Vector Control, Pest Management, Resistance, RepellentsEvaluation of fruit sjuice preferences by Aedes, Anopheles, and Culex mosquito (Diptera: Culicidae) species for the development of effective attractive toxic sugar baits.

Mosquito-borne diseases pose significant public health challenges, necessitating the development of effective and sustainable vector control strategies. This study investigated the feeding preferences of 4 mosquito species (Aedes aegypti Linnaeus, Aedes albopictus Skuse, Culex quinquefasciatus Say, and Anopheles quadrimaculatus Say) for various fruit juices using a home-made choice chamber. We also assessed the impact of combining biogents lure and boric acid into attractive toxic sugar baits to enhance mosquito attraction and mortality.

Effect of working length determination methods on postoperative pain after root canal treatment: a systematic review and meta-analysis.

This systematic review aimed to assess the effect of various working length determination methods on the incidence of postoperative pain after root canal treatment. A comprehensive literature search was conducted across three electronic databases to identify randomized clinical trials. Two reviewers independently screened the articles, extracted relevant data, and assessed methodological quality using the Cochrane risk-of-bias assessment tool.

Multi-scale simulations of MUT-16 scaffold protein phase separation and client recognition.

Phase separation of proteins plays a critical role in cellular organization. How phase-separated protein condensates underpin biological function and how condensates achieve specificity remain elusive. We investigated the phase separation of MUT-16, a scaffold protein in Mutator foci, and its role in recruiting the client protein MUT-8, a key component in RNA silencing in Caenorhabditis elegans.

Perceived Barriers, Facilitators, and Needs Related to Promoting Physical Activity in Cancer Care: Qualitative Insights from Oncology Care Providers.

Physical activity (PA) is associated with lower mortality and cancer recurrence risks. Although evidence shows health benefits for cancer patients before, during, and immediately after treatment, PA recommendations are not regularly included in the standard care. The study aimed to identify perceived knowledge, barriers, and facilitators of oncology providers' PA promotion for cancer patients using the 5A (Assess, Advise, Agree, Assist, and Arrange) framework.

Amine functionalized quinolinium polyoxometalates as highly active heterogeneous catalysts for solvent-free CO cycloaddition and Knoevenagel condensation reactions.

Introducing task-specific catalytic sites through rational design is paramount while developing a multifunctional catalyst for organic transformation reactions. In this work, we utilized rarely explored quinolinium counterions to build a new class of quinolinium-polyoxometalate (POM) hybrids and test their catalytic activities in various organic transformation reactions. We introduced a task-specific '-NH' functional group onto the quinolinium moiety to enhance basic and hydrogen bonding sites towards the catalytic reactions and developed a series of POM-hybrids (ACMQ)[HVO] (hybrid 1), (ACMQ)[SiMoO] (hybrid 2) and (ACMQ)[SiWO] (hybrid 3) (where ACMQ = 4-amino-7-chloro-1-methylquinolin-1-ium) starting from common POM precursors.

Hybrid deep-CNN and Bi-LSTM model with attention mechanism for enhanced ECG-based heart disease diagnosis.

According to the World Health Organization (WHO), 17.9 million people die yearly from cardiovascular Diseases (CVDs), including heart attacks. Cardiovascular diseases, including heart attack, kill 32% of people globally.

Effectiveness of introducing pulse oximetry and clinical decision support algorithms for the management of sick children in primary care in India and Tanzania on hospitalisation and mortality: the TIMCI pragmatic cluster randomised controlled trial.

Background: Pulse oximetry can support better detection of hypoxaemia, an important mortality predictor, and digital clinical decision support algorithms (CDSAs) can strengthen adherence to Integrated Management of Childhood Illness (IMCI) guidelines. This study sought to address evidence gaps on the impact of providing these tools to primary care healthcare providers on under-five hospitalisations and mortality.

Methods: A pragmatic, parallel group, superiority, cluster randomised controlled trial (RCT) conducted in 172 primary care facilities in India and Tanzania (106 and 66 facilities, respectively).

A review of biofuels and bioenergy production as a sustainable alternative: opportunities, challenges and future perspectives.

