Combined efficacy of Bacillus amyloliquefaciens CIM95 and melatonin in reducing anthracnose in strawberries (Fragaria × ananassa Duch.) by enhancing antioxidant activity and defense-related genes.

Anthracnose caused by Colletotrichum acutatum causes substantial losses in yield and fruit quality. This study aimed to investigate the combined effect of Bacillus-derived lipopeptides (LPs) and melatonin (MLT) on the suppression of anthracnose in strawberries. Compared with the control, ten different Bacillus species were screened for their antifungal activity in vitro, with Bacillus amyloliquefaciens CIM95 resulting in the greatest colony growth inhibition of C.

Liposomal Encapsulation in Food Systems: A Review of Formulation, Processing, and Applications.

Liposomal encapsulation is a crucial technique in food applications, offering protection and targeted delivery of bioactive compounds. This review focuses on the impact of thermodynamic factors on liposomal structures, specifically bilayers with large unilamellar vesicles and multilamellar vesicles. This study focuses on the chemical composition of liposomes, emphasizing the role of hydrophobic tails and sterols during phase transitions at various temperatures.

Marine Drug Design for Epitheliocytis Rendering AI-Assisted Bioisosteric Replacement of Salicin.

Epitheliocystis is a distinctive and relatively understudied bacterial infection of finfish skin and gill epithelia that occurs intracellularly and results in the enlargement of the host cells. The Candidatus Syngnamydia salmonis is a bacterial pathogen that affects fish, especially salmon species like trout and salmon. The production of Epitheliocystis by Candidatus Syngnamydia salmonis poses several challenges to the aquaculture industry.

Soluble Soybean Polysaccharide Improves Quality and Shelf Life of Peanut Butter.

Peanut butter, a plant-based spread, has gained global prominence due to the increasing consumer demand for nutritious convenience foods and the rising adoption of plant-based diets. However, oil separation during storage and transportation accelerates the oxidative rancidity and reduces the shelf life of peanut butter. Enhancing peanut butter stability by minimizing oil separation is therefore essential.

Production and characterization of a novel exopolysaccharide produced by Pediococcus acidilactici BCB1H isolated from traditional Chinese sauerkraut.

Exopolysaccharides (EPSs) produced by lactic acid bacteria (LAB) have been widely studied, but there has been a smaller amount of research focused on EPSs produced by Pediococcus acidilactici, an important LAB species commonly used in the food and biotechnology industries. In this study, production of the EPS BCB1H by P. acidilactici under different fermentation conditions was investigated, and kinetic models of bacterial growth, substrate consumption, and EPS synthesis were established.

Exploring the multifaceted probiotic potential of Lactiplantibacillus plantarum NMGL2, investigating its antimicrobial resistance profiles and bacteriocin production.

Background: Lactiplantibacillus plantarum is widely recognized for its probiotic and antimicrobial properties, making it a valuable candidate for food and clinical applications. Genomic characterization provides deeper insight into its potential health benefits and safety profile.

Aim: This study aimed to sequence and analyze the genome of L.

Natural gums (gum Arabic, guar gum and xanthan gum) as a promising source of prebiotics: a review on their functional roles and food applications.

Probiotics are live and non-pathogenic bacteria that confer several health benefits to the human body when ingested in adequate amounts. Unfortunately, viability and function of probiotics in food and beverages can be affected by a myriad of factors including product composition, processing and storage conditions. On the other hand, prebiotics are non-digestible carbohydrates (oligosaccharides) that can enhance viability or support growth of probiotics.

Metabolic and enzymatic characterization of linoleic acid biotransformation by Lactiplantibacillus plantarum NGML2 to conjugated linoleic acid and different metabolites.

Biotransformation is a biological process in which microorganisms or enzymes convert a substrate into a different chemical compound, often resulting in bioactive metabolites with therapeutic or industrial applications. Linoleic acid (LA) is a polyunsaturated fatty acid that has gained attention for its potential health benefits, including its role in modulating inflammation and oxidative stress. The ability of microorganisms to biotransform LA into bioactive metabolites, such as conjugated linoleic acid (CLA) isomers, provides an opportunity for the development of functional foods and nutraceuticals.

