Predictors of early resistance to catheter-directed thrombolysis in patients with proximal deep vein thrombosis.

Purpose: To determine predictors of immediate thrombolysis resistance (iTR) in patients with proximal deep vein thrombosis (DVT), defined as thrombosis involving the femoral or more proximal veins, with or without concomitant popliteal vein involvement, and to investigate its impact on long-term post-thrombotic syndrome (PTS) outcomes.

Methods: This single-center retrospective study reviewed consecutive patients who underwent catheter-directed thrombolysis (CDT) as first-line therapy. Baseline demographics, clinical history, comorbidities and provoking risk factors for DVT, intraprocedural findings, periprocedural complications, and follow-up outcomes were compared between the iTR and immediate thrombolysis success (iTS) groups.

A predictive model for early detection of concomitant pulmonary embolism in patients with deep vein thrombosis immediately upon hospital admission.

Objective: To develop and validate a predictive model for the early identification of concomitant pulmonary embolism (PE) in patients with deep vein thrombosis (DVT) upon hospital admission.

Methods: We retrospectively collected data from a cohort of patients diagnosed with DVT, including baseline demographics, clinical characteristics, laboratory parameters, and imaging-based measurements of compression of the iliac vein to develop a predictive model. The least absolute shrinkage and selection operator regression, widely used in clinical decision-making algorithms for its ability to perform variable selection and regularization simultaneously, was used for variables selection.

Radial Support Force: A Key Player in Vena Cava Neointimal Hyperplasia.

Background: Neointimal hyperplasia (NIH) is a risk factor for inferior vena cava filter (IVCF) retrieval failures and damage to the inferior vena cava (IVC) wall post-retrieval. Unfortunately, the mechanical properties of IVCFs have not been evaluated and are not readily available from the manufacturer. This study aimed to investigate the correlations between radial support force (RSF) and NIH, and the release of tumor necrosis factor-alpha (TNF-α) during this process.

Percutaneous mechanical thrombectomy versus catheter-directed thrombolysis for the treatment of arterial acute mesenteric ischemia and risk factors for 30-day mortality.

Objective: To compare the efficacy and safety outcomes between percutaneous mechanical thrombectomy (PMT) and catheter-directed thrombolysis (CDT) as the first endovascular revascularization (EVR) strategy for arterial acute mesenteric ischemia (AMI) and identify risk factors for 30-day mortality.

Methods: This was a single-center retrospective study. Between May 2014 and March 2024, consecutive patients with arterial AMI who received EVR using PMT or CDT as the first strategy were included.

Association of computed tomography-imaged common iliac vein compression with inferior vena cava thrombosis: a propensity score-matched analysis.

Background: Investigating the association between common iliac vein (CIV) compression and inferior vena cava (IVC) thrombosis could have important clinical implications, such as a potential reduction in the use of IVC filters in low-risk patients and guidance for decision-making in thrombosis management. This study aimed to clarify the impact of the CIV compression degree on the incidence of IVC thrombosis in patients with lower extremity deep vein thrombosis (DVT).

Methods: This single-center, retrospective study was performed between January 2015 and July 2023.

Unveiling the link between oversizing ratio and neointimal hyperplasia in a porcine model.

Intimal hyperplasia (IH) is a major risk for inferior vena cava (IVC) filter retrieval failures and potentially fatal vascular trauma to the IVC or caudal vena cava (CVC) wall post-retrieval. However, demonstrating neointimal formation in humans presents challenges due to the difficulty in obtaining quantitative pathological evidence from the IVC. Here, it was hypothesized that the mismatch between the diameter of the CVC and the filter would correlate with increased IH.

Radiographic Characterization of Inferior Vena Cava and Its Reaction Following Filter Placement: A Single-Center Retrospective Study.

Objective: To classify the radiographic characterization of the inferior vena cava (IVC) diameter, as well as to quantitatively describe the dimensional alternations in response to variations in filter placement, using cross-sectional computer tomographic venography (CTV) imaging.

Methods: A single-center retrospective study was conducted on eligible patients who underwent CTV of IVC both before and after the placement of spindle-shaped filters, from September 2018 to June 2023. Baseline data, IVC diameter and orientation and -filter placement, IVC enlargement rate, and related complications were analyzed.

Relationship Between Left Moderate or Severe Common Iliac Vein Compression and Occurrence of Involved Iliac Vein Thrombosis in Patients with Infrainguinal Deep Vein Thrombosis.

Purpose: To investigate the association between the degree of common iliac vein (CIV) compression and the incidence of iliac vein involvement thrombosis (IVT) in patients with infrainguinal deep vein thrombosis (DVT).

Methods: This was a single center retrospective study. Between January 2015 and July 2023, infrainguinal DVT patients with or without IVT were included.

Deciphering the role of cuproptosis in the development of intimal hyperplasia in rat carotid arteries using single cell analysis and machine learning techniques.