Biofuels and bioenergy production are increasingly being viewed as viable alternatives to conventional energy sources because of their renewable nature and ability to reduce greenhouse gas emissions. Waste products, lignocellulosic materials, and agricultural residues are some of the feedstocks that can be used to create biofuels, including biodiesel, bioethanol, and biogas. The production of biofuels not only promotes sustainable energy but also addresses environmental problems.

Driving diverse bond functionalisation with -heterocyclic silylene-coinage metal-aryl complexes.

Anchoring homolytic and heterolytic bond functionalisation at low-coordinate coinage metal centres is important due to their potential use as active catalysts in organic transformations. In the realm of carbene-stabilised coinage metal chemistry, heteroatom functionalised coinage metal precursors synthesised from such bond activations have long been explored. Interestingly, -heterocyclic silylene, being an equally potent neutral donor ligand, has not been used for the same.

Nanoparticle-based detection of foodborne pathogens: Addressing matrix challenges, advances, and future perspectives in food safety.

Foodborne diseases pose significant public health and economic challenges worldwide, with conventional pathogen detection methods, such as culture-based assays and PCR, often hindered by the complex food matrix in categories like dairy, seafood, fresh produce, and processed foods. These matrices, containing fats, proteins, biofilms, and salts, interfere with detection accuracy, reducing the sensitivity and robustness of traditional approaches. Nanoparticle-based detection systems have emerged as transformative tools to overcome these challenges, offering enhanced sensitivity, rapid detection, and adaptability to real-time monitoring.

Prevalence of Radix Entomolaris in Patients at a Multidisciplinary Tertiary Care Hospital of Jharkhand, India.

Aim: To investigate the incidence of radix entomolaris in mandibular molars in patients reporting to a tertiary care center in Jharkhand.

Materials And Methods: 2640 mandibular molars were assessed using intraoral periapical digital radiography where the total incidence of radix entomolaris and the ratio of their occurrence among gender and location were evaluated.

Results: The overall incidence of radix entomolaris was found to be 2.

Description of Stieleria mannarensis sp. nov., isolated from a marine sponge, and proposal to include members of the genus Roseiconus in the genus Stieleria.

A pink-coloured, salt- and alkali-tolerant strain, JC639, was isolated from a specimen of the marine sponge Spheciospongia sp. The novel isolate is motile, aerobic and forms oval to pear-shaped cells. It shares the highest 16S rRNA gene sequence identity with Stieleria neptunia Enr13 and Stieleria maiorica Mal15 in the family Pirellulaceae (phylum Planctomycetota).

Zinc-solubilizing bacterial consortia: a promising approach for zinc biofortification of crops.

The term "zinc-solubilizing bacteria" (ZSB) refers to a specific group of soil bacteria that are associated with zinc-solubilizing activity in the soil through a variety of mechanisms. The functional use of ZSB has been proposed for the zinc (Zn) biofortification of crops to address Zn malnutrition. The application of zinc-solubilizing bacterial inoculants that harbor significant plant probiotic traits offers an eco-friendly approach to producing crops with improved Zn content in various edible parts of plants.

Cullin-3 regulates the renal baroreceptor machinery that controls renin gene expression.

Mutations in Cullin-3 (CUL3) cause hypertension (HTN). We examined the role of smooth muscle cell (SMC) CUL3 in the regulation of renin gene expression. Mice with SMC-specific CUL3 deletion (S-CUL3-KO) developed severe HTN with paradoxically preserved levels of plasma angiotensin peptides and renal renin expression.

Discovery of effectors for casein kinase signaling in the African trypanosome.

Extensive divergence of protein sequences from those of model eukaryotes makes recognition of well-studied signaling pathways impossible in Trypanosoma brucei. Consequently, substrates and effectors of most protein kinases are unknown. We addressed these general problems by developing workflows to (i) identify effectors for protein kinases, (ii) discover new effectors and substrates of CK1.

Ligand-Receptor Analysis of Brain Cell Type Marker Data Reveals Intricate Endothelial Interaction.

Background: Brain endothelial interaction with neurons, astrocytes, oligodendrocytes and microglial cells is critical for brain physiology; it is still far from being mapped. Understanding of the endothelial communication with other brain cell type could unravel novel insight into neurovascular homeostasis.