Using novel approaches to conjugate peptides of Macrotermes bellicosus and Curcuma longa for targeted intervention of irritable bowl diseases caused by tumor necrosis factor superfamily member 15 (TNFSF15).

This study presents an in-silico approach to develop targeted therapies for Irritable Bowel Disease (IBD) by focusing on TNFSF15. Peptides derived from Macrotermes bellicosus and Curcuma longa were selected, conjugated with the 50S ribosomal protein L7/L12 adjuvant, and analyzed for immunogenic potential. Gene expression analysis showed differential TNFSF15 expression in gastrointestinal tissues.

Inactivation mechanisms of carvacrol on Salmonella Typhimurium and its combined inhibitory effects with blue light-405 nm for chicken meat preservation.

Salmonella Typhimurium (S. Typhimurium) is a major contributor responsible for food contamination and foodborne illnesses. In this study, the antibacterial activity of natural compound carvacrol (CAR) against S.

In-vitro anti-inflammatory and antagonistic efficacy of polymyxin B capped silver nanoparticles in multi drug resistant Acinetobacter baumannii.

Multidrug resistant Acinetobacter baumannii is declared as crucial level precedence pathogen by World Health Organization that needs new and upgraded antibiotics for better treatment. Against a vast extent of microbes, many silver nanoparticles have displayed anti-microbial activity because of their numerous methods of antimicrobial actions. This study was aimed to isolate and characterize the Acinetobacter baumannii by using standard microbiological technique and to analyze the anti-inflammatory and antagonistic effect of PB capped AgNPs in isolated A.

Exploring the therapeutic potential of Thymus vulgaris ethanol extract: a computational screening for antimicrobial compounds against COVID-19 induced mucormycosis.

COVID-19-associated mucormycosis (CAM) has emerged as a concerning complication during the COVID-19 pandemic. In this study, we explored the potential of phytochemicals and flavonoids identified through High-Performance Liquid Chromatography (HPLC) analysis of Thymus vulgaris plant extract against key proteins of CAM, namely heat shock protein A5 (GPR78) and epidermal growth factor receptor (EGFR). HPLC analysis revealed the presence of bioactive compounds, including chlorogenic acid, cinamic acid, quercetin, coumaric acid, gallic acid, and syringic acid.

Elucidating the Phytochemical, Antibacterial, and Hepatoprotective Effects of Elaeagnus umbellata Leaf Extract Against Liver Injury in an Animal Model.

Elaeagnus umbellata, commonly known as autumn olive, is considered a medicinal plant of high value and belongs to the Elaeagnaceae family. It exhibits anti-ulcer, antimutagenic, antimicrobial, and neuroprotective properties. The leaves of E.

Green synthesis of silver and gold nanoparticles using seeds extract of Cichorium intybus and their comparative analysis with commercially available ointment for wound healing activity.

Wound healing is a complicated physiological process that involves several stages including hemostasis, inflammation, proliferation and repair to rebuild the integrity of the skin and subcutaneous tissue. Millions of people around the world are affected by poor wound healing, causing increased mortality rates and related costs. Immedicable wounds are a health problem because they directly affect the person's standard of living and produce an ultimatum to the health of people and the international economy because of the expensive medical treatment.

Enhancement of vitamin B12 in plant-based food through microbial fermentation-a sustainable food system.

Vitamin B12 deficiency represents a notable health concern, especially among individuals adhering to plant-based dietary patterns. Understanding the biochemical mechanisms of in-situ B12 synthesis by gut microbiome and prebiotic supplementation is important for microbial fermentation strategies. This article discusses the mechanisms and applications of microbial fermentation in augmenting B12 levels, focusing on its significance in fortifying plant-derived food products.

Computational design of a glycosylated multi-epitope vaccine against HAsV-1 and HAsV-2 astrovirus for acute gastroenteritis.

