Publications by authors named "Hyangsook Lee"

This study analyzes the anticipated impact of the deployment of green ships on reducing air pollutant emissions. We estimated air pollutant emissions from ships in Incheon Port, South Korea, and conducted a literature review and expert interviews to analyze changes in emissions as a function of the rate at which new ships can be converted to green ships in the future. The analysis showed that the PM10 and PM2.

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Article Synopsis
  • Traditional medicine (TM) is important in healthcare and this study aimed to analyze systematic reviews (SRs) of TM modalities to identify gaps in existing research and inform future studies.
  • The researchers conducted a comprehensive search across 17 databases from January 2018 to December 2022, ultimately screening over 181,000 records to include 2,719 relevant SRs focusing mainly on adults and specific health conditions.
  • The study found that most TM research concentrated on herbal medicine and acupuncture for conditions related to the digestive, circulatory, and genitourinary systems, while highlighting low methodological quality of the included SRs as a concern for future TM research efforts.
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Background: This study aimed to investigate whether placebo control is differently disclosed in drug and non-drug randomised clinical trial (RCT) participant information leaflets (PILs) and how this might affect participant blinding and direction of study outcomes.

Methods: PILs were obtained from trials registered in the International Standard Randomised Controlled Trial Number database via email. Placebo descriptions in PILs were categorised as Full Disclosure (FD), Partial Disclosure (PD), or Missing Information (MI).

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Acquisition of defect-free transition metal dichalcogenides (TMDs) channels with clean heterojunctions is a critical issue in the production of TMD-based functional electronic devices. Conventional approaches have transferred TMD onto a target substrate, and then apply the typical device fabrication processes. Unfortunately, those processes cause physical and chemical defects in the TMD channels.

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  • The B7-H3 protein, linked to poor clinical outcomes in various cancers, is a target for new cancer treatments due to its high expression in tumors and limited presence in normal tissues.
  • The study introduces ITC-6102RO, an innovative antibody-drug conjugate designed to selectively deliver a cytotoxic agent to B7-H3-overexpressing cancer cells, demonstrating effectiveness in both cell lines and xenograft models.
  • Results showed that ITC-6102RO reduces cell viability by inducing cell cycle arrest, DNA damage, and apoptosis in cancer cells, indicating its potential as a therapeutic option for B7-H3-targeted therapy.
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This paper presents the Acupuncture Controls gUideline for Reporting humAn Trials and Experiments (ACURATE) checklist, an extension of The Consolidated Standards for Reporting of Trials (CONSORT), which is to be used with STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) when real and sham acupuncture needles are used in a study. This checklist focuses on a clear depiction of sham needling procedures to enhance replicability and enable a precise appraisal. We encourage researchers to use ACURATE in trials and reviews involving sham acupuncture to assist in the reporting of sham acupuncture procedures and related components.

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Objective: The optimal treatment for facet joint cysts (FJCs) has remained controversial. Despite a higher success rate than the conservative option, surgical treatments may pose risks of postoperative complications and comorbidities may make the surgical approach difficult. Thus, this study reports four cases of pain amelioration and resorption of FJCs through noninvasive integrative Korean Medicine treatment.

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Article Synopsis
  • The paper introduces the ACURATE checklist, designed to improve reporting standards for human trials involving acupuncture, particularly when comparing real and sham needles.
  • It builds upon existing guidelines like CONSORT and STRICTA, emphasizing the need for clear descriptions of sham acupuncture practices for better reproducibility.
  • The authors advocate for the use of ACURATE in research to enhance the quality of reporting on sham acupuncture trials and their associated methods.
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Background: Obesity is a public health issue worldwide. Conversational agents (CAs), also frequently called chatbots, are computer programs that simulate dialogue between people. Owing to better accessibility, cost-effectiveness, personalization, and compassionate patient-centered treatments, CAs are expected to have the potential to provide sustainable lifestyle counseling for weight management.

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Objective: To promote better reporting quality regarding sham acupuncture in clinical trials for a precise appraisal of the adequacy of the sham acupuncture procedure.

Methods: A three-stage online Delphi survey was conducted to a group of experts. Items with higher than 80% consensus from the initial checklist were selected as the final candidates.

