Surface modification of implant materials continues to address the issue of osseointegration. Moreover, combining osseointegration with bactericidal or antifouling properties in implants remains an open question for debate. Over the years, silver has been widely used as an agent for killing and preventing bacterial proliferation.
View Article and Find Full Text PDFBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
May 2025
Increasingly complex and patient-specific healthcare requires new approaches to the qualification of future specialists, with interprofessionalism and cooperation between the healthcare professions becoming more and more important. In order for the various professions to work well together in everyday working life, it is essential to learn this interprofessionalism during training. The subject of clinical pharmacy as "patient-oriented pharmacy" aims to optimize patient medication and drug therapy safety and thus to improve the health and quality of life of patients.
View Article and Find Full Text PDFUsing network representations of the lexicon has expanded our understanding of vocabulary growth processes and vocabulary structure during early development. These models of vocabulary development have used multiple types of sources to create lexical representations. More recently, Weber and Colunga (2022) demonstrated that predictions of early vocabulary norms can be improved by using network representations based on a corpus incorporating language a young child might typically hear.
View Article and Find Full Text PDFMachine perfusion (MP) is gaining importance in liver transplantation, the only cure for many end-stage liver diseases. Varieties of different MP protocols are available. Currently, various MP protocols are available, differing not only in perfusion temperature but also in the specific perfusion solution required.
View Article and Find Full Text PDFInt J Speech Lang Pathol
November 2024
Purpose: This study explored the feasibility of implementing an individualised vocabulary intervention for dual language learners through teachers, who leverage their knowledge about their students to address each child's diverse needs.
Method: Participants were 32 Cantonese-English pre-school dual language learners and 16 teacher implementers from eight classrooms of a Head Start Programme. During the 3-week programme, teacher implementers were given an individualised set of 12 target words for each student.
Front Med (Lausanne)
October 2023
Introduction: Hemoadsorption shows promising signals in organ preservation and post lung transplantation. However, its potential impact on the pharmacokinetics of immunosuppressant drugs (ID) is still unknown.
Methods: In this interventional study, CytoSorb® hemoperfusion was tested in healthy sheep ( = 5) against a sham extracorporeal circuit ( = 3).
Unilateral lung agenesis is a rare congenital abnormality that typically presents with respiratory distress after birth. Prognostic factors include the side of the lung affected along with the presence or absence of other congenital abnormalities. Prenatal imaging can make the diagnosis that can assist the healthcare team in preparing to care for the neonate, as well as set expectations for the family.
View Article and Find Full Text PDFSuccessful uterus transplantation, a potential treatment method for women suffering from absolute uterine infertility, is negatively affected by ischemia-reperfusion injury (IRI). The aim of this study is to investigate the protective effect of relaxin (RLX) or/and erythropoietin (EPO) on experimental uterus IRI. Eighty rats, randomly assigned into eight groups ( = 10/group), were pretreated with either saline, 5 μg/kg human relaxin-2, 4000 IU/kg recombinant human erythropoietin or their combination.
View Article and Find Full Text PDFBehav Anal Pract
March 2022
This study evaluated the effectiveness of the AIM curriculum when implemented in a public-school setting by schoolteachers and direct care staff. Three hundred eighteen students took part in this quasiexperimental design where all received the AIM curriculum every day for an entire school year. The participants completed a series of self-assessments (the Avoidance and Fusion Questionnaire for Youth, the Child and Adolescent Mindfulness Measure, and the Strength and Difficulties Questionnaire) at the onset of the study and at the end of the school year to assess psychological flexibility, mindfulness, and emotional behavioral skills.
View Article and Find Full Text PDFIschemia-reperfusion injury (IRI) is inevitable after kidney transplantation (KT), impairing outcomes. Relaxin-2 (RLX) is a promising insulin-related peptide hormone that protects against renal IRI in rodents, although large animal models are needed before RLX can be tested in a human setting. In this blinded, randomized, and placebo-controlled experimental study kidneys from 19 donor pigs were retrieved after perfusion with Custodiol ± RLX (5 or 20 nmol/L) and underwent static cold storage (SCS) for 24 and 48 h, respectively.
View Article and Find Full Text PDFObjective: The study aimed to evaluate the validity of transcutaneous bilirubin (TcB) measurements at three sites in premature infants born at 23 to 34 weeks' gestational age (GA) compared with total serum bilirubin (TSB) measurements.
