Field-programmable robotic folding sheet.

Shape transformation by folding showcases intricate geometrical change over dimension, that has long provided the embodied intelligence of autonomous systems capable of adapting to challenging environments and displaying functional versatilities. Hinge-face material assembly interfaced by shape-morphing mechanisms produced the associated means. However, the fixed hinge structure limits the accessible modes of folding configurations despite the existing capability of rectification in plant.

Optimized bacterial delivery approaches for precision immunotherapy in breast cancer models.

Bacteria-mediated cancer therapy is an innovative approach that exploits the tumor-targeting ability of bacteria to deliver anti-cancer drugs directly to tumors. Cytolysin A (ClyA), a bacterial pore-forming toxin, has demonstrated therapeutic efficacy in colorectal cancer but has limited effectiveness in breast cancer. To address this limitation, we engineered an attenuated Salmonella strain to express Clostridium perfringens enterotoxin (CPE), which selectively targets CLDN-4, a tight junction protein overexpressed in breast cancer, thereby minimizing off-target effects.

SERS Sensor Integrated in Stretchable and Antimicrobial Wrapper for Food Quality Monitoring and Preservation.

In the wellness era, where food quality and safety are paramount, traditional food-monitoring methods, such as ribotyping and polymerase chain reaction, are often destructive and time-consuming, limiting their practicality for widespread application. Surface-enhanced Raman scattering (SERS) sensing is a promising alternative that offers real-time, nondestructive, and highly sensitive capabilities. This study proposes a nanostructured SERS sensor integrated into a stretchable and antimicrobial wrapper (NSSAW).

Thermoforming 2D films into 3D electronics for high-performance, customizable tactile sensing.

The demand for tactile sensors in robotics, virtual reality, and health care highlights the need for high performance and customizability. Despite advances in vision-based technologies, tactile sensing remains crucial for precise interaction and subtle pressure detection. In this work, we present a design and fabrication method of customizable tactile sensors based on thermoformed three-dimensional electronics.

Bioinspired interfacial engineering for highly stretchable electronics.

The seamless integration of rigid/flexible electronic components into stretchable substrates is imperative for the realization of reliable stretchable electronics. However, the transition from flexible-to-stretchable substrates presents inherent challenges in interfacial behavior, predominantly arising from disparities in elastic moduli, thereby rendering their integration arduous for practical deployment. Here, we introduce a bioinspired interface-engineered flexible island (BIEFI), which effectively facilitates the creation of highly stretchable electronics by optimizing the interface with flexible mechanical interlocking mechanisms, resilient to physical deformations.

Bioinspired Omnidirectional Interface Engineered Flexible Island for Highly Stretchable Electronics.

With the advancement of electronics, there is a growing need to effectively combine rigid, flexible, and stretchable materials to build hybrid electronics. However, the interfacial transition between rigid/flexible and stretchable substrates presents considerable challenges, mainly due to differences in elastic moduli, complicating their integration for practical usage. Here, bioinspired omnidirectional interfacial-engineered flexible islands (BOIEFI) are introduced for a robust transition from flexible to stretchable substrates.

Flexible All-Inorganic Thermoelectric Yarns.

Achieving both formability and functionality in thermoelectric materials remains a significant challenge due to their inherent brittleness. Previous approaches, such as polymer infiltration, often compromise thermoelectric efficiency, underscoring the need for flexible, all-inorganic alternatives. This study demonstrates that the extreme brittleness of thermoelectric bismuth telluride (BiTe) bulk compounds can be overcome by harnessing the nanoscale flexibility of BiTe nanoribbons and twisting them into a yarn structure.

Real-time detection of Tau-381 protein using liquid crystal-based sensors for Alzheimer's disease diagnosis.

Tau is a protein found in the central nervous system (CNS) and is involved in stabilizing microtubules in axons. Given the link between Tau levels in the body and Alzheimer's disease (AD), there is a demand for straightforward and precise strategies to detect Tau in body fluids. In this study, we report liquid crystal (LC)-based sensors for the real-time detection of Tau protein, a well-known AD biomarker.

Metasurface-Embedded Contact Lenses for Holographic Light Projection.

