Pharmacological actions and applications of safflower flavonoids.

Safflower ( L.), also known as Honghua, blueflower, or prickly safflower, is a medicinal herb effective in promoting blood circulation, dredging meridians, eliminating blood stasis, and relieving pain. Safflower contains complex chemical components, including flavonoids, alkaloids, organic acids, pigments, etc.

Production Methods, Biological Activity and Potential Application Prospects of Astaxanthin.

Astaxanthin (AST), a ketocarotenoid, is prevalent in aquatic life forms. AST has a variety of health-promoting effects, such as anti-oxidation, anti-cancer, eye protection, anti-inflammatory, immune regulation, skin care, anti-diabetes, neuroprotection, etc. It holds significant potential for applications in healthcare products, food additives, pharmaceuticals, cosmetics, and aquaculture.

The mechanism study of quercetin isolated from maxim. inhibiting ferroptosis and alleviating MAFLD through p38 MAPK/ERK signaling pathway based on lipidomics and transcriptomics.

Background: As a resource with a variety of medicinal and edible values, Maxim has been found to improve high-fat diet-induced metabolic-associated fatty liver disease (MAFLD).

Aim Of The Study: The aim of this study was to predict the main active metabolites in Maxim. Based on network analysis, and to explore and validate their potential mechanisms of action through lipidomics and transcriptomic techniques.

Endoplasmic reticulum stress and unfolded protein response in renal lipid metabolism.

The endoplasmic reticulum (ER) is a crucial cellular organelle involved in protein synthesis, folding, modification, and transport. Exposure to internal and external stressors can induce endoplasmic reticulum stress (ERS), leading to abnormal protein folding and ER malfunction. This stress can disrupt lipid synthesis, metabolism, and transport processes.

Extraction, detection, bioactivity, and product development of luteolin: A review.

Luteolin is a kind of natural flavonoid, widely existing in a variety of plants, has been revealed to have a wide range of biological activities. In recent years, the research results of luteolin are abundant. Here we review the latest research results of luteolin in order to provide new ideas for further research and development of luteolin.

Effect of hydroxy-α-sanshool on lipid metabolism in liver and hepatocytes based on AMPK signaling pathway.

Background: With the increasing awareness of the safety of traditional Chinese medicine and food, as well as in-depth studies on the pharmacological activity and toxicity of Zanthoxylum armatum DC. (ZADC), it has been found that ZADC is hepatotoxic. However, the toxic substance basis and mechanism of action have not been fully elucidated.

The bioactivity and applications of pomegranate peel extract: A review.

Pomegranate peel (PP) is a by-product in the processing of pomegranate products, which is usually discarded as a waste. However, a large number of researches have shown that pomegranate peel extract (PPE) is rich in a variety of phenolic substances, among which ellagic acid (EA), as one of the main active components, has significant biological activities, such as anti-oxidation, anti-tumor, anti-inflammatory, neuroprotection, anti-viral, and anti-bacterial. We analyzed the mechanism of EA's biological activity, and discussed its application in the food industry, for instance, food preservation, food additives, and functional foods.