Human astrovirus (HAsVs) is a significant viral agent responsible for acute gastroenteritis, primarily affecting children. Among HAsVs serotypes, HAsVs - 1 and HAsVs-2 are the most virulent serotypes, contributing to severe gastrointestinal infections, and having limited therapeutics. This study aims to design multi-epitope vaccine candidate with predicted glycosylation sites against HAsVs-1 and HAsVs-2 utilizing an immunoinformatic approach.

Micro-nutrient sufficiency in mothers and babies: management of deficiencies while avoiding overload during pregnancy.

Pregnancy is a period characterized by extensive physiological changes in both the mother and fetus. During this period, the nutritional status of the mother has a profound and irreversible impact on her health and the growth and development of the fetus. The fetus depends exclusively on the mother and drives nutrients through the placenta.

Elucidating the exopolysaccharide biosynthesis in Pediococcus acidilactici BCB1H regulated by iron (Fe) using a multi-omics approach.

One of the vital functional biopolymers produced by lactic acid bacteria (LAB) is exopolysaccharide (EPS) that has been extensively studied, but less research has been done on the EPS production by pediococci. In this study, the EPS synthesis in Pediococcus acidilactici BCB1H regulated by Fe was investigated by a multi-omics method. Adding Fe (0.

In vitro simulated digestion of and microbial characteristics in colonic fermentation of polysaccharides from Lentinus edodes.

Lentinus edodes is widely cultivated and utilized globally, and Lentinus edodes polysaccharides (LEPs) are recognized as its primary bioactive components. However, the influence of regional variations LEPs has not yet been elucidated. This study aimed to investigate the differences in the and activity of LEPs from various sources following simulated in vitro digestion, as well as their impact on gut microbes.

Microbial evaluation of Melaleuca alternifolia essential oil for its antifungal activity against Trichophyton violaceum and its synergistic effects with ITZ and KTZ.

This study was designed to evaluate the effects of Melaleuca alternifolia essential oil for its antifungal activity as mono-therapeutic agent, and in combination with current antifungal agents, like itraconazole and ketoconazole. To assess the significance of TTO (Tea Tree Oil), ITZ (Itraconazole) and KTZ (Ketoconazole), for in vitro susceptibility pattern of dermatophyte, which was obtained from the cases of clinically examined dermatophytosis, attending the dermatology outpatient department of Sheikh Zayed Hospital. The tea tree essential oil was extracted through steam distillation method using 500 g of fresh Melaleuca alternifolia leaves from Lawrence Garden and obtained the yield of 3 mL that comes to be 0.

In vivo and in silico analysis of anti inflammatory, antipyretic and analgesic activity of methanolic extract of Nigella sativa.

Nigella Sativa (N. sativa) belongs to the family of Ranunculaceae and is an annual herb which is also known as black cumin or black seed. Since ancient times N.

Revolutionizing seafood packaging: Advancements in biopolymer smart nano-packaging for extended shelf-life and quality assurance.

Food packaging is one of the most important strategies to prevent food damage or spoilage during storage and the supply chain. Among various food types, seafood, a high-value product, is particularly vulnerable to post-harvest quality loss and microbial contamination during storage. Although current plastic-based packaging materials are durable, they pose a serious threat to the environment.

Fenugreek seeds as a natural source of L-arginine-encapsulated lipid nanoparticles against diabetes.

Diabetes, affecting over 10.5% of the global population, leads to severe health complications and economic burdens, highlighting the urgent need for effective therapeutic approaches. Current treatments are often insufficient, prompting the exploration of novel therapeutic agents and delivery mechanisms.

Genomic profiling of pediococcus acidilactici BCB1H and identification of its key features for Biotechnological innovation, food technology and medicine.

Lactic acid bacteria has been extensively used in food industry because of widespread properties and Pediococcus is among one of them. This study aims to conduct a comprehensive genomic analysis of Pediococcus acidilactici strain BCB1H to elucidate its genetic composition, functional elements, and potential biotechnological applications. The objectives include identifying key genomic features such as coding sequences, tRNA and rRNA genes, antibiotic resistance genes, and secondary metabolite biosynthetic gene clusters, which will highlight the adaptability and potential of P.