Contact lenses have been instrumental in vision correction and are expected to be utilized in augmented reality (AR) displays through the integration of electronic and optical components. In optics, metasurfaces, an array of sub-wavelength nanostructures, have offered optical multifunctionality in an ultra-compact form factor, facilitating integration into various imaging, and display systems. However, transferring metasurfaces onto contact lenses remains challenging due to the non-biocompatible materials of extant imprinting methods and the structural instability caused by the swelling and shrinking of the wetted surface.

Battery-Free, Wireless Multi-Modal Sensor, and Actuator Array System for Pressure Injury Prevention.

Simultaneous monitoring of critical parameters (e.g., pressure, shear, and temperature) at bony prominences is essential for the prevention of pressure injuries in a systematic manner.

Synthesis, Antiproliferative Activity and Molecular Docking Analysis of Both Enantiomerically Pure Decursin Derivatives as Anticancer Agents.

Using (S)-decursinol isolated from root of Angelica gigas Nakai (AGN), we semi-synthesized and evaluated a series of both enantiomerically pure decursin derivatives for their antiproliferative activities against A549 human lung cancer cells. All synthesized compounds showed a broad spectrum of inhibitory activities against the growth of A549 cells. Especially, compound (S)-2d with (E)-(furan-3-yl)acryloyl group showed the most potent activity (IC: 14.

Nanoribbon Yarn with Versatile Inorganic Materials.

Nanomaterial-based yarns have been actively developed owing to their advantageous features, namely, high surface-area-to-volume ratios, flexibility, and unusual material characteristics such as anisotropy in electrical/thermal conductivity. The superior properties of the nanomaterials can be directly imparted and scaled-up to macro-sized structures. However, most nanomaterial-based yarns have thus far, been fabricated with only organic materials such as polymers, graphene, and carbon nanotubes.

Deep learning-based automated detection of the dental crown finish line: An accuracy study.

Statement Of Problem: The marginal fit of dental prostheses is a clinically significant issue, and dental computer-aided design software programs use automated methods to expedite the extraction of finish lines. The accuracy of these automated methods should be evaluated.

Purpose: The purpose of this study was to compare the accuracy of a new hybrid method with existing software programs that extract finish lines using fully automated and semiautomated methods.

Illuminating Recent Progress in Nanotransfer Printing: Core Principles, Emerging Applications, and Future Perspectives.

As the demand for diverse nanostructures in physical/chemical devices continues to rise, the development of nanotransfer printing (nTP) technology is receiving significant attention due to its exceptional throughput and ease of use. Over the past decade, researchers have attempted to enhance the diversity of materials and substrates used in transfer processes as well as to improve the resolution, reliability, and scalability of nTP. Recent research on nTP has made continuous progress, particularly using the control of the interfacial adhesion force between the donor mold, target material, and receiver substrate, and numerous practical nTP methods with niche applications have been demonstrated.

Time efficiency, occlusal morphology, and internal fit of anatomic contour crowns designed by dental software powered by generative adversarial network: A comparative study.

Objectives: To evaluate the time efficiency, occlusal morphology, and internal fit of dental crowns designed using generative adversarial network (GAN)-based dental software compared to conventional dental software.

Methods: Thirty datasets of partial arch scans for prepared posterior teeth were analyzed. Each crown was designed on each abutment using GAN-based software (AI) and conventional dental software (non-AI).

Correction: A wearable colorimetric sweat pH sensor-based smart textile for health state diagnosis.

Correction for 'A wearable colorimetric sweat pH sensor-based smart textile for health state diagnosis' by Ji-Hwan Ha , , 2023, , 4163-4171, https://doi.org/10.1039/d3mh00340j.

Recent Advances in Sensor-Actuator Hybrid Soft Systems: Core Advantages, Intelligent Applications, and Future Perspectives.

The growing demand for soft intelligent systems, which have the potential to be used in a variety of fields such as wearable technology and human-robot interaction systems, has spurred the development of advanced soft transducers. Among soft systems, sensor-actuator hybrid systems are considered the most promising due to their effective and efficient performance, resulting from the synergistic and complementary interaction between their sensor and actuator components. Recent research on integrated sensor and actuator systems has resulted in a range of conceptual and practical soft systems.

Highly Sensitive Soft Pressure Sensors for Wearable Applications Based on Composite Films with Curved 3D Carbon Nanotube Structures.

