natural habitat require conservation and management of suitable habitats. Hence, the present study attempted to assess the suitable habitat of KMD in three protected areas (PAs) of the Western Himalayan region of Uttarakhand using the Maxent modelling algorithm.

Amemboa Esaki (Hemiptera: Gerromorpha: Gerridae) of India, with descriptions of two new species and establishment of species groups of world species.

Two new species of Gerridae, Amemboa latoae Jehamalar & Dash, new species and A. zetteli Jehamalar & Dash, new species, are described from India. Amemboa latoae is described from Meghalaya and can be recognised by the presence of the two setal tufts on the flexor region of the male fore femur and the slightly dilated midlateral region of the main part of the proctiger.

A catalogue of Indian Pyraloidea (Lepidoptera).

We catalogue 1,695 Indian Pyraloidea species in 509 genera. Of these, Pyralidae comprises 518 species in 182 genera, which represents 8.35% of the global Pyralidae diversity of 6,197 species.

New species and records of Sericini of India (Coleoptera: Scarabaeidae: Melolonthinae) III.

Here we describe two new species from India: Neoserica panchmariensis Bhunia, Gupta, Chandra & Ahrens, new species and N. debasriae Bhunia, Gupta, Chandra & Ahrens, new species. Moreover, Maladera pseudohongkongica Ahrens & Fabrizi, 2016 is recorded from Jharkhand state of India for the first time.

Review of Melolontha Fabricius, 1775 (Coleoptera: Scarabaeidae: Melolonthinae) from India with the description of two new species.

The genus Melolontha Fabricius, 1775 (Coleoptera: Scarabaeidae: Melolonthinae) from India is reviewed. Two new species, Melolontha arunachalensis Gupta, Keith, Bhunia, Das, Ghosh & Chandra, new species and Melolontha lachungensis Gupta, Keith, Bhunia, Das, Ghosh & Chandra, new species are described. Melolontha chinensis Guérin-Méneville, 1838 is reported for the first time from India.

A new distributional range of Abraxas antipusilla Inoue, 1995 (Lepidoptera: Geometridae) from Eastern Himalaya, India.

Based on Indian Himalayan expeditions, the species Abraxas antipusilla Inoue, 1995 is reported for the first time from Eastern Himalaya, India. After two decades, differential diagnoses of males and females are presented in comparison to Abraxas pusilla Butler, 1880. Redescriptions of male and female genitalia are given.

Lahaul-Zanskar-Sham Valley Corridor in Indian Trans Himalayan Region Facilitates Dispersal and Gene Flow in Himalayan Ibex.

Wildlife corridors that connect mosaic habitats in heterogeneous mountainous landscapes can be of high significance as they facilitate the genetic and demographic stability of free-ranging populations. Peripheral populations of widespread species are usually ignored in conservation planning. However, these populations retain locally common alleles and are genetic reservoir under the changing climatic conditions.

Long-term health consequences of COVID-19 in survivors hospitalised at a tertiary care hospital and their correlation with acute COVID-19 severity and associated risk factors.

Objectives: To determine post-COVID syndromes in the Indian population, correlating a wide spectrum of post-COVID manifestations with acute disease severity and associated risk factors.

Background: Post-COVID Syndrome (PCS) is defined as signs and symptoms that develop during or after acute COVID-19 infection.

Design Of Study: This is a prospective observational cohort with repetitive measurements.

Whether curse or blessing: A counterintuitive perspective on global pest thrips infestation under climatic change with implications to agricultural economics.

The improvement and application of pest models to predict yield losses is still a challenge for the scientific community. However, pest models were targeted chiefly towards scheduling scouting or pesticide applications to deal with pest infestation. Thysanoptera (thrips) significantly impact the productivity of many economically important crops worldwide.