Purpose: This study aims to construct neurovascular interaction network, focusing on brain endothelial cell interactome using brain cell marker gene dataset and ligand-receptor (LR) pair.

Study on the Preoperative and Postoperative Levels of Serum Lactate to Estimate Morbidity and Mortality in Cases of Bowel Perforation at a Tertiary Care Hospital in Jharkhand, India.

Introduction Bowel perforation is a common emergency with high morbidity and mortality. The patient presented with acute abdomen, abdominal distention, obstipation, and frequent gas under the diaphragm on radiogram. Arterial blood gas (ABG) is one of the earliest investigations done in cases of suspected bowel perforation in the Emergency Room (ER), and includes serum lactate.

Climatic and ecological factors responsible for distribution of Phlebotomine sandflies and occurrence of cutaneous leishmaniasis, in Himachal Pradesh, India.

Background Objectives: Subalpine valley along the Sutlej River has been identified as an endemic focus for cutaneous leishmaniasis (CL) in Himachal Pradesh (H.P.) state in India.

Microplastic contamination in fish: A systematic global review of trends, health risks, and implications for consumer safety.

Microplastic contamination in fish presents a growing environmental and public health concern, with implications that extend from aquatic ecosystems to consumer safety. This review presents a systematic summary of current knowledge about the health hazards of microplastics in fishes, including bioaccumulation, transfer mechanisms in the food chain, and the roles of microplastics as carriers of antibiotic-resistant genes. By comparing the level of contamination in both safely grown mud fish under aquaculture and directly from natural sources such as nearby coastal areas, we are able to point out the fluctuations of the risks of being contaminated from the different sources for a common consumer and suitable bodies to take action on which type of seafood should be preferred.

Effect of Salinity on Mosquito ( Aedes ) Oviposition Preference and Survival of Larvae: A Laboratory-based Study.

Background: Vector control measures assume utmost importance in the absence of specific treatment against clinically complicated Dengue virus infections. Preventive measures such as reduction of mosquito larvae breeding hot spots also include spraying of insecticides. However, insecticides pose a risk to the general population as well as to the environment.

Role of the Renin-Angiotensin System in Blood Pressure Regulation in Smooth Muscle-Specific Cullin-3 Deficient Mice.

Background: Selective ablation of CUL3 (Cullin-3) in vascular smooth muscle cell-selective CUL3 knockout (S-CUL3KO) results in severe hypertension with paradoxically unaltered ANG II (angiotensin II) levels, suggesting an increase in ANG II sensitivity. We hypothesized that the hypertension and vascular dysfunction in S-CUL3KO mice are mediated by an exaggerated calcium response to ANG II in vascular smooth muscle cells.

Methods: Blood pressure was measured by radiotelemetry in S-CUL3KO mice subjected to pharmacological inhibition of the renin-angiotensin system.

Biomimetic Computing for Efficient Spoken Language Identification.

Spoken Language Identification (SLID)-based applications have become increasingly important in everyday life, driven by advancements in artificial intelligence and machine learning. Multilingual countries utilize the SLID method to facilitate speech detection. This is accomplished by determining the language of the spoken parts using language recognizers.

Photoinduced Direct Formylation of Anilines: Aerobic Oxidation Using an Odd Alternate Hydrocarbon Phenalenyl-Based Photocatalyst.

We have introduced a sustainable approach for the photoinduced oxidative formylation of -dimethylanilines using a phenalenyl-based photocatalyst. The methodology exhibits tolerance to a variety of electron-donating and -withdrawing groups as well as to diverse functional groups, specifically offering a selective and efficient pathway for the -formylation. Using visible light, this photochemical technique proves to be an environmentally friendly, scalable, and milder alternative strategy.

Ultrasound-assisted hydration offers a novel approach to anneal in-situ pinto bean starch.

Ultrasound is considered an emerging technology capable of altering macromolecular structures linked to functionality. However, its effects vary depending on whether the ultrasound processing is applied with or without temperature control. This variability creates ambiguity regarding the effects of ultrasound on macromolecules such as starch, which is abundant in cereals and legumes.