The impact of a varicella vaccine introduction on the incidence of herpes zoster in Korean children, an ecological study.

Objectives: SKYVaricella, a live attenuated varicella vaccine product, is known to increase the risk of herpes zoster (HZ) in vaccinated children. We investigated the impact of introducing the vaccine on HZ incidence in Korea since 2018.

Methods: This ecological study used medical records from the Health Insurance Review and Assessment Service in Korea.

Arrhythmic Risk and Clinical Features in Catecholaminergic Polymorphic Ventricular Tachycardia: Results From a Multicenter Study in Korea.

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but life-threatening inherited arrhythmia in children, often associated with sudden cardiac death (SCD). Risk stratification remains challenging. This study aimed to assess clinical characteristics, genetic profiles, and risk factors for adverse outcomes in Korean pediatric CPVT patients.

Gut Microbial Signatures in Long COVID: Potential Biomarkers and Therapeutic Targets.

Introduction: Following severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection, symptoms can persist for more than 12 weeks in over 10% of patients in a condition known as long coronavirus disease (COVID). Gut microbiota dysbiosis is correlated with long COVID, but the specific relationship between long COVID and the gut microbiome remains unclear. Here, we aimed to investigate connections between the gut microbiota and long COVID severity.

Growing vegetables in a warming world - a review of crop response to drought stress, and strategies to mitigate adverse effects in vegetable production.

Drought stress caused by climate change is increasingly affecting the productivity and quality of vegetable crops worldwide. This review comprehensively analyzes the physiological, biochemical, and molecular mechanisms that vegetable crops employ to cope with drought stress. In particular, it highlights the significance of key hormonal regulation pathways, such as abscisic acid (ABA), jasmonic acid (JA), and ethylene (ET), which play crucial roles in mediating stress responses.

Phase 2 Open-label, Single-arm, Multi-center Clinical Trial to Evaluate the Efficacy and Safety of Camostat Mesylate in Patients with Protein-losing Enteropathy After Fontan Operation.

Protein-losing enteropathy (PLE) is a serious complication after the Fontan operation with limited treatment options. This phase 2, multi-center, open-label trial evaluated the efficacy and safety of Camostat Mesylate (CM), a serine protease inhibitor, as adjunctive therapy for PLE. Nineteen patients aged 4 years and older with PLE after the Fontan operation were enrolled.

Assessing risk factors for foodborne illness in restaurants in Seoul.

Restaurants are the most common locations for foodborne infectious disease outbreaks in Korea, accounting for almost half of the annual outbreaks nationwide. Although significant efforts have been made to reduce the incidence of foodborne illnesses, factors contributing to these outbreaks have not been adequately elucidated. The purpose of this study was to assess the risk factors for foodborne illnesses in restaurants in Seoul using the recommendations of the U.

Erratum: Correction of Text in the Article "The Long-term Outcomes and Risk Factors of Complications After Fontan Surgery: From the Korean Fontan Registry (KFR)".

This corrects the article on p. 653 in vol. 54, PMID: 39175341.

Treatment Outcomes in Children With Catecholaminergic Polymorphic Ventricular Tachycardia: A Single Institutional Experience.

Background And Objectives: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a life-threatening inherited arrhythmogenic disorder. Recently, , the major CPVT-causative gene, was associated with neuropsychiatric manifestations. We aimed to analyze the clinical presentations, neuropsychiatric manifestations, and treatment outcomes of children with CPVT.

Long-term outcomes of extracardiac Gore-Tex conduits in Fontan patients.

Background: Extracardiac conduit Fontan procedure (ECFP) employing a Gore-Tex conduit has been widely used for patients with single ventricle physiology; however, the long-term status of the conduit is unknown. We investigated the changes in a Gore-Tex conduit after ECFP and the factors associated with its narrowing.

Methods: We conducted a retrospective analysis of 86 patients who underwent ECFP between January 1995 and December 2008 and had cardiac computed tomography (CT) during the follow-up period.

Pertussis epidemic in Korea and implications for epidemic control.

The pertussis epidemic in Korea is ongoing, with a record-high incidence rate. Although pertussis incidence is high worldwide in 2024, the scale of the increase observed in Korea is unprecedented and incomparable to that in other countries. The high proportion of cases among children aged 5 to 14 years is the distinctive characteristics of the 2024 pertussis epidemic in Korea.

Association between metabolically healthy obesity and carotid intima-media thickness in Korean adolescents with overweight and obesity.

