Can resident registration expiration statistics due to death be used for near-real-time mortality tracking? A validation study using 2023 data from South Korea.

Objectives: Real-time mortality tracking is essential for public health surveillance, especially during emergencies such as the COVID-19 pandemic. In South Korea, delayed availability of Vital Statistics (VS) data has hindered timely mortality monitoring. This study evaluates whether National Administrative Data (NAD) on resident registration expiration due to death, provided by the Ministry of Interior and Safety (MOIS), could serve as a reliable alternative for near real-time mortality surveillance.

Evaluation of the accuracy of a 3D-printed palatal auxiliary device for maxillary protraction after palatal expansion.

Objective: This study aimed to evaluate the accuracy of a three-dimensional (3D)-printed palatal auxiliary device (PAD) compared to computer-aided design (CAD) reference data.

Methods: Thirty patients who underwent orthodontic treatment using a PAD for maxillary protraction after palatal expansion were included in this study. Two groups of 15 patients were analyzed to compare the accuracy of the two PAD designs.

The Predestined Failure of the Market Mechanism in Ensuring Health for all in Times of a Pandemic: The Case of the Republic of Korea.

This article investigated South Korea's COVID-19 response through the lens of power relations, arguing that the state's overreliance on public health measures stemmed from its inability to control economic power within the medical care sector. By applying a modified version of Erik Olin Wright's theoretical framework, the study examines interactions between state, economic, and social powers across two distinct economies: public health and medical care policies. The analysis reveals that insufficient state and social power to regulate economic power in medical care necessitated stricter public health interventions.

The impact of a medical residents' walkout on mortality rates in South Korea, 2024.

Background: At the end of February 2024, over 11,000 medical residents in South Korea collectively resigned in opposition to the government's policy to increase medical school admissions, raising widespread concerns about potential health consequences amid prolonged workforce shortages in acute hospitals.

Objective: To assess the impact of the medical residents' walkout on mortality rates in South Korea during 2024.

Methods: We conducted a retrospective observational study using mortality data from Statistics Korea's Vital Statistics (2019-2023) and the Ministry of Interior and Safety's Registration Expiration Statistics (2024).

Long-acting injectable delivery system comprising ordered mixed drug aggregates with deaggregating and uniformly embeddable viscoelastic -polysaccharide solutions.

This study aimed to construct a ready-to-use, two-syringe mixing (TM) system comprising free-flowing drug aggregates with deaggregating and uniformly embeddable polysaccharide solutions as a new approach for long-acting parenteral delivery. Rotigotine (RG) and donepezil (DP), approved for the treatment of Parkinson's and Alzheimer's diseases, respectively, were employed as model compounds. For syringe filling, free-flowing drug aggregates were engineered using ordered mixing, adhering pulverized RG (1.

Lightweight Pre-Trained Korean Language Model Based on Knowledge Distillation and Low-Rank Factorization.

Natural Language Processing (NLP) stands as a forefront of artificial intelligence research, empowering computational systems to comprehend and process human language as used in everyday contexts. Language models (LMs) underpin this field, striving to capture the intricacies of linguistic structure and semantics by assigning probabilities to sequences of words. The trend towards large language models (LLMs) has shown significant performance improvements with increasing model size.

Measuring the paraspinal muscles as an important tool for predicting the overall survival period after spine surgery in lung cancer patients with spine metastasis.

Study Design: Retrospective cohort study BACKGROUND: Metastatic lung cancer in the spine is difficult to determine whether to perform an additional surgical intervention, as patients at the end stage of lung cancer often have low performance status with significant muscle atrophy. This study aimed to demonstrate whether sarcopenia affects the prognosis after spine surgery in lung cancer patients by measuring the paraspinal muscles.

Methods: A total of 65 lung cancer patients who underwent spine surgery were reviewed.

Effectiveness of intradiscal steroid injection for spinal stenosis: a retrospective cohort study in South Korea.

Study Design: A retrospective cohort study.

Purpose: This study aimed to evaluate the efficacy of intradiscal steroid injection (ISI) in managing patients with spinal stenosis.

Overview Of Literature: ISI has shown effectiveness in relieving lower back pain in patients with degenerative disc disease.

Novel radiologic parameter for assessing decompression adequacy in anterior cervical decompression surgery: the V-line.

Background Context: Anterior cervical decompression surgeries, such as Vertebral Body Sliding Osteotomy (VBSO) and Anterior Cervical Corpectomy and Fusion (ACCF), serve as vital surgical options for managing cervical myelopathy. Despite their effectiveness, incomplete expansion of the spinal canal can occur in certain cases. However, many patients still experience positive clinical outcomes after these surgeries, suggesting that assessing outcomes based solely on the lesion's canal-occupying effect may be limited.

Critical factors in enhancing the correction efficacy for varus talar tilt in patients with varus ankle osteoarthritis: relative fibular shortening to the tibia and syndesmotic widening.

Introduction: Relative fibular shortening compared to the tibia and syndesmotic widening are recognized contributors to the valgus tilt of the talus. This study aimed to assess: (1) the impact of fibular shortening relative to the tibia; and (2) the influence of syndesmotic widening, in correcting a large varus talar tilt (TT) associated with advanced ankle osteoarthritis through medial opening wedge valgization supramalleolar osteotomy (SMO).

Materials And Methods: We retrospectively reviewed the clinico-radiographic findings of 41 patients with a preoperative TT of 8 degrees or more who underwent SMO for varus ankle osteoarthritis, with a minimum follow-up of more than two years.

