Publications by authors named "Natalia Egorova"

Objective: Ventricular arrhythmias occur in a subset of patients with mitral valve prolapse. However, their impact on post-operative survival after degenerative mitral repair is unclear.

Methods: We compared long-term survival after degenerative mitral repair in patients presenting with and without arrhythmic mitral valve prolapse (defined by degenerative mitral regurgitation and ventricular arrhythmias) in a national insurance database.

View Article and Find Full Text PDF

Objectives: Despite increased use of transcatheter aortic valve implantation (TAVI) in older adults with severe aortic stenosis, contemporary data on infective endocarditis (IE)-an infrequent but serious complication-are lacking. This study addresses this gap in knowledge.

Methods: We analysed 280 073 Medicare beneficiaries who underwent TAVI between 2013 and 2022.

View Article and Find Full Text PDF

Objective: To determine if the route of administration of whole blood cardioplegia (cardioplegia) is significantly associated with the frequency of profound transient hypotension (intermittent "vasoplegia") often observed during cardioplegia administration.

Design: Retrospective analysis of automatically captured hemodynamic data from the electronic perfusion record (EPIC; Verona, WI).

Setting: A tertiary care academic medical center.

View Article and Find Full Text PDF

Objectives: This study aimed to compare vocal cord dysfunction (VCD) incidence between cardiac surgical and liver transplant (LT) patients and to assess associated anesthetic and surgical risk factors.

Design: A retrospective cohort study.

Setting: A single tertiary care hospital.

View Article and Find Full Text PDF

Background: We are studying whether the performance of the posterior quadratus lumborum block (pQLB) will decrease postoperative opioid consumption in patients undergoing laparoscopic sleeve gastrectomy (LSG) compared with surgical wound infiltration with local anesthetic.

Methods: This is a single-center, prospective, randomized pilot study. Forty ASA 3 patients with severe obesity undergoing LSG were randomized to receive either the pQLB or surgical wound infiltration of local anesthetics.

View Article and Find Full Text PDF

Objectives: Early and late outcomes of isolated tricuspid surgery in contemporary practice are poorly defined. This statewide analysis evaluated the early and late outcomes of isolated tricuspid repair and replacement.

Methods: From the Department of Health Care Access and Information of California State admissions database, 3706 patients who underwent isolated tricuspid repair (2419, 65.

View Article and Find Full Text PDF

Postreperfusion syndrome (PRS) is associated with complications following liver transplantation (LT). Mannitol may play a role in attenuating PRS as a free radical scavenger. This study aimed to evaluate the association between intraoperative mannitol administration and the incidence of PRS and postoperative acute kidney injury (AKI) in LT.

View Article and Find Full Text PDF

Objective: Postoperative delirium remains a common complication after cardiac surgery in high-risk patients and has been associated with prolonged intensive care unit length of stay, overall morbidity, and mortality. It has been proposed that cerebral hypoperfusion is an important etiological component. In the present study, we retrospectively queried intraoperative near-infrared spectroscopy measurements of regional cerebral oxygen saturations (rSO) during adult cardiac surgical procedures to examine the association between rSO desaturations and postoperative delirium.

View Article and Find Full Text PDF

Objective: Hemoconcentration and cell saver use are blood conservation techniques that are often used in cardiac surgery to salvage the patient's own blood to reduce autologous transfusion. The purpose of this study was to examine the perioperative outcomes including transfusion rates in cardiac surgical patients receiving hemoconcentrated blood versus cell saver blood via retrospective chart review. We hypothesized that hemoconcentration would have better patient outcomes, including reduced transfusion rates, compared to only cell salvage technique.

View Article and Find Full Text PDF

Background: Despite the widespread use of pulse oximetry for intraoperative estimation of arterial oxygen saturation, there is growing evidence that certain patient populations may be vulnerable to inaccurate pulse oximetry measurements and that unrecognized hypoxemia is associated with end-organ damage and adverse outcomes. In this single-center retrospective cohort study, we sought to better elucidate the relationship between intraoperative occult hypoxemia and postoperative mortality among patients undergoing anesthesia and surgery.

Methods: Data were collected from our departmental data warehouse for adult patients (≥18 years) undergoing anesthesia between 2008 and 2019 with at least 1 intraoperative arterial blood gas recorded.

View Article and Find Full Text PDF
Article Synopsis
  • Anesthetic gases are linked to global warming, prompting a project to analyze their carbon dioxide equivalent (CDE) production and fresh gas flows (FGF) in the operating room over two years.
  • In the second year, individualized feedback through a dashboard significantly reduced median FGF from 2.0 to 1.9 l/min and total CDE from 5.10 to 3.59 kg/hr (both p < 0.001).
  • The intervention resulted in notable reductions in CDE for isoflurane and nitrous oxide, leading to faster declines in their usage rates, although it showed no significant impact on sevoflurane or nitrous oxide CDE rates.
View Article and Find Full Text PDF

Objective: The study objective was to characterize the trends and outcomes of aortic valve replacement in patients aged less than 65 years with aortic stenosis between 2013 and 2021.

Methods: This retrospective analysis included 9557 patients who underwent biological aortic valve replacement in California, New York, and New Jersey from 2013 to 2021. Patients were stratified by approach: transcatheter aortic valve replacement versus surgical aortic valve replacement.

View Article and Find Full Text PDF

Objective: The objective of this study was to examine whether obesity without preexisting or gestational comorbidities is associated with postpartum hospital use (PHU).