Soft pressure sensors based on 3D microstructures exhibit high sensitivity in the low-pressure range, which is crucial for various wearable and soft touch applications. However, it is still a challenge to manufacture soft pressure sensors with sufficient sensitivity under small mechanical stimuli for wearable applications. This work presents a novel strategy for extremely sensitive pressure sensors based on the composite film with local changes in curved 3D carbon nanotube (CNT) structure via expandable microspheres.

Sensitive detection of 17β-estradiol at a picomolar level using an aptamer-assisted liquid crystal-based optical sensor.

A liquid crystal (LC)-based aptasensor was developed that can detect 17β-estradiol (E2) at the picomolar level. This aptasensor is based on competitive reactions of the aptamer that interacts with cetyl trimethyl ammonium bromide (CTAB) and E2 at the aqueous/LC interface. The long alkyl chain of CTAB anchored the 4-cyano-4'-pentylbiphenyl (5CB) to a homeotropic state and controls the local anchoring depending on the extent of electrostatic interaction with the aptamer.

A wearable colorimetric sweat pH sensor-based smart textile for health state diagnosis.

Sweat pH is an important indicator for diagnosing disease states, such as cystic fibrosis. However, conventional pH sensors are composed of large brittle mechanical parts and need additional instruments to read signals. These pH sensors have limitations for practical wearable applications.

Recent Advances in Triboelectric Nanogenerators: From Technological Progress to Commercial Applications.

Serious climate changes and energy-related environmental problems are currently critical issues in the world. In order to reduce carbon emissions and save our environment, renewable energy harvesting technologies will serve as a key solution in the near future. Among them, triboelectric nanogenerators (TENGs), which is one of the most promising mechanical energy harvesters by means of contact electrification phenomenon, are explosively developing due to abundant wasting mechanical energy sources and a number of superior advantages in a wide availability and selection of materials, relatively simple device configurations, and low-cost processing.

Micro-/Nanohierarchical Structures Physically Engineered on Surfaces: Analysis and Perspective.

The high demand for micro-/nanohierarchical structures as components of functional substrates, bioinspired devices, energy-related electronics, and chemical/physical transducers has inspired their in-depth studies and active development of the related fabrication techniques. In particular, significant progress has been achieved in hierarchical structures physically engineered on surfaces, which offer the advantages of wide-range material compatibility, design diversity, and mechanical stability, and numerous unique structures with important niche applications have been developed. This review categorizes the basic components of hierarchical structures physically engineered on surfaces according to function/shape and comprehensively summarizes the related advances, focusing on the fabrication strategies, ways of combining basic components, potential applications, and future research directions.

Piezo-Transmissive Structure Using a Multi-layered Heterogeneous Film for Optical Transmittance Modulation.

As the damage caused by the recent climate crisis increases, efforts are being made to develop low-power and high-efficiency technologies to reduce pollution for energy production worldwide. Among them, research on the mechano-responsive optical transmittance modulation technology is being actively conducted as it can be applied to various application fields for reducing energy consumption: low-power sensors and smart windows. The piezo-transmittance structure, which is one of the optical transmittance modulation structures, has fewer constraints on the installation environment; therefore, many applications have been proposed.

Nanotransfer-on-Things: From Rigid to Stretchable Nanophotonic Devices.

The growing demand for nanophotonic devices has driven the advancement of nanotransfer printing (nTP) technology. Currently, the scope of nTP is limited to certain materials and substrates owing to the temperature, pressure, and chemical bonding requirements. In this study, we developed a universal nTP technique utilizing covalent bonding-based adhesives to improve the adhesion between the target material and substrate.

Nanoscale three-dimensional fabrication based on mechanically guided assembly.

The growing demand for complex three-dimensional (3D) micro-/nanostructures has inspired the development of the corresponding manufacturing techniques. Among these techniques, 3D fabrication based on mechanically guided assembly offers the advantages of broad material compatibility, high designability, and structural reversibility under strain but is not applicable for nanoscale device printing because of the bottleneck at nanofabrication and design technique. Herein, a configuration-designable nanoscale 3D fabrication is suggested through a robust nanotransfer methodology and design of substrate's mechanical characteristics.