Silicon and Silver Low-Energy Ion Implantation into Titanium Plates for Improved Biocompatibility.

Surface modification of implant materials continues to address the issue of osseointegration. Moreover, combining osseointegration with bactericidal or antifouling properties in implants remains an open question for debate. Over the years, silver has been widely used as an agent for killing and preventing bacterial proliferation.

CLIA immunoassay as an alternative and accurate method to detect Sars-Cov-2 antigen compared to ELISA.

Background: COVID-19 has caused moderately severe infections in humans over the past few years, leading to >759 million confirmed cases. This situation highlights an urgent need to develop accurate diagnostic tests to monitor infectious disease and to adopt alternative methods such as CLIA to achieve low detection levels of proteins on diagnostic platforms.

Objectives: Develop in-house immunoassay for ELISA and CLIA to diagnose COVID-19.

Novel Coumarin-Nucleobase Hybrids with Potential Anticancer Activity: Synthesis, In Vitro Cell-Based Evaluation, and Molecular Docking.

A new series of compounds planned by molecular hybridization of the nucleobases uracil and thymine, or the xanthine theobromine, with coumarins, and linked through 1,2,3-triazole heterocycles were evaluated for their in vitro anticancer activity against the human tumor cell lines: colon carcinoma (HCT116), laryngeal tumor cells (Hep-2), and lung carcinoma cells (A549). The hybrid compound exhibited better activity in the series, showing an IC50 of 24.19 ± 1.

Desmarestia anceps Montagne modulates inflammatory response in experimental periodontitis in male Wistar rats.

Objective: Desmarestia anceps Montagne (D. anceps) seaweed has been shown to play a range of biologic activities, such as anti-inflammatory and antioxidant properties. The purpose of this study was to investigate the effects of D.

Comparative Study of Physicochemical Properties and Biocompatibility (L929 and MG63 Cells) of TiN Coatings Obtained by Plasma Nitriding and Thin Film Deposition.

Ti6Al4V is one of the most lightweight, mechanically resistant, and appropriate for biologically induced corrosion alloys. However, surface properties often must be tuned for fitting into biomedical applications, and therefore, surface modification is of paramount importance to carry on its use. This work compares the interaction between two different cell lines (L929 fibroblasts and osteoblast-like MG63) and medical grade Ti6Al4V after surface modification by plasma nitriding or thin film deposition.

Antimicrobial PAA/PAH Electrospun Fiber Containing Green Synthesized Zinc Oxide Nanoparticles for Wound Healing.

Wound infections are the main complication when treating skin wounds. This work reports a novel antimicrobial material using green synthesized zinc oxide nanoparticles (ZnONPs) incorporated in polymeric fibers for wound healing purposes. ZnONPs are a promising antimicrobial nanomaterial with high activity against a range of microorganisms, including drug-resistant bacteria.

Chemical Composition and Cytotoxic Evaluation of the Essential Oil of Phyllogonium viride (Phyllogoniaceae, Bryophyta).

The present study aimed to determine the chemical composition and biological activity of the essential oil obtained from Phyllogonium viride Brid. (Phyllogoniaceae, Bryophyta), whose samples were collected in southern Brazil. For the first time, the cytotoxic activity of the essential oil of P.