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A retinal prosthesis is a device that can provide artificial vision to people who have lost their sight from certain retinal disorder. Because the device needs to be inserted into the body, high flexibility and reliability is required. Recently, devices using thermoplastic polymers such as LCP and COC as substrates have been studied. Being a highly functional integrated device, retinal prosthesis poses many design challenges. Among them, the stimulation chip embedding can be a particularly important task. Although it is common to use a wire bonding method for chip embedding, there are several limitations that are difficult to apply to implantable device. In this investigation, a novel approach is developed for high spaceefficient electrical connections and perform reliable encapsulation of integrated circuits to replace wire bonding. Since designing and manufacturing the stimulator chip used in retinal prosthesis requires non-negligible cost, a silicon die with the identical shape was selected as a substitute for testing purposes.
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http://dx.doi.org/10.1109/EMBC40787.2023.10341083 | DOI Listing |
J Neural Eng
September 2025
Hansen Experimental Physics Laboratory, Stanford University, 452 Lomita Mall, Stanford, California, 94305, UNITED STATES.
Clinical trials of the photovoltaic subretinal prosthesis PRIMA demonstrated feasibility of prosthetic central vision with resolution matching its 100 μm pixel width. To improve prosthetic acuity further, pixel size should be decreased. However, there are multiple challenges, one of which is related to accommodating a compact shunt resistor within each pixel that discharges the electrodes between stimulation pulses and helps increase the contrast of the electric field pattern.
View Article and Find Full Text PDFArch Orthop Trauma Surg
September 2025
Division of Orthopaedics and Traumatology, Cantonal Hospital Winterthur, Winterthur, Switzerland.
Background: Accurate acetabular cup orientation in total hip arthroplasty (THA) is crucial for successful outcomes. Intraoperative fluoroscopy may be used to evaluate acetabular cup placement. This study aimed to evaluate the accuracy of purely visual estimation of cup inclination and anteversion using intraoperative fluoroscopy, considering different surgeon experience levels and cup designs.
View Article and Find Full Text PDFJ Refract Surg
September 2025
The College of Medicine, Taibah University, Medina, Saudi Arabia.
Purpose: To present a case of synthetic intrastromal corneal ring segment (ICRS) intrusion secondary to necrosis and migration, managed by implantation of corneal allogenic intrastromal ring segments (CAIRS) within the preexisting tunnel.
Methods: A 24-year-old man with known keratoconus underwent bilateral ICRS implantation. He presented with blurred vision in the right eye 6 weeks after the procedure.
J Refract Surg
September 2025
Purpose: To evaluate tilt, decentration, and axial stability of the Clareon toric intraocular lens (TIOL) (CNW0T3-9; Alcon Laboratories, Inc) over a 6-month follow-up period.
Methods: A single-center, prospective, interventional clinical trial was conducted with a study population of 130 eyes from 82 patients who received a Clareon TIOL. Tilt, decentration, and the aqueous depth were determined preoperatively and at 1 week and 6 months postoperatively using anterior segment optical coherence tomography (Casia 2; Tomey Corporation).
Purpose: To evaluate visual and refractive outcomes, visual quality, patient satisfaction, and spectacle independence 3 months after phacoemulsification with bilateral non-diffractive enhanced depth of focus (EDOF) lens implantation.
Methods: This study included 68 eyes of 34 consecutive patients, with 51.5% undergoing refractive lens exchange and 48.