Purpose: This study aimed to compare the accuracy of orthodontic tooth movements achieved with three-dimensionally (3D) printed aligners (Noxi, Sweden&Martina, Due Carrare, Padova, Italy) using a 12 h/day protocol with that of thermoformed aligners (F22 aligner, Sweden&Martina, Due Carrare, Padova, Italy) using a 22 h/day protocol.
Methods: Of the 40 white adult patients (12 men and 28 women, mean age 30.1 years) undergoing orthodontic treatment with aligners selected based on specific inclusion criteria, 20 patients were treated with Noxi aligners using a 12 h/day protocol (study group), and the remaining 20 patients were treated with F22 aligners using a 22 h/day protocol (control group).
Comput Biol Med
June 2025
Background: Cephalometric analysis in orthodontics is a meticulous process requiring high precision in identifying anatomical landmarks on lateral cephalometric radiographs. Manual analysis by clinicians remains the standard, as even slight deviations in landmark placement can lead to incorrect diagnoses. Despite advancements in AI, automatically localizing these landmarks remains challenging, with few systems meeting the exacting standards of European orthodontic practice.
View Article and Find Full Text PDF: Long-COVID is characterized by the persistency of COVID-19 symptoms beyond 12 weeks, and it is probably consequent to immune dysregulation induced by SARS-CoV-2 infection. Immune dysregulation is associated with and probably involved in the pathogenesis of chronic gynecological conditions like endometriosis and adenomyosis. This study evaluated whether the presence of endometriosis or adenomyosis increases the risk of long-COVID, i.
View Article and Find Full Text PDFIntroduction: To compare the in-vitro accuracy of guided palatal miniscrew insertion comparing expert and inexpert clinicians.
Material And Methods: Twenty-one synthetic bone models, derived from a single master model, were acquired to simulate the clinical act of miniscrew insertion. Digital planning and CAD/CAM surgical guide manufacturing were executed by matching the CBCT of the master model with its corresponding STL file.
The aim of this study was to describe the successful treatment of an anterior open bite in an adult Class II hyperdivergent patient. A 31-year-old female presented for orthodontic treatment, seeking an aesthetic solution to correct her anterior open bite and lower crowding to enhance her smile. As an initial step, all third molars were extracted to facilitate the forward rotation of the mandible and the initial closure of the open bite.
View Article and Find Full Text PDFThis case report describes the successful non-extraction orthodontic treatment of a 13-year-old female patient affected by a Class II Division 2 malocclusion, maxillary constriction and a unilateral impacted maxillary canine. The miniscrew-assisted palatal expansion (MAPA) system was used for precise palatal miniscrew placement, achieving bicortical engagement. A hybrid T-Rex rapid palatal expander was then employed to achieve both skeletal expansion and molar distalization without requiring patient compliance.
View Article and Find Full Text PDFBackground: Alzheimer's disease is a slowly progressing neurodegenerative illness and the most common form of dementia. This pathology leads to an increase in cognitive decline and is responsible, in patients, for several difficulties in performing various activities of daily living, such as oral hygiene. Several experimental studies have shown that oral health in patients with Alzheimer's disease worsens in direct proportion to the progression of the disease due to the appearance of gingivitis and periodontitis.
View Article and Find Full Text PDFAm J Orthod Dentofacial Orthop
February 2025
Introduction: The aim was to compare the soft tissue changes in pretreatment and posttreatment facial scans of patients who had undergone various orthopedic treatments vs a control group of untreated growing patients.
Methods: Facial scans were performed before (T0) and after (T1) orthopedic treatment in 15 patients prescribed rapid palatal expander (RPE), 15 cervical headgear (HG), and 15 facemasks (FM), as well as 6 months apart in 15 untreated growing patients. After best-fit scan alignment using Geometric Control X software (3D Systems Inc, Rock Hill, SC), a 3-dimensional (3D) analysis of soft tissue changes was performed, comparing 3D reference points (total 22) and 8 areas on T0 and T1 scans.
: Periodontal disease is an inflammatory, chronic, and multifactorial disease. The objective of this study is to analyze the association between periodontal disease and some disorders such as papillomas (benign lesions), lichen planus (a chronic immune-mediated disorder), leukoplakia (potentially malignant lesions), and oral cancer (malignant lesions). : For this study, 42 patients were recruited whose supragingival and subgingival plaque was qualitatively analyzed using a phase-contrast microscope, which allowed for the detection of compatible bacterial flora (immobile and composed mainly of cocci) indicative of periodontal health and incompatible bacterial flora (mobile and composed mainly of spirochetes) indicative of periodontal pathology.
View Article and Find Full Text PDFThe aim was to objectively assess compliance in patients prescribed headgear and evaluate the impact of monitoring awareness, treatment duration, gender, and age on compliance levels. A total of 22 patients with Class II malocclusion wore the headgear integrated with the force and temperature sensitive Smartgear monitoring system (Smartgear, Swissorthodontics AG, Cham, Switzerland). Patients were instructed to wear the headgear for 13 h daily over a 3-month period.
View Article and Find Full Text PDFBackground: Although they have proven effective in the resolution of mild to moderate malocclusions, aligners demonstrate substantial limitations. More complex malocclusions therefore require a combination of auxiliaries, or a hybrid approach involving both aligners and fixed appliances, such as miniscrew-supported appliances or sectionals. This case report presents a 25-year-old female patient with a severe transversal discrepancy associated with an anterior open-bite tendency effectively treated with a tooth bone-borne palatal expander characterized by two expansion screws (tandem expander) and a hybrid treatment with aligners.
View Article and Find Full Text PDFBackground: The aim of the study was to compare the accuracy and reproducibility of three different 3D facial scanning systems, relying, respectively, on stereophotogrammetry, structured light and a smartphone app and camera.
Methods: Thirty subjects have been scanned with three different facial scanning systems, stereophotogrammetry, structured light and a smartphone app and camera. Linear measurements were compared with direct anthropometries measured on the patient's face, while the study of areas (forehead, tip of the nose, chin, right and left cheek) was evaluated by overlapping scans using the Geomagic Control X program.
Pharmaceuticals (Basel)
December 2023
Endometriosis is a common inflammatory disease affecting women of reproductive age, characterized by the growth of endometrial tissue beyond the uterus. In addition to gynecological manifestations, many endometriosis patients experience gastrointestinal symptoms, indicating a potential association between gut health and the disease. Recent studies have revealed alterations in the gut microbiota of individuals with endometriosis, including reduced diversity, microbial composition imbalances, and pathogenic bacteria.
View Article and Find Full Text PDFBackground: The widespread use of CAD/CAM transfer trays warrants evaluation of their accuracy as compared to PVS transfer trays.
Objectives: To quantify the accuracy of CAD/CAM and PVS transfer trays, investigating any differences between soft and hard trays CAD/CAM transfer trays.
Search Methods: Eight different databases (Scopus, Web of Science, PubMed, Google Scholar, ProQuest, Embase, Cochrane Library, ClinicalTrials.