Publications by authors named "Joanna Chikwe"

Objective: Ventricular arrhythmias occur in a subset of patients with mitral valve prolapse. However, their impact on post-operative survival after degenerative mitral repair is unclear.

Methods: We compared long-term survival after degenerative mitral repair in patients presenting with and without arrhythmic mitral valve prolapse (defined by degenerative mitral regurgitation and ventricular arrhythmias) in a national insurance database.

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Objectives: Despite increased use of transcatheter aortic valve implantation (TAVI) in older adults with severe aortic stenosis, contemporary data on infective endocarditis (IE)-an infrequent but serious complication-are lacking. This study addresses this gap in knowledge.

Methods: We analysed 280 073 Medicare beneficiaries who underwent TAVI between 2013 and 2022.

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Objectives: Current guidelines recommend concomitant surgical ablation at the time of mitral surgery for patients with atrial fibrillation; however, there is a paucity of data on long-term outcomes in this population. We sought to assess long-term clinical outcomes in patients undergoing concomitant surgical ablation at the time of mitral surgery.

Methods: The United States Centers for Medicare and Medicaid data were used to identify patients undergoing mitral repair or replacement from 2015 to 2019.

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Objectives: Early and late outcomes of isolated tricuspid surgery in contemporary practice are poorly defined. This statewide analysis evaluated the early and late outcomes of isolated tricuspid repair and replacement.

Methods: From the Department of Health Care Access and Information of California State admissions database, 3706 patients who underwent isolated tricuspid repair (2419, 65.

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Background: The choice of bioprosthetic or mechanical surgical aortic valve replacement (AVR) should balance individual valve durability with the potential liabilities of oral anticoagulation.

Objectives: To inform clinical practice, this study sought to evaluate contemporary, real-world, long-term AVR outcomes from the Society of Thoracic Surgeons Adult Cardiac Surgery Database (STS ACSD).

Methods: All patients undergoing primary isolated bioprosthetic or mechanical AVR were identified.

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Background: Lung transplantation is performed through clamshell or sternotomy incisions, which may contribute to morbidity and limit patient eligibility. Robotic lung transplantation offers a less-invasive alternative, but data informing treatment choice are limited. This study was therefore designed to evaluate midterm outcomes of robotic and minimally invasive lung transplantation.

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Background: Controlled hypothermic preservation of donor hearts is associated with decreased post-transplant primary graft dysfunction compared to conventional cold storage. However, mechanisms underlying this benefit in human subjects are unclear.

Methods: We randomized 20 heart transplant recipients at a single institution to receive donor hearts preserved with either controlled hypothermic preservation or standard cold storage.

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Background: The role of prophylactic concomitant left atrial appendage closure during mitral repair in patients without atrial fibrillation (AF) is not defined.

Objectives: The objective was to compare long-term outcomes of patients who had left atrial appendage closure during mitral repair with those who did not in patients without AF.

Methods: A large national registry was used to identify 38,597 patients undergoing isolated mitral repair from 2010 to 2019.

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Background: Adoption of minimally invasive surgery (MIS) for early-stage non-small cell lung cancer (NSCLC) is increasing in the United States. We examined the relationship between sociodemographic factors and receipt of MIS among these patients.

Methods: Patients undergoing surgical resection for stage I and II NSCLC between 2010 and 2018 were identified in the National Cancer Database and stratified by surgical approach.

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Objective: The study objective was to characterize the trends and outcomes of aortic valve replacement in patients aged less than 65 years with aortic stenosis between 2013 and 2021.

Methods: This retrospective analysis included 9557 patients who underwent biological aortic valve replacement in California, New York, and New Jersey from 2013 to 2021. Patients were stratified by approach: transcatheter aortic valve replacement versus surgical aortic valve replacement.

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Article Synopsis
  • - Minimally invasive mitral valve repair techniques, including mini-thoracotomies and robotics, have greatly developed over the last 30 years, offering beneficial surgical options for patients.
  • - A study tracked 1,412 robotic mitral valve repairs from 2005 to 2023, showing significant improvements in surgical times and high repair success rates, particularly among patients treated by more experienced surgeons.
  • - Long-term results indicated a 92-93% survival rate at ten years and a very low rate of mitral regurgitation, demonstrating that robotic approaches provide effective and durable solutions for mitral valve issues.
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Background: Ex vivo lung perfusion (EVLP) may improve donor lung utilization but requires significant infrastructure and expertise. Centralized EVLP facilities may mitigate these requirements.

Methods: From the United Network for Organ Sharing database, we identified 345 adults undergoing isolated, first-time lung transplantation using donor lungs perfused by static EVLP (March 1, 2018-December 31, 2022).

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Background: Consensus guidelines recommend surgical aortic valve replacement (SAVR) over transcatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis aged ≤65 years. This analysis evaluates clinical practice and outcomes of TAVR and SAVR in patients aged ≤60 years.

Methods: We identified 2360 patients aged ≤60 years, including 523 TAVR (22.

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Article Synopsis
  • - The study analyzed outcomes of aortic repair techniques for descending thoracic aortic aneurysms (DTAAs) and thoracoabdominal aortic aneurysms (TAAAs) using data from The Society of Thoracic Surgeons Adult Cardiac Surgery Database, focusing on procedures from July 2017 to June 2022.
  • - Findings revealed that 85.2% of DTAA repairs were done endovascularly, while 66.9% of TAAA repairs were conducted through open surgery. Endovascular repairs showed lower rates of operative mortality, stroke, and spinal cord injury for both types of aneurysms compared to open repairs.
  • - The research suggested that differences in outcomes between the two surgical
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