Physiological, Biochemical, and Molecular Mechanisms of Resistance of to .

The rust disease caused by seriously affects the growth of However, the defense mechanisms against rust infection remain unclear. This study explored the regulatory mechanisms of in response to rust disease through combined physiological, biochemical, and transcriptomic analyses. The results showed that with the increase in disease severity, the chlorophyll content of leaves decreased significantly, while the antioxidant and phenylalanine ammonia lyase activities progressively increased.

Suppressing sediment nutrient release via electrokinetic drainage of porewater: apparent paradox and underlying mechanisms.

Sediment nitrogen and phosphorus release drives internal eutrophication in many waterbodies, with nutrient-rich porewater serving as the key pathway for nutrient transfer to overlying water. In this study, electrokinetic geosynthetics (EKGs) were employed as electrodes to drain porewater and suppress sediment nutrient release. Five treatment groups with varying voltage gradients and power-on modes were tested.

Accuracy of Freestyle Libre continuous glucose monitoring system in critically ill patients after cardiac surgery.

Background: Hyperglycemia is an independent risk factor for perioperative complications and mortality after cardiac surgery. Freestyle Libre Continuous glucose monitor (CGM) is an interstitial glucose monitoring system, which has been proven to be stable and accurate in various disease.

Materials And Methods: 86 patients with hyperglycemia after cardiac surgery between October 2021 and October 2022 in the cardiovascular ICU, were enrolled in this study.

Histone-acetyl epigenome regulates TGF-β pathway-associated chemoresistance in colorectal cancer.

TGF-β signaling pathway has been demonstrated to be closely related to chemoresistance, which is the major cause of recurrence and poor outcome in colorectal cancer (CRC), however, the comprehensive epigenetic landscape that functionally implicates in the regulation of TGF-β pathway-associated chemoresistance has not yet well established in CRC. In our study, chromatin immunoprecipitation sequencing (ChIP-seq) and Western blot were employed to investigate epigenetic modifications for histones in response to TGF-β1 intervene. We found that the activation of the TGF-β pathway was characterized by genome-wide high levels of H3K9ac and H3K18ac.

La (NO) substantially fortified Glycyrrhiza uralensis's resilience against salt stress by interconnected pathways.

The taproot of Glycyrrhiza uralensis is globally appreciated for its medicinal and commercial value and is one of the most popular medicinal plants. With the decline of wild G. uralensis resources, cultivated G.

Lanthanum Significantly Contributes to the Growth of the Fine Roots' Morphology and Phosphorus Uptake Efficiency by Increasing the Yield and Quality of Taproots.

The occurrence of different degrees of phosphorus deficiency in the vast majority of cultivation regions worldwide is common. There is a pressing need within the cultivated industry to identify appropriate exogenous substances that can enhance the uptake of phosphorus and improve both the yield and quality of the taproots of . This study was conducted to investigate the fine root and taproot morphology, physiological characteristics, and secondary metabolite accumulation in response to the supply of varying concentrations of LaCl to , to determine the optimal concentration of LaCl that can effectively enhance the yield and quality of 's taproots, while also alleviating its reliance on soil phosphate fertilizer.

Maternal Effects of Habitats Induce Stronger Salt Tolerance in Early-Stage Offspring of from Salinized Habitats Compared with Those from Non-Salinized Habitats.

(1) Wild Fisch (licorice) seeds from different habitats are often mixed for cultivation. However, differences in the responses of seeds from different habitats to salt at the early-stage offspring stage are unclear. (2) Our objective was to evaluate the salt tolerance of germplasms by comparing differences in seed germination and seedling vigor in salinized (abandoned farmland and meadow) and non-salinized (corn farmland edge) soil habitats under different sodium chloride (NaCl) concentrations.

Leiomyosarcoma with osteoclast-like (LMS-OGC) giant cells the breast: A report of a rare case.

Leiomyosarcoma with osteoclast-like giant cells (LMS-OGC) has seldom been reported clinically. LMS-OGC of the breast is extremely rare according to the literature. Here, we report a case of LMS-OGC leiomyosarcoma with osteoclast-like giant cells of the breast.

Risk factors for postoperative delirium in patients after coronary artery bypass grafting: A prospective cohort study.

Purpose: This study was designed to identify the incidence and independent perioperative risk factors associated with postoperative delirium of patients who underwent coronary artery bypass grafting (CABG) in a large intensive care unit setting in China.

Methods: Delirium was diagnosed by the confusion assessment method for the intensive care unit (CAM-ICU). Baseline demographics, perioperative data, and postoperative outcomes of 249 consecutive patients who underwent CABG were recorded prospectively and analyzed via univariate analysis and multivariate logistic regression to determine the independent risk factors of postoperative delirium.

Differential signature of fecal microRNAs in patients with pancreatic cancer.

The potential value of microRNAs as new biomarkers for pancreatic cancer (PCa) screening was explored in this study. Fecal microRNAs from stool samples obtained from 29 PCa patients, 22 chronic pancreatitis (CP) patients and 13 normal individuals were extracted, and 7 microRNAs (miR-16, miR-21, miR-155, miR-181a, miR-181b, miR-196a and miR-210) were detected. miR-181b and miR-210 discriminated PCa from normal individuals with receiver operating characteristic (ROC) curves and area under curve (AUC-ROC) of 0.

Comparison of antioxidative and antifibrotic effects of α-tocopherol with those of tocotrienol-rich fraction in a rat model of chronic pancreatitis.

Objectives: The α-tocopherol and tocotrienol-rich fraction (TRF) are considered effective antioxidants. This study aimed to compare the antioxidative and antifibrotic effects of α-tocopherol and TFR in dibutylin dichloride (DBTC)-induced chronic pancreatitis (CP) rats.

Methods: Oral administration of α-tocopherol and TFR (both 800 mg/kg per day) started the next day after DBTC (8 mg/kg) infusion into the tail vein for 4 weeks.

Combination of plasma microRNAs with serum CA19-9 for early detection of pancreatic cancer.

This study was performed to identify plasma microRNAs (miRNAs) as diagnostic biomarkers for pancreatic cancer (PCa) and to assess their supplementary role with serum CA19-9 in early identification of tumors. Plasma RNAs were extracted from 140 PCa patients, 111 chronic pancreatitis (CP) patients and 68 normal controls, and the relative abundances of seven miRNAs (miR-16, 21, 155, 181a, 181b, 196a and 210) were measured using real-time PCR. Their diagnostic utility for PCa and correlation with clinical characteristics were analyzed.

Detection of KRAS gene mutations in endoscopic ultrasound-guided fine-needle aspiration biopsy for improving pancreatic cancer diagnosis.

Objectives: Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) is a useful tool in the diagnosis of pancreatic masses. Genetic analysis of these samples could increase the sensitivity and specificity of diagnosis. This study aimed to evaluate the usefulness of a novel method for the detection of mutations in the KRAS (Kirsten rat sarcoma-2 virus) gene for the diagnosis of pancreatic cancer.

Plasma miR-216a as a potential marker of pancreatic injury in a rat model of acute pancreatitis.

Aim: To study the potential value and specificity of plasma miR-216a as a marker for pancreatic injury.

Methods: Two rat models were applied in this article: L-arginine-induced acute pancreatitis was used as one model to explore the potential value of plasma miR-216a for detection of pancreatic injury; nonlethal sepsis induced in rats by single puncture cecal ligation and puncture (CLP) was used as the other model to evaluate the specificity of plasma miR-216a compared with two commonly used markers (amylase and lipase) for acute pancreatitis. Plasmas were sampled from rats at indicated time points and total RNA was isolated.