Unlabelled: This study aims to explore the regulatory role of cuproptosis in carotid intimal hyperplasia (IH), providing new insights into its pathophysiological mechanisms and potential diagnostic and therapeutic strategies.

Methods: We downloaded single-cell sequencing and bulk transcriptome data from the GEO database to screen for copper-growth-associated genes (CAGs) using machine-learning algorithms, including Random Forest and Support Vector Machine. After identifying relevant genes, we verified CAGs expression in IH and control groups using a rat model of carotid balloon strain.

Endovascular Coiling Combined With Tissue Glue Embolism to Treat 20 Cases of Iliac Arteriovenous Fistula Secondary to Deep Vein Thrombosis.

Objective: The objective of this study is to assess the feasibility of endovascular coiling combined with tissue glue embolism for the treatment of iliac arteriovenous fistula (AVF) secondary to deep vein thrombosis (DVT) of the lower extremities. In addition, we aim to summarize the treatment methods and enhance understanding of the disease.

Methods: This research analyzes the clinical data and medical imaging materials of 20 cases with iliac AVF secondary to lower extremity DVT, ranging from December 2014 to December 2020, at our hospital.

HSYA ameliorates venous thromboembolism by depleting the formation of TLR4/NF-κB pathway-dependent neutrophil extracellular traps.

Neutrophil extracellular traps (NETs), released by activated neutrophils, are implicated in various medical conditions, including venous thromboembolism (VTE). To develop effective therapeutic strategies for VTE, it is crucial to elucidate the mechanisms involved. In this study, we explored the role of NETs in VTE pathogenesis and assessed the impact of hydroxyl safflower yellow pigment A (HSYA) treatment on VTE pathogenesis.

Efficacy and safety of a novel vena cava filter on pulmonary embolism prophylaxis: a prospective, multicenter, randomized, parallel, positive-controlled, noninferiority clinical trial.

Background: There are different types of vena cava filter (VCF) available in clinical practice. However, limited data exist to determine whether one type is superior to another, and no single VCF is universally recommended in clinical guidelines. The objective of this study was to investigate the safety and efficacy of a novel VCF, Octoparms, for the prevention of pulmonary embolism (PE) and to compare it with the Celect filter.

Experimental Study on Penetration of Smaller Inferior Vena Cava after Conical Filter Placement: Results in a Swine Model.

Objectives: Inferior vena cava (IVC) penetration is a prevalent complication following the placement of conical filters. However, there is a paucity of studies examining the penetration in smaller IVC. The objective of this study was to assess the time of penetration, the incidence of serious complications associated with penetration, and the process of IVC wall repair in the smaller IVC following the placement of a conical filter.

Endovascular revascularization vs open surgical revascularization as the first strategy for arterial acute mesenteric ischemia: A systematic review and meta-analysis.

Objective: This paired meta-analysis aimed to compare the mortality and morbidity of endovascular revascularization (EVR) and open surgical revascularization (OSR) as the first strategy for arterial acute mesenteric ischemia (AMI).

Methods: This systematic review and meta-analysis were performed in accordance with the PRISMA statement. A systematic search strategy was performed to identify eligible studies using the following databases: PubMed, Embase, and Cochrane Library database from inception to December 31, 2023, with restriction to the English language.

Establishment of an acute arterial mesenteric ischaemia model in canines with an endovascular approach.

Purpose: This study aimed to evaluate the feasibility of establishing an arterial acute mesenteric ischemia (AMI) model in canines using transcatheter autologous thrombus administration.

Materials And Methods: Ten canines were divided into the experimental group (Group A,  = 5) and the sham group (Group B,  = 5). The canines in Group A received thrombus administration to the superior mesenteric artery (SMA) through a guiding catheter, while the canines in Group B received normal saline administration.

Green recovery in the wake of public health emergencies: Policy instruments and their effects in China.

Numerous studies have discussed the economic impacts of the COVID-19 pandemic in recent years. However, the effectiveness and trade-offs of diverse countermeasures still need to be investigated, particularly under the long-term goal of low-carbon transition, which is crucial for understanding the potential impacts of the future public health emergency (PHE) related economic crisis. Given that China still faces big pressures from the potential PHE and carbon neutrality, this paper assesses the effectiveness of policy instruments in restoring the economy and advancing green development after the PHE using the Dynamic Stochastic General Equilibrium framework.

Research on urban economic centrality in the perspectives of knowledge stocks and flows.

In light of the profound advancements in information and communication technologies ushering in the knowledge economy, the urban space is undergoing a transformation from the traditional "space of places" to the emerging "space of flows." This shift poses questions about the influence of knowledge flows on urban economic centrality. This paper seeks to address this knowledge gap by introducing a theoretical framework that elucidates how knowledge contributes to urban economic centrality.