Protocol: Scoping review of the association between complementary feeding, growth, and immune health in infants and toddlers-An EAACI guideline paper.

The European Academy of Allergy and Clinical Immunology (EAACI) is currently developing guidelines on immunomodulation and nutrition. To inform these recommendations, a scoping review will be conducted to synthesize and map the available empirical evidence on how complementary feeding affects immune health in infants and toddlers to explore the association between complementary feeding during the first year of life and immune health outcomes in children up to 3 years of age. The scoping review will be conducted using the Preferred Reporting Items for Systematic Reviews and Meta-analysis Scoping Review Extension for scoping reviews (PRISMA-ScR) guidelines.

Recommendations for the use of biomarkers for the management of adults with sepsis: a scoping review and critical appraisal.

Objective: A synthesis and appraisal of the recommendations for biomarkers in practice guidelines concerning sepsis is required to consolidate evidence-based practice. We generated an evidence gap map (EGM) on the use of biomarkers for managing adults with sepsis.

Design: Scoping review.

Educational interventions and contextual factors for optimising antibiotic prescription in paediatric uncomplicated acute respiratory tract infections in primary care: scoping review of reviews.

Background: Inappropriate antibiotic prescription in paediatric uncomplicated acute respiratory tract infections (ARTIs) in primary care (PC) settings contributes to antimicrobial resistance. We aimed (1) to identify and describe educational interventions and their components to optimise antibiotic prescription for paediatric uncomplicated ARTIs in PC, and (2) to map contextual factors that may influence antibiotic prescription and the implementation of interventions.

Methods: We searched three electronic databases (Medline, CINAHL and Epistemonikos) to identify reviews on the effectiveness of educational interventions and contextual factors, for optimising antibiotic prescription (Concept) in paediatric uncomplicated ARTIs (Population) in PC (Context).

Users' experience of frameworks to support evidence-informed decision-making in public health: a scoping review.

BackgroundEvidence-informed decision-making in public health (PH) is a complex process requiring the consideration of multiple perspectives and contextual factors. Evidence-to-decision (EtD) frameworks are structured approaches aiming to improve decision-making by considering critical criteria, but users' experience has not been systematically synthesised.AimWe aim to summarise users' experiences of EtD frameworks used for PH.

Frameworks to support evidence-informed decision-making in public health and infectious disease prevention and control: a scoping review.

BackgroundEvidence-informed public health decision-making (EIDM) is a complex process that must consider multiple factors.AimWe aimed to identify and describe existing frameworks supporting evidence-informed public health decision-making and their application to infectious disease.MethodsWe conducted a scoping review to describe current EIDM framework use in public health.

Alignment between the research question, design, and terminology is required in manual therapy trials: a methodological study.

Objectives: The study aimed to assess the design, reporting, and risk of bias in effectiveness trials (ETs) in manual therapy (MT), comparing pragmatic with nonpragmatic trials and trials with and without placebo controls.

Study Design And Setting: We searched MEDLINE and the Cochrane Central Register of Controlled Trials for randomized controlled trials with the term "effectiveness" in the title or abstract in the field of MT from inception to January 2024. Two independent reviewers extracted data on specific study characteristics, their reporting, and risk of bias and assessed them using the PRagmatic Explanatory Continuum Indicatory Summary-2 tool (PRECIS-2).

Detection and treatment of early gestational diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials.

Objective: To estimate the impact of detection and treatment of early gestational diabetes mellitus on short-term maternal, fetal, and neonatal outcomes. We defined 2 maternal (gestational diabetes prevalence and cesarean section) and 2 neonatal (preterm birth and macrosomia) primary outcomes. We also defined 5 maternal and 12 fetal-neonatal secondary outcomes.

Evaluating physico-chemical and biological impacts of brine discharges for a sustainable desalination development on South America's Pacific coast.

The expansion of seawater desalination is presented as a new way to supply fresh water for many coastal regions as an effort to counteract the increasing water scarcity. However, brine discharges also pose significant environmental challenges regarding their potential environmental impacts of marine ecosystems. The main objective of this study was to assess the physico-chemical impact of the brine discharges from Seawater Reverse Osmosis (SWRO) desalination plants on South America pacific coastal ecosystems, assessing its potential physical-chemical impact (temperature, salinity, density and dissolved oxygen) on the receiving marine environment, and evaluating the oxidative and osmotic stress responses of the red macroalgae Rhodymenia corallina through diagnostic biomarkers in field-transplantation experiments.

Short-term exposure to desert dust and sandstorms and all-cause and cause-specific mortality and morbidity: A systematic review and meta-analysis.

Background: Desert dust and sandstorms raise concerns about their adverse effects on human health. Over the last decade, special attention has been given to mineral dust particles from desert sand. However, evidence from previous literature reviews has yielded inconclusive results regarding their health effects.

The evolutive role of shoot apical meristems in the adaptation of angiosperms to life at sea and the jump to potential environmental biotechnology applications.

Seagrasses have adapted to a submerged lifestyle in seawater through a complex set of evolutionary processes. However, they show sensitivity to increases in natural salinity levels such as those commonly found in discharges of desalination plants, which have exponentially grown due to water scarcity in highly populated temperate areas, such as the Mediterranean basin. This study assessed the effects of brine-derived hypersalinity on the Mediterranean seagrass Posidonia oceanica, focusing on the metabolic responses of shoot apical meristems (SAMs).

Scoping review of anticancer drug utilization in lung cancer patients at the end of life.

Purpose: This scoping review aims to deepen the understanding of end-of-life anticancer drug use in lung cancer patients, a disease marked by high mortality and symptom burden. Insight into unique end-of-life treatment patterns is crucial for improving the appropriateness of cancer care for these patients.

