Publications by authors named "Jianjun Bian"
Acquired hemophilia A secondary to cholangiocarcinoma: A case report and literature review.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
February 2025
Acquired hemophilia A (AHA) is a rare autoimmune bleeding disorder. Its occurrence secondary to hepatobiliary malignancies is even rarer, and without timely diagnosis and treatment, the mortality rate is extremely high. There is a need to raise awareness of this disease.
View Article and Find Full Text PDFObjective: The aim of this study was to explore the efficacy and safety of azacitidine (AZA) in middle-aged and elderly patients with myelodysplastic syndrome (MDS).
Methods: The clinical data of 59 middle-aged and elderly patients with middle- and high-risk MDS, who attended our hospital from April 2019 to January 2024, were retrospectively analyzed and were divided into an observation group (AZA) and a control group (conventional supportive treatment) according to the treatments, and the patients in the two groups were evaluated for their clinical efficacy and safety.
Results: The overall response rate of the observation group was 66.
Article Synopsis
- High-strength aluminum alloys are typically limited to low temperatures (below ~150 °C), but there’s a need for alloys that can perform in the 300‒400 °C range for lightweight design and energy applications.* -
- Research demonstrates a new strategy using interstitial solutes in Sc-added Al-Cu-Mg-Ag alloys to create stable nanoprecipitates (V phase) that significantly improve creep resistance and tensile strength at higher temperatures (~100 MPa at 400 °C).* -
- The formation of these stable V phase nanoprecipitates is facilitated by a unique phase transformation process that helps to harmonize the interactions between slow-diffusing and fast-diffusing atoms, suggesting potential for large
Freezing solute atoms in nanograined aluminum alloys via high-density vacancies.
Nat Commun
June 2022
Low-temperature decomposition of supersaturated solid solution into unfavorable intergranular precipitates is a long-standing bottleneck limiting the practical applications of nanograined aluminum alloys that are prepared by severe plastic deformation. Minimizing the vacancy concentration is generally regarded as an effective approach in suppressing the decomposition process. Here we report a counterintuitive strategy to stabilize supersaturated solid solution in nanograined Al-Cu alloys via high-density vacancies in combination with Sc microalloying.
View Article and Find Full Text PDFArticle Synopsis
- * At lower hydrogen levels (0-0.3), dislocations form under surface steps, while higher levels (0.3-0.4) introduce defects that alter dislocation behavior and prevent typical formations like pyramid hillocks.
- * For hydrogen content between 0.4-0.5, recoverable phase transitions start influencing plastic deformation, providing new insights into how hydrogenation affects Pd nanoparticle mechanics.
Abrupt elastic-to-plastic transition in pentagonal nanowires under bending.
Beilstein J Nanotechnol
December 2019
In this study, pentagonal Ag and Au nanowires (NWs) were bent in cantilever beam configuration inside a scanning electron microscope. We demonstrated an unusual, abrupt elastic-to-plastic transition, observed as a sudden change of the NW profile from smooth arc-shaped to angled knee-like during the bending in the narrow range of bending angles. In contrast to the behavior of NWs in the tensile and three-point bending tests, where extensive elastic deformation was followed by brittle fracture, in our case, after the abrupt plastic event, the NW was still far from fracture and enabled further bending without breaking.
View Article and Find Full Text PDFArticle Synopsis
- The study uses molecular dynamic simulations to explore how twinned nanospheres respond to compression, focusing on the relationship between the applied load and deformation depth.
- It examines how different twin spacing and loading directions affect the elastic properties and plastic deformation mechanisms of the nanospheres.
- The findings reveal that twin boundaries strengthen the nanospheres by obstructing dislocation movement, with the effectiveness of this strengthening highly influenced by the distance between the twin boundaries.