SON is an essential RNA splicing factor promoting ErbB2 and ErbB3 expression in breast cancer.

Background: In breast cancer, ErbB receptors play a critical role, and overcoming drug resistance remains a major challenge in the clinic. However, intricate regulatory mechanisms of ErbB family genes are poorly understood. Here, we demonstrate SON as an ErbB-regulatory splicing factor and a novel therapeutic target for ErbB-positive breast cancer.

Optimized method development and validation for determining donepezil in rat plasma: A liquid-liquid extraction, LC-MS/MS, and design of experiments approach.

Donepezil (DPZ), a piperidine-based reversible cholinesterase inhibitor, finds extensive use in treating Alzheimer's disease (AD). Originally designed as an oral formulation, DPZ encounters drawbacks such as a brief duration of action and reduced treatment effectiveness in elderly patients with memory impairment or difficulty swallowing medications. To address these issues and improve patient compliance, researchers are actively exploring alternative DPZ formulations.

Carboxymethyl cellulose-based rotigotine nanocrystals-loaded hydrogel for increased transdermal delivery with alleviated skin irritation.

Transdermal rotigotine (RTG) therapy is prescribed to manage Parkinson's disease (Neupro® patch). However, its use is suffered from application site reactions. Herein, drug nanocrystalline suspension (NS)-loaded hydrogel (NS-HG) employing polysaccharides simultaneously as suspending agent and hydrogel matrix was constructed for transdermal delivery, with alleviated skin irritation.

Angioinvasive Mucormycosis Mimicking Mass and Pulmonary Thromboembolism in a Patient with Myelodysplastic Syndrome: A Case Report.

Mucormycosis encompasses a range of fungal infections that can impact various organs. Although pulmonary mucormycosis is relatively rare, it poses a significant threat, particularly to individuals with compromised immune systems. Pulmonary mucormycosis presents with various radiological manifestations.

Antenatal care inequalities in South Korea: An analysis of health insurance claims data (2013-2022) in a high-resource, high-use country.

Objective: The aim of the present study was to explore inequalities in antenatal care (ANC) in South Korea. Based on the guidelines of the WHO, we categorized less than eight visits to an obstetrical facility as insufficient ANC. We examined ANC inequalities associated with age, disability, nationality, income, and geographic accessibility.

Assessing the impact and implications of the revised Act on the Aggravated Punishment of Specific Crimes in preventing child traffic injuries in school zones in Korea: an interrupted time series analysis.

In 2019, a child's death in Korea led to legislation that imposed stricter penalties for school zone traffic violations. We assessed the impact of that legislation using 2017-2022 Traffic Accident Analysis System data. Adjusted analyses revealed a significant decline in severe injuries in school zones, decreasing from 11 cases to 8 cases per month (p=0.

Comparison of Partial Versus Superficial or Total Parotidectomy for Superficial T1-2 Primary Parotid Cancers.

Objectives: This study aimed to compare the oncological outcomes of partial versus superficial or total parotidectomy for superficial T1 or T2 primary parotid cancers and investigate their prognostic factors and recurrence patterns.

Methods: The medical records of 77 patients with T1-2 primary parotid malignancies between May 2003 and March 2022 were retrospectively reviewed. Univariate and multivariate analyses were performed to evaluate the prognostic factors associated with overall survival, disease-free survival, and local and distant recurrence.

Development and Validation of a Robust and Interpretable Early Triaging Support System for Patients Hospitalized With COVID-19: Predictive Algorithm Modeling and Interpretation Study.

Background: Robust and accurate prediction of severity for patients with COVID-19 is crucial for patient triaging decisions. Many proposed models were prone to either high bias risk or low-to-moderate discrimination. Some also suffered from a lack of clinical interpretability and were developed based on early pandemic period data.

Connecting the S2 alar-iliac screw head to the satellite rod for surgical correction of degenerative sagittal imbalance.

Purpose: The S2AI screw technique has several advantages over the conventional iliac screw fixation technique. However, connecting the S2AI screw head to the main rod is difficult due to its medial entry point. We introduce a new technique for connecting the S2AI screw head to a satellite rod and compare it with the conventional method of connecting the S2AI screw to the main rod.

Current Trends in Artificial Intelligence-Assisted Spine Surgery: A Systematic Review.

This systematic review summarizes existing evidence and outlines the benefits of artificial intelligence-assisted spine surgery. The popularity of artificial intelligence has grown significantly, demonstrating its benefits in computer-assisted surgery and advancements in spinal treatment. This study adhered to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), a set of reporting guidelines specifically designed for systematic reviews and meta-analyses.

[Primary Malignant Peripheral Nerve Sheath Tumor of the Pulmonary Vein: A Case Report].

Primary masses rarely originate from the heart and great vessels, and a malignant peripheral nerve sheath tumor (MPNST) is extremely rare. A 76-year-old male with pleural effusion underwent contrast-enhanced computed tomography, which revealed a hypoattenuating mass involving the right pulmonary vein and left atrium. Ultrasonography showed that the mass originated from the right pulmonary vein.

Insidious Onset Multifocal Chest Wall and Spinal Abscess Caused by Previous Candidemia: A Case Report.

Abscess formation due to infection is extremely rare. Radiological diagnosis of an atypical abscess at an uncommon site is challenging. In this study, we present a case of insidious onset multifocal chest wall and spinal abscess after candidemia in a young woman in the intensive care unit due to postpartum bleeding.