Macular microvasculature asymmetry in high myopia patients with early open-angle glaucoma.

To evaluate the effectiveness of vertical asymmetry analysis of the macular microvasculature in high myopia patients with open-angle glaucoma (OAG). Participants were divided into two groups: those with high myopia (group 1) and those with both high myopia and OAG (group 2). Peripapillary retinal nerve fiber layer (RNFL) thickness, vessel density (VD), and the absolute vertical difference of RNFL thickness (vdRNFL) and VD (vdVD) were compared.

Effects of Topical Anti-Glaucoma Medications on Outcomes of Endoscopic Dacryocystorhinostomy: Comparison with Age- and Sex-Matched Controls.

Background: This study analyzed the effects of topical anti-glaucoma medications on the surgical outcomes of endoscopic dacryocystorhinostomy (EDCR) in nasolacrimal duct obstruction (NLDO).

Methods: This retrospective study included patients who underwent EDCR for NLDO between September 2012 and April 2021. Thirty patients with topical anti-glaucoma medications and 90 age- and sex-matched controls were included.

Analyses of the ratio of ganglion cell-inner plexiform layer thickness to vessel density according to age in healthy eyes.

Purpose: To identify how the inner retinal layer and microvasculature change with age by analyzing the relationships of ganglion cell-inner plexiform layer (GC-IPL) thickness, vessel density (VD), and the ratio of these measurements with age in healthy eyes.

Methods: Participants were divided into five groups according to age. The GC-IPL thickness, VD, and GC-IPL/VD ratio were compared among the groups.

Vertical asymmetry analysis of the macular microvasculature in epiretinal membrane patients with open-angle glaucoma.

To identify the usefulness of vertical asymmetry analysis of the retinal microvasculature in epiretinal membrane (ERM) patients accompanied by open-angle glaucoma (OAG). Subjects were divided into three groups: normal controls (group 1), patients with ERM (group 2), and patients with both ERM and OAG (group 3). Retinal nerve fiber layer (pRNFL) and ganglion cell-inner plexiform layer (GC-IPL) thicknesses, vessel density (VD), and the absolute vertical difference of pRNFL (vdRNFL), GC-IPL (vdGC-IPL), and VD (vdVD) were compared among groups.

Effect of Weiss ring on peripapillary retinal nerve fiber layer thickness measurements using SD-OCT.

Spectral-domain optical coherence tomography (SD-OCT) must accurately identify and measure the peripapillary retinal nerve fiber layer (pRNFL) thickness to improve the repeatability and reproducibility, and reduce measurement errors. Because Weiss ring can be located in front of the optic disc, we hypothesized that it may affect pRNFL thickness measurements obtained using SD-OCT. We retrospectively reviewed the medical records of patients with (group W) and without (group N) Weiss ring, observed on OCT fundus image and an RNFL map devised using SD-OCT.

The Ganglion Cell-Inner Plexiform Layer Thickness/Vessel Density of Superficial Vascular Plexus Ratio According to the Progression of Diabetic Retinopathy.

Purpose: The purpose of this study was to identify the relationship between the gangion cell-inner plexiform layer (GC-IPL) and retinal vasculature in the context of the progression of diabetic retinopathy (DR).

Methods: The subjects were divided into four groups according to DR stage: normal controls (group 1), patients with diabetes mellitus (DM) without DR (group 2), patients with mild or moderate nonprogressive DR (NPDR; group 3), and patients with severe NPDR (group 4). GC-IPL thickness, vessel density of superficial vascular plexus (SVD), and the GC-IPL/SVD ratio were compared among the groups.

Twenty-seven-gauge endoilluminator-assisted scleral buckling using a wide-field viewing system: Case report.

Rationale: We report a new scleral buckling technique using a 27-gauge endoilluminator and a wide-field viewing system to overcome the limitations of conventional indirect ophthalmoscope-methods and "chandelier-assisted" surgery.

Patient Concerns: A 26-year-old female patient visited the local clinic for floaters and lower visual field defects in her left eye that had occurred 5 days prior.

Diagnoses: On fundus examination, upper retinal detachment without macular involvement and an atrophic hole was observed in her left eye.

Effect of axial length on peripapillary microvasculature: An optical coherence tomography angiography study.

Objective: To investigate the effects of axial length (AL) on the peripapillary microvascular density acquired from optical coherence tomography angiography (OCTA).

Methods: Retrospective observational study. A total of 111 eyes from 111 normal healthy subjects were examined.

Wide-Field Swept-Source OCT Analysis of Interocular Symmetry of Choroidal Thickness in Subjects with Uncomplicated Pachychoroid.

Background: We aimed to study the bilateral choroidal thickness (CT) symmetry and difference in uncomplicated pachychoroid subjects using wide-field swept-source optical coherence tomography (SS-OCT).