Methods: Comprehensive searches were carried out in Medline and Embase to find articles on the utilization of anticancer drugs in the end of life of lung cancer patients.

Assessment of brine discharges dispersion for sustainable management of SWRO plants on the South American Pacific coast.

Seawater desalination is one of the most feasible technologies for producing fresh water to address the water scarcity scenario worldwide. However, environmental concerns about the potential impact of brine discharge on marine ecosystems hinder or delay the development of desalination projects. In addition, scientific knowledge is lacking about the impact of brine discharges on the South America Pacific coast where desalination, is being developed.

Experience and satisfaction of participants in colorectal cancer screening programs: a qualitative evidence synthesis.

Background: Experience and satisfaction of colorectal cancer screening program participants are among the key factors that determine adherence to these programs. Understanding them is crucial to ensure future participation.

Objectives: To explore and gain understanding on the experience and satisfaction of the average-risk population participating in colorectal cancer screening programs.

The impact of indoor pollution on asthma-related outcomes: A systematic review for the EAACI guidelines on environmental science for allergic diseases and asthma.

Systematic review using GRADE of the impact of exposure to volatile organic compounds (VOCs), cleaning agents, mould/damp, pesticides on the risk of (i) new-onset asthma (incidence) and (ii) adverse asthma-related outcomes (impact). MEDLINE, EMBASE and Web of Science were searched for indoor pollutant exposure studies reporting on new-onset asthma and critical and important asthma-related outcomes. Ninety four studies were included: 11 for VOCs (7 for incidenceand 4 for impact), 25 for cleaning agents (7 for incidenceand 8 for impact), 48 for damp/mould (26 for incidence and 22 for impact) and 10 for pesticides (8 for incidence and 2 for impact).

The impact of outdoor pollution and extreme temperatures on asthma-related outcomes: A systematic review for the EAACI guidelines on environmental science for allergic diseases and asthma.

Air pollution is one of the biggest environmental threats for asthma. Its impact is augmented by climate change. To inform the recommendations of the EAACI Guidelines on the environmental science for allergic diseases and asthma, a systematic review (SR) evaluated the impact on asthma-related outcomes of short-term exposure to outdoor air pollutants (PM2.

Anticancer Drugs Compared to No Anticancer Drugs in Patients with Advanced Hepatobiliary Cancer: A Mapping Review and Evidence Gap Map.

Introduction: Despite being commonly recommended, the impact of anticancer drugs (ACDs) on patient-important outcomes beyond survival for advanced hepatobiliary cancers (HBCs) may not have been sufficiently assessed. We aim to identify and map the evidence regarding ACDs versus best supportive care (BSC) for advanced HBCs, considering patient-centered outcomes.

Methods: In this mapping review, we included systematic reviews, randomized controlled trials, quasi-experimental, and observational studies comparing ACDs (chemotherapy, immunotherapy, biological/targeted therapy) versus BSC for advanced HBCs.

Randomized controlled trials in nursing conducted by Latin American research teams: A scoping review.

Introduction: Randomized controlled trials (RCTs) are the cornerstone of systematic reviews and other evidence synthesis. RCT identification remains challenging because of limitations in their indexation in major databases and potential language bias. Scientific production in Latin American nursing is steadily increasing, but little is known about its design or main features.

Participants' satisfaction with colorectal cancer screening programs: A systematic review.

Introduction: Since satisfaction with cancer screening experience can increase adherence to programs and contribute to reduce morbidity and mortality, its assessment is crucial for programs´ effectiveness. Our aim was to conduct a systematic review about satisfaction of participants with organized colorectal cancer screening.

Methods: We searched relevant scientific databases (MEDLINE, EMBASE, PsycINFO, and CINAHL) from inception to May 2022.

Desalination brine effects beyond excess salinity: Unravelling specific stress signaling and tolerance responses in the seagrass Posidonia oceanica.

Desalination has been proposed as a global strategy for tackling freshwater shortage in the climate change era. However, there is a concern regarding the environmental effects of high salinity brines discharged from desalination plants on benthic communities. In this context, seagrasses such as the Mediterranean endemic and ecologically important Posidonia oceanica have shown high vulnerability to elevated salinities.

Search strategies (filters) to identify systematic reviews in MEDLINE and Embase.

Background: Bibliographic databases provide access to an international body of scientific literature in health and medical sciences. Systematic reviews are an important source of evidence for clinicians, researchers, consumers, and policymakers as they address a specific health-related question and use explicit methods to identify, appraise and synthesize evidence from which conclusions can be drawn and decisions made. Methodological search filters help database end-users search the literature effectively with different levels of sensitivity and specificity.

Perioperative glycaemic control for people with diabetes undergoing surgery.

Background: People with diabetes mellitus are at increased risk of postoperative complications. Data from randomised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control, targeting near-normal blood glucose, in people with hyperglycaemia (with and without diabetes mellitus) being submitted for surgical procedures. However, there is limited evidence concerning this question in people with diabetes mellitus undergoing surgery.

Risk-of-bias assessment of the randomized clinical trials and systematic reviews on surgical treatments for breast cancer-related lymphedema: A mapping review.

Background: Breast cancer treatment is the principal cause of lymphedema in the upper extremities. Breast cancer-related lymphedema (BCRL) treatments were previously based on conservative therapy; surgical treatments are alternative options that could be highly beneficial, especially for patients who are not responsive to conservative therapy. The main aim of this study was to describe and critically assess the risk of bias of randomized clinical trials (RCTs) and systematic reviews (SRs) on surgical treatment for BCRL.