Purpose: Data regarding the association between metabolically healthy obesity (MHO) and preclinical atherosclerosis in childhood are lacking. Carotid intima-media thickness (cIMT) is a noninvasive method used to assess cardiovascular risk. This study examined the relationships among cIMT, metabolic phenotypes, and cardiometabolic risk factors (CMRFs) in overweight and obese adolescents.

Correction to: A combined extract containing (SCE) reduced hepatic triglyceride accumulation in rats fed a high‑sucrose diet.

[This corrects the article DOI: 10.1007/s10068-023-01464-1.].

The Long-term Outcomes and Risk Factors of Complications After Fontan Surgery: From the Korean Fontan Registry (KFR).

Background And Objectives: This study aimed to analyze the outcomes of Fontan surgery in the Republic of Korea, as there were only a few studies from Asian countries.

Methods: The medical records of 1,732 patients who underwent Fontan surgery in 10 cardiac centers were reviewed.

Results: Among them, 1,040 (58.

Single stranded 1D-helical Cu coordination polymer for ultra-sensitive ammonia sensing at room temperature.

With the increasing demand for ammonia applications, there is a significant focus on improving NH detection performance at room temperature. In this study, we introduce a groundbreaking NH gas sensor based on Cu(I)-based coordination polymers, featuring semiconducting, single stranded 1D-helical nanowires constructed from Cu-Cl and -methylthiourea (MTCP). The MTCP demonstrates an exceptional response to NH gas (>900% at 100 ppm) and superior selectivity at room temperature compared to current materials.

The long-term effects of the fenestration in patients with extracardiac Fontan circulation-a multicenter Korean cohort study based on national Fontan registry.

Introduction: The long-term effects of fenestration in patients with Fontan circulation remain unclear. We aim to evaluate the fenestration impact on early and late outcomes in patients with extracardiac Fontan (ECF) using a propensity score matching analysis.

Methods: We performed an extensive retrospective multicenter clinical data review of the Korean Fontan registry and included 1,233 patients with surgical ECF (779 fenestrated, 454 non-fenestrated).

A combined extract containing (SCE) reduced hepatic triglyceride accumulation in rats fed a high-sucrose diet.

Unlabelled: Excessive hepatic lipid accumulation is closely linked to inflammation, insulin resistance, and metabolic syndromes. We hypothesized that a combined extract containing (SCE) could alleviate hepatic lipid accumulation. Male Sprague-Dawley rats fed a high-sucrose diet (HSD) were randomly assigned to three groups (n = 6): normal diet (ND), HSD (60% kcal from sucrose), and HSD + SCE (HSD with 2.

Using an influenza epidemic threshold different from those in the United States and Europe caused longer epidemic periods in Korea during the 2018-2019, 2019-2020, and 2022-2023 seasons: a comparative study.

Objectives: During the COVID-19 pandemic, the first seasonal influenza epidemic was declared in the 37th week of 2022 in Korea and has continued through the winter of 2023-2024. However, this finding has not been observed in the United States and Europe. The present study aimed to determine whether the prolonged influenza epidemic in Korea from 2022 to 2023 was caused by using a different influenza epidemic threshold compared to the thresholds used in the United States and Europe.

Low dead space encapsulation and integration of circuits for retinal prosthesis based on cyclic olefin copolymer.

A retinal prosthesis is a device that can provide artificial vision to people who have lost their sight from certain retinal disorder. Because the device needs to be inserted into the body, high flexibility and reliability is required. Recently, devices using thermoplastic polymers such as LCP and COC as substrates have been studied.

Fabrication of Implantable Microelectrode Array using Cyclic Olefin Copolymer and SU-8 via Photocrosslinking Lamination.

In this work, a fabrication process for implantable electrodes using a Cyclic Olefin Copolymer (COC) substrate and a SU-8 passivation layer was presented. COC and SU-8 were shown to be suitable for implantable neural electrodes due to their biocompatibility, chemical resistance, and thermal stability. The electrodes were successfully patterned on the COC film, and the SU-8 passivation layer was coated while maintaining site-opened via photolithography.

Dienogest in endometriosis treatment: A narrative literature review.

Endometriosis is characterized by the implantation of endometrial cells outside the uterus. This hormone-dependent disease is highly prevalent among women of reproductive age. Clinical symptoms of endometriosis include dysmenorrhea, pelvic pain, and infertility, which can negatively impact the overall quality of life of those affected.