Methods: All subjects underwent a wide-field 16-mm one-line scan using SS-OCT. Bilateral CT was measured at, and compared among, the following 12 points: three points at 900-µm intervals from the nasal optic disc margin (nasal peripapillary area), one point at the subfovea, six points at 900-µm intervals from the fovea to the nasal and temporal areas (macular area), and two peripheral points 5400 and 8100 µm from the fovea (peripheral area).

Effect of Systemic Hypertension on Peripapillary RNFL Thickness in Patients With Diabetes Without Diabetic Retinopathy.

Type 2 diabetes mellitus (T2DM) and hypertension (HTN) are both relatively common systemic diseases and cause damage to the retina, such as inner retina reduction and microvascular impairment. The purpose of this study was to identify peripapillary retinal nerve fiber layer (pRNFL) damage by diabetic neurodegeneration and the effects of HTN on the pRNFL thickness in patients with T2DM without clinical diabetic retinopathy. Subjects were divided into three groups: healthy control subjects (group 1), patients with T2DM (group 2), and patients with both diabetes and HTN (group 3).

Association of high myopia with peripapillary retinal nerve fiber layer in patients with hypertension.

Purpose: To identify the impacts of hypertension (HTN), high myopia, and the combination thereof on peripapillary retinal nerve fiber layer (pRNFL) thickness.

Methods: All subjects were divided into four groups: control (group 1); patients with HTN without high myopia (group 2); patients with high myopia without HTN (group 3); and patients with both HTN and high myopia (group 4). The pRNFL thicknesses were compared using a one-way analysis of variance.

Risk Factors for Orbital Implant Extrusion after Evisceration.

Unlabelled: This study analyzed risk factors for extrusion of orbital implants after evisceration by comparing patients with and without implant extrusion.

Methods: We retrospectively reviewed the medical records of patients who underwent evisceration with primary implant placement by a single surgeon from January 2005 to December 2019 at the Chungnam National University Hospital. Age, sex, underlying systemic diseases, axial length of the fellow eye, the cause of evisceration, endophthalmitis type, implant type and size, and preoperative computed tomography findings were evaluated.

Effects of Beta-zone Peripapillary Atrophy and Focal Lamina Cribrosa Defects on Peripapillary Vessel Parameters in Young Myopic Eyes.

Precis: The development of beta-zone peripapillary atrophy (β-PPA) and focal lamina cribrosa defect (FLD) was significantly associated with decreased peripapillary optical coherence tomography angiography (OCTA) vessel parameters in young myopic eyes.

Purpose: The purpose of this study was to investigate whether β-PPA and FLD affect peripapillary vessel density (VD) or perfusion density (PD) from OCTA in young myopic eyes.

Materials And Methods: In a cross-sectional study, 330 eyes of 165 healthy volunteers with myopia were involved.

Retinal nerve fibre layer/ganglion cell-inner plexiform layer thickness ratio in patients with systemic hypertension.

Purpose: Acute and chronic hypertension may have different pathophysiological mechanisms in the retina. Here, we compared the retinal nerve fibre layer (RNFL)/ganglion cell-inner plexiform layer (GC-IPL) thickness ratios of patients with 'relieved' severe hypertensive retinopathy (relieved HTNR) and chronic hypertension without retinopathy (chronic HTN) to those of normal controls.

Methods: We performed cross-sectional study.

REPEATABILITY OF MACULAR MICROVASCULATURE MEASUREMENTS USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY ACCORDING TO TEAR BREAKUP TIME IN DRY EYE DISEASE.

Purpose: It is hypothesized that an unstable tear film would affect the quality and repeatability of optical coherence tomography angiography (OCTA). Therefore, OCTA repeatability according to tear break-up time (TBUT) was compared.

Methods: The 3 × 3 OCTA was performed twice and, the eyes were divided into 3 groups according to the TBUT (Group 1: TBUT ≤ 5 seconds, 43 eyes; Group 2: 5 seconds < TBUT ≤ 10 seconds, 35 eyes; Group 3: TBUT > 10 seconds, 34 eyes).

Wide-Field Swept-Source Optical Coherence Tomography Analysis of Interocular Symmetry of Choroidal Thickness in Healthy Young Individuals.

Purpose: The purpose of this paper was to study the bilateral choroidal thickness (CT) symmetry and differences in healthy individuals using wide-field swept-source optical coherence tomography (SS-OCT).

Methods: All participants underwent a wide-field 16-mm 1-line scan using SS-OCT. CTs were measured at the following 12 points: 3 points at 900 µm, 1800 µm, and 2700 µm away from the nasal optic disc margin (nasal peripapillary area), 1 point at the subfovea, 6 points at 900 µm, 1800 µm, and 2700 µm away from the subfovea to the nasal and temporal areas (macular area), and 2 peripheral points at 2700 and 5400 µm from temporal point 3 (peripheral area).