Methods: We studied 2016 to 2018 birth certificate and discharge data on 178,729 New York City births without International Classification of Diseases, Tenth Revision (ICD-10) codes at delivery for diabetes; hypertension; placental disease; anemia; thyrotoxicosis; bariatric surgery; and pulmonary, cardiac, renal, bleeding, autoimmune, digestive, neuromuscular, mental, or substance-use disorders. We defined PHU as ≥1 readmission or emergency department visit within 30 days of delivery discharge.

View Article and Find Full Text PDF

Background: Racial and ethnic disparities in the treatment of perioperative pain have not been well-studied, despite being observed in a variety of other medical settings. The goal of this investigation was to evaluate the relationship between race and ethnicity and intra- and postoperative opioid administration for patients undergoing open liver resection surgery.

Methods: In this single-center retrospective cohort study, adult patients undergoing open liver resection from January 2012 to May 2019 were identified.

View Article and Find Full Text PDF

Background: Consensus guidelines recommend surgical aortic valve replacement (SAVR) over transcatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis aged ≤65 years. This analysis evaluates clinical practice and outcomes of TAVR and SAVR in patients aged ≤60 years.

Methods: We identified 2360 patients aged ≤60 years, including 523 TAVR (22.

View Article and Find Full Text PDF

Study Objective: To determine the association of practitioner dashboard feedback of intraoperative glycemic and temperature control on maintenance of normoglycemia and normothermia.

Design: Retrospective review.

Setting: Single tertiary care institution.

View Article and Find Full Text PDF
Article Synopsis
  • Malnutrition is often undiagnosed, leading to worse health outcomes and higher costs, prompting the Mount Sinai Health System to implement a machine learning model (MUST-Plus) for detection upon hospital admission.* -
  • The study analyzed data from nearly 67,000 adult patients to assess and improve the calibration of MUST-Plus, revealing significant miscalibration across different races and genders, particularly in its predictions.* -
  • After logistic recalibration, the model's accuracy improved for all patient subgroups, highlighting the importance of ongoing monitoring and adjustment to reduce healthcare disparities.*
View Article and Find Full Text PDF

Importance: The use of valve-in-valve (ViV) transcatheter aortic valve replacement (TAVR) has been rapidly expanding as an alternative treatment to redo surgical aortic valve replacement (SAVR) for failed bioprosthetic valves despite limited long-term data.

Objective: To assess mortality and morbidity in patients undergoing intervention for failed bioprosthetic SAVR.

Design, Setting, And Participants: This was a retrospective population-based cohort analysis conducted between January 1, 2015, and December 31, 2020, with a median (IQR) follow-up time of 2.

View Article and Find Full Text PDF

Importance: The Joint Commission Unexpected Complications in Term Newborns measure characterizes newborn morbidity potentially associated with quality of labor and delivery care. Infant exclusions isolate relatively low-risk births, but unexpected newborn complications (UNCs) are not adjusted for maternal factors that may be associated with outcomes independently of hospital quality.

Objective: To investigate the association between maternal characteristics and hospital UNC rates.

View Article and Find Full Text PDF
Article Synopsis
  • Tricuspid valve annuloplasty (TA) during mitral valve repair (MVr) increases the risk of needing a permanent pacemaker (PPM) post-surgery, with a higher 90-day PPM implantation rate for MVr with TA (14.0%) compared to isolated MVr (7.7%).
  • This study analyzed data from New York and California between 2004 and 2019 to evaluate the long-term effects of PPM implantation on survival and complications like heart failure hospitalization and endocarditis.
  • Results indicated that PPM recipients had significantly reduced long-term survival and higher risks of heart failure hospitalizations and endocarditis, regardless of whether they underwent isolated MVr or MVr with TA.
View Article and Find Full Text PDF

Objective: Limited comparative data guide the decision between coronary artery bypass grafting and percutaneous coronary intervention for multivessel revascularization in ischemic cardiomyopathy. The study objective was to compare the long-term outcomes of coronary artery bypass grafting and percutaneous coronary intervention for ischemic cardiomyopathy.

Methods: Clinical registries from the New Jersey Department of Health linked to administrative databases were used to compare all-cause mortality, repeat revascularization, heart failure readmissions, myocardial infarction, and stroke using Cox proportional hazards and propensity matching with competing risk analysis in 5988 patients with ejection fraction 35% or less who underwent coronary artery bypass grafting (3673, 61.

View Article and Find Full Text PDF

Introduction: Right-side infective endocarditis (RSIE) is caused by microorganisms and develops into intracardiac and extracardiac complications with high in-hospital and 1-year mortality. Treatments involve antibiotic and surgical intervention. However, those presenting with extremes e.

View Article and Find Full Text PDF

Background: Myocardial recovery occurs in patients with advanced heart failure on left ventricular assist device (LVAD) support, but there is the premise that it is rare with uncertain results.

Objectives: The goal of this study was to investigate the incidence and consequence of LVAD explant after myocardial recovery.

Methods: Using the United Network for Organ Sharing registry, LVAD implants in the United States between 2005 and 2020 were tracked until death, transplantation, or explant for myocardial recovery.

View Article and Find Full Text PDF

Background: Current guidelines recommend revascularization in patients with ischemic cardiomyopathy (ICM). However, there is limited information about the trends and outcomes of coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in ischemic cardiomyopathy patients with multivessel coronary artery disease.

Methods And Results: Using New Jersey state mandatory registries, 8083 patients with ischemic cardiomyopathy with CABG or PCI revascularization for multivessel coronary artery disease from 2007 to 2018 were included in the analysis.

View Article and Find Full Text PDF