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Sham acupuncture should have two distinct features: first, it must be morphologically similar to verum acupuncture for blinding purposes, and second, it must not exert physiologically expected effects of verum acupuncture. While several types of sham acupuncture are currently used, there are on-going debates on which sham acupuncture can meet the criteria for being an appropriate control intervention in acupuncture research. In view of this situation, it is unreasonable to regard the use of sham acupuncture in acupuncture research as the same as the use of placebo drugs in drug research.

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Background: To evaluate safety of acupuncture treatment by Korean Medicine Doctors (KMDs), a prospective, practice-based survey on adverse events (AEs) associated with acupuncture was conducted.

Methods: From July 2016 to October 2017, KMDs were invited to participate in an online survey. Frequency was calculated as the number of AEs per 10,000 treatments; severity was assessed with the Common Terminology Criteria for Adverse Events Grading (Severity) Scale; and causality was evaluated using the World Health Organisation-Uppsala Monitoring Centre system for standardised case causality assessment.

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Background: This study aimed to explore individual prevalence of respiratory symptoms and to describe the Korean population's treatment approaches, preventive health behaviors, and mental health conditions during the pandemic.

Methods: We analyzed responses from an online nationwide survey, conducted between February 2021 to May 2021, about people's experiences during the pandemic. Statistical analysis was also performed to see if there were any significant differences in treatment and prevention strategies between different groups of respondents (between those had respiratory symptoms, compared with those who did not, and between those tested positive for COVID-19, compared with those who did not).

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Objective: Acupotomy is a modern acupuncture method that includes modern surgical methods. Since acupotomy is relatively more invasive than filiform acupuncture treatment, it is important to establish the safety profile of this practice. To justify further large-scale prospective observational studies, this preliminary study was performed to assess the feasibility of the approach and investigate the safety profile and factors potentially associated with adverse events (AEs).

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Objective: The description of controls is important in acupuncture clinical trials to interpret its effectiveness without fallacy. This paper aims to evaluate the reporting quality of acupuncture studies on the characteristics of sham needles.

Study Design And Setting: Using a checklist developed from previously published reporting guidelines, the distribution of reported items and changes of reporting rates over time were investigated.

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By controlling the configuration of polymorphic phases in high-k Hf Zr O thin films, new functionalities such as persistent ferroelectricity at an extremely small scale can be exploited. To bolster the technological progress and fundamental understanding of phase stabilization (or transition) and switching behavior in the research area, efficient and reliable mapping of the crystal symmetry encompassing the whole scale of thin films is an urgent requisite. Atomic-scale observation with electron microscopy can provide decisive information for discriminating structures with similar symmetries.

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This randomized clinical trial investigates the effect of partial vs full disclosure of potential assignment to placebo on participant blinding, perceptions of group assignment, and clinical outcomes.

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Background Bone fractures are important clinical events for both patients and professionals. Active treatment options are limited for delayed unions and for nonunions; surgery is common but not entirely risk-free. This report describes three cases of delayed union successfully treated with herbal decoction.

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2D multiferroics with combined ferroic orders have gained attention owing to their novel functionality and underlying science. Intrinsic ferroelastic-ferroelectric multiferroicity in single-crystalline van der Waals rhenium dichalcogenides, whose symmetries are broken by the Peierls distortion and layer-stacking order, is demonstrated. Ferroelastic switching of the domain orientation and accompanying anisotropic properties is achieved with 1% uniaxial strain using the polymer encapsulation method.

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Fracture healing is related to osteogenic differentiation and mineralization. Recently, due to the unwanted side effects and clinical limitations of existing treatments, various natural product-based chemical studies have been actively conducted. Albiflorin is a major ingredient in , and this study investigated its ability to promote osteogenic differentiation and fracture healing.

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Article Synopsis
  • * The study reveals that these enhanced properties come from unique microstructure and crystallographic orientations in ultrathin HZO films, specifically with a preferred orientation of (112) that increases net polarization by 62% compared to thicker, randomly oriented samples.
  • * Researchers used advanced analysis techniques to study these films and found that hydroxyl adsorption during deposition lowers surface energy, helping to stabilize the beneficial (112)-oriented grains, offering new strategies for designing future compact electronic devices.
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