Longitudinal changes in the ganglion cell-inner plexiform layer thickness of age-related macular degeneration.

Purpose: To determine longitudinal changes of the ganglion cell-inner plexiform layer (GC-IPL) thickness in patients with non-exudative age-related macular degeneration (AMD) without other ophthalmic disease.

Methods: Thirty-three eyes of 33 patients with early and intermediate non-exudative AMD (non-exudative AMD group) and 33 normal control eyes were followed for 2 years, and GC-IPL thickness was measured by spectral domain optical coherence tomography at 1-year intervals. The mean rate of GC-IPL reduction was estimated using a linear mixed model and compared between two groups.

The effect of initial intravitreal tissue plasminogen activator and gas injection on vision improvement in patients with submacular haemorrhage associated with age-related macular degeneration.

Purpose: To compare visual improvements between initial intravitreal t-PA with gas injection before anti-vascular endothelial growth factor (VEGF) and anti-VEGF injection monotherapy for submacular haemorrhage (SMH) associated with age-related macular degeneration (AMD).

Methods: We retrospectively reviewed medical records of naive patients treated with intravitreal t-PA with gas injection before anti-VEGF (Group 1) or only with intravitreal anti-VEGF injection (Group 2) for SMH [disc area (DA) ≥ 2] associated with AMD from two institutions. Both groups received 3 monthly loads of anti-VEGF injections followed by injections as needed for AMD treatment.

Characteristics of the inner retinal layer in the fellow eyes of patients with unilateral exudative age-related macular degeneration.

Objective: To investigate the thicknesses of the ganglion cell-inner plexiform layer (GC-IPL) and retinal nerve fiber layer (RNFL) of the fellow eyes of patients with unilateral exudative age-related macular degeneration (AMD).

Methods: A total of 107 patients with unilateral exudative AMD [34 of typical choroidal neovascularization (tCNV), Group A; 73 of polypoidal choroidal vasculopathy (PCV), Group B] and 73 normal control eyes (Group C) were included. Drusen and subretinal drusenoid deposits were assessed in all participants using fundus photography, autofluorescence, and optical coherence tomography (OCT).

Association of Myopia with Peripapillary Retinal Nerve Fiber Layer Thickness in Diabetic Patients Without Diabetic Retinopathy.

Purpose: To investigate the association between myopia and peripapillary retinal nerve fiber layer (pRNFL) thickness in diabetic patients without diabetic retinopathy (DR).

Methods: A total of 271 eyes of 271 participants were included. They were divided into four groups according to the presence of myopia (≤ -3 diopters [D]) and diabetes without DR: (1) control group (n = 76), (2) myopia group (n = 57), (3) diabetes group (n = 82), and (4) diabetes + myopia group (n = 56).

Peripapillary vessel parameters and mean ocular perfusion pressure in young healthy eyes: OCT angiography study.

Background: To investigate the relationship between estimated mean ocular perfusion pressure (MOPP) and peripapillary perfusion density (PD) or vessel density (VD) as measured by spectral-domain optical coherence tomography angiography (OCTA) in young healthy eyes.

Methods: 132 healthy participants (264 eyes) under 45 years of age underwent optic disc OCTA scan sized 3×3 mm to acquire PD and VD in the superficial vascular complex (SVC). Optic nerve head (ONH) parameters including retinal nerve fibre layer (RNFL) thickness, rim area and disc area were measured.

Clinical characteristics and prognosis of Total Rhegmatogenous retinal detachment: a matched case-control study.

Background: Although many studies have reported clinical features, surgical outcomes of rhegmatogenous retinal detachment (RRD), studies focusing on total RRD are rare. In this study, we investigate the clinical characteristics, risk factors, and prognosis of total RRD.

Methods: A retrospective chart review was performed on cases of 44 total RRD and an age- and sex-matched 88 partial RRD.

Repeatability of measuring the vessel density in patients with retinal vein occlusion: An optical coherence tomography angiography study.

Purpose: To determine the repeatability of superficial vessel density measurements using Spectral domain Ocular coherence tomography angiography(SD-OCTA) in patients diagnosed with retinal vein occlusion(RVO).

Design: Prospective observational study.

Subjects: Patients who visited our retinal clinic from August 2017 to August 2018, diagnosed with RVO were recruited for the study.

A comparison of choroidal thicknesses between pachychoroid and normochoroid eyes acquired from wide-field swept-source OCT.

Purpose: We investigated the wide-field choroidal thickness (CT) using swept-source optical coherence tomography (SS-OCT) and compared the characteristics of the choroidal layer between pachychoroid and normochoroid groups.

Methods: A total of 120 eyes from 120 normal subjects were included. All subjects were divided into two groups according to the subfoveal CT (≥300 μm, pachychoroid group; <300μm, normochoroid group).