Study Design: A prospective study was conducted at Banner - University Medical Center Phoenix, where informed consent was obtained from the infant's parent or legally authorized representative. Cohort A was comprised of infants 23 to 28 weeks' GA and Cohort B contained subjects 29 to 34 weeks' GA.
Aims: In 2017, the Child and Adult Care Food Program (CACFP), which reimburses qualifying food expenses for Family Child Care Home (FCCH) providers, was substantially enhanced. This study's purpose was to explore the perceptions of Oklahoma FCCH providers of these enhancements and to determine current meal practices as an opportunity to foster collaborations between educators, service providers, and health and nutrition professionals.
Methods: This mixed-methods study included a cross-sectional survey (n=30) and semi-structured interviews (n=30) and menu analysis (n=25) of FCCH providers participating in the CACFP.
Telemed J E Health
June 2021
Video visits, or televisits, have become increasingly popular across various medical subspecialties. Within the University of California, Davis, Neonatal Intensive Care Unit, a video visitation program known as FamilyLink allows families to remotely view their babies when they are otherwise unable to visit. This study aimed to explore parents' perceived effects of video camera use as well as the relationship of video visit use with rates of breast milk feedings at hospital discharge.
View Article and Find Full Text PDFRheumatology (Oxford)
February 2021
Objective: To investigate peripheral lymphopenia, a frequent finding in primary Sjögren's syndrome (pSS) associated with higher disease activity and increased mortality.
Methods: Prospective, cross-sectional study of consecutive patients with pSS (n = 66) and healthy controls (n = 181). Lymphocyte subsets were analysed by flow cytometry, naïve (CD45RA+) and memory (CD45RO+) CD4+ T cells were purified by MACS technology.
Premise: Understanding species' responses to climate change is a critical challenge facing biologists today. Though many species are widespread, few studies of climate-driven shifts in flowering time have examined large continuous spatial scales for individual species. And even fewer studies have examined these shifts at time scales greater than a few decades.
View Article and Find Full Text PDFBackground: Early childhood is a critical period of development. Caregivers, including providers of early care and education (ECE), have a substantial influence on the health of young children. Family child care homes (FCCHs), which are small, licensed ECE businesses operated out of the residences of providers, are important settings for promoting child health.
View Article and Find Full Text PDFWithin riverine systems, headwater populations are hypothesized to harbour higher amounts of genetic distinctiveness than populations in the main stem of a river and display increased genetic diversity in large, downstream habitats. However, these hypotheses were mostly developed with insects and fish, and they have not been tested on many invertebrate lineages. Pleuroceridae gastropods are of particular ecological importance to rivers of eastern North America, sometimes comprising over 90% of macroinvertebrate biomass.
View Article and Find Full Text PDFPlant breeding systems can vary widely among populations, yet few studies have investigated abiotic factors contributing to variation across a broad geographic range. Here we investigate variation in reproductive traits of (Campanulaceae), a species that exhibits dimorphic cleistogamy, a condition in which individual plants have both closed (selfing: cleistogamous: CL) and open (selfing or outcrossing: chasmogamous: CH) flowers. Chasmogamous production is theorized to be more costly because CH flowers have a larger exposed surface area and thus are more likely to lose more water than CL flowers.
View Article and Find Full Text PDFPremise Of Study: In a seminal body of theory, Lloyd showed that the fitness consequences of selfing will depend on its timing in anthesis. Selfing that occurs after opportunities for outcrossing or pollen dispersal can provide reproductive assurance when pollinators are limited and is expected to incur little cost, even when inbreeding depression is high. As a result, delayed selfing is often interpreted as a "best-of-both-worlds" mating system that combines the advantages of selfing and outcrossing.
View Article and Find Full Text PDFObjective: To evaluate the impact of a pilot intervention for physicians to support their treatment of patients at risk for opioid abuse.
Setting, Design And Patients, Participants: Patients at risk for opioid abuse enrolled in Medicare plans were identified from July 1, 2012 to April 30, 2014 (N = 2,391), based on a published predictive model, and linked to 4,353 opioid-prescribing physicians. Patient-physician clusters were randomly assigned to one of four interventions using factorial design.