Cross-cultural adaptation and validation of the KOOS, JR questionnaire for assessing knee osteoarthritis in Spanish-speaking patients.

Purpose: The present study aims to translate, adapt and validate a Spanish version of the Knee Injury and Osteoarthritis Outcome Score, Joint Replacement (KOOS, JR), including a reliability and validity analysis in patients with knee osteoarthritis (OA).

Methods: This study conducted a prospective validation study following the six stages of the "Guidelines for the Process of Cross-Cultural Adaptation of Self-Report Measures". Psychometric testing was conducted in patients with knee osteoarthritis.

[Acute retinal necrosis by varicella zoster virus in an immunocompetent patient with therapeutic follow up by PCR].

We present the case of a 63-year-old immunocompetent man with unilateral acute retinal necrosis (ARN). He consulted for blurred vision, eye pain, photophobia, and headache. Papillitis and peripheal chorioretinitis associated with vasculitis and peripheral retinal ischemia was confirmed.

Sex-specific impact of patterns of imageable tumor growth on survival of primary glioblastoma patients.

Background: Sex is recognized as a significant determinant of outcome among glioblastoma patients, but the relative prognostic importance of glioblastoma features has not been thoroughly explored for sex differences.

Methods: Combining multi-modal MR images, biomathematical models, and patient clinical information, this investigation assesses which pretreatment variables have a sex-specific impact on the survival of glioblastoma patients (299 males and 195 females).

Results: Among males, tumor (T1Gd) radius was a predictor of overall survival (HR = 1.

Distinct Phenotypic Clusters of Glioblastoma Growth and Response Kinetics Predict Survival.

Purpose: Despite the intra- and intertumoral heterogeneity seen in glioblastoma multiforme (GBM), there is little definitive data on the underlying cause of the differences in patient survivals. Serial imaging assessment of tumor growth allows quantification of tumor growth kinetics (TGK) measured in terms of changes in the velocity of radial expansion seen on imaging. Because a systematic study of this entire TGK phenotype-growth before treatment and during each treatment to recurrence -has never been coordinately studied in GBMs, we sought to identify whether patients cluster into discrete groups on the basis of their TGK.

Sex differences in GBM revealed by analysis of patient imaging, transcriptome, and survival data.

Sex differences in the incidence and outcome of human disease are broadly recognized but, in most cases, not sufficiently understood to enable sex-specific approaches to treatment. Glioblastoma (GBM), the most common malignant brain tumor, provides a case in point. Despite well-established differences in incidence and emerging indications of differences in outcome, there are few insights that distinguish male and female GBM at the molecular level or allow specific targeting of these biological differences.

Theoretical and numerical assessment of maximally allowable power-density averaging area for conservative electromagnetic exposure assessment above 6 GHz.

The objective of this paper is to determine a maximum averaging area for power density (PD) that limits the maximum temperature increase to a given threshold for frequencies above 6 GHz. This maximum area should be conservative for any transmitter at any distance >2 mm from the primary transmitting antennas or secondary field-generating sources. To derive a generically valid maximum averaging area, an analytical approximation for the peak temperature increase caused by localized exposure was derived.

EXPOSURE ASSESSMENT OF PORTABLE WIRELESS DEVICES ABOVE 6 GHz.

The emerging 5 G wireless devices working at frequencies above 6 GHz are expected to have antenna arrays formed by dipoles, slots, patches or their combination. At lower frequencies, the accepted criteria for exposure compliance is stated in terms of specific absorption rate. IEEE and ICNIRP are adopting epithelial or transmitted power density (PD through body surface) as the dosimetric reference for frequencies above 6 GHz, which entails the measurement of free space PD.

Inverse Kinematics for Upper Limb Compound Movement Estimation in Exoskeleton-Assisted Rehabilitation.

Robot-Assisted Rehabilitation (RAR) is relevant for treating patients affected by nervous system injuries (e.g., stroke and spinal cord injury).

Self-administered versus interview-based questionnaires among patients with intermittent claudication: Do they give different results? A cross-sectional study.

Context And Objective: Many clinical investigations use generic and/or specific questionnaires to obtain information about participants and patients. There is disagreement about whether the administration method can affect the results. The aim here was to determine whether, among patients with intermittent claudication (IC), there are differences in the Walking Impairment Questionnaire (WIQ) and European Quality of Life-5 Dimension (EQ-5D) scores with regard to: 1) the questionnaire administration method (self-administration versus face-to-face interview); and 2) the type of interviewer (vascular surgeon, VS, versus general practitioner, GP).

Gate-controlled mid-infrared light bending with aperiodic graphene nanoribbons array.

Graphene plasmonic nanostructures enable subwavelength confinement of electromagnetic energy from the mid-infrared down to the terahertz frequencies. By exploiting the spectrally varying light scattering phase at the vicinity of the resonant frequency of the plasmonic nanostructure, it is possible to control the angle of reflection of an incoming light beam. We demonstrate, through full-wave electromagnetic simulations based on Maxwell equations, the electrical control of the angle of reflection of a mid-infrared light beam by using an aperiodic array of graphene nanoribbons, whose widths are engineered to produce a spatially varying reflection phase profile that allows for the construction of a far-field collimated beam towards a predefined direction.

Hygehos Home: an innovative remote follow-up system for chronic patients.

This paper describes an innovative architecture for the remote follow-up of the health of chronic patients, and its implementation which is called Hygehos Home. The main purpose of the system is to enhance the quality of the daily healthcare practice, by means of bringing both patient and medical professionals closer to each other and by empowering the patient in the healing process. On the one side, Hygehos Home is a platform which gives the patient access to a set of personalized e-Health services using different channels such as web or smartphone.

Differences between women and men with intermittent claudication: a cross-sectional study.

Background: Intermittent claudication (IC) and its consequences have customarily been underestimated in women. Our study aimed to determine the differences on functional and quality-of-life issues between women and men in a large group of claudicants.

Methods: This study was an observational, cross-sectional, nonrandomized, multicenter study of 1,641 claudicants (406 women).

[A case of mycotic keratitis due to Fusarium solani in Valdivia, Chile].

Background: Keratomycosis is one of the most prevalent ophthalmic infections, which needs a specific treatment depending on the nature of the infecting fungus. The prognosis is usually severe and depends on an early diagnosis and suitable therapy.

Case Report: We describe a case of keratitis due to Fusarium solani in a patient from a rural area, who, between May and October 2011, suffered a corneal trauma caused by dust particles in Valdivia, Chile.

Feasibility and reliability of dynamic postural control measures in children in first through fifth grades.

Purpose/background: Although dynamic postural control is a prerequisite to the development of fundamental movement skills in children, few studies have examined the feasibility and reliability of assessment techniques that measure dynamic postural control in youth under 13 years of age. Therefore, the purpose of this study was to determine the feasibility and reliability of the Lower Quarter Y Balance Test (YBT-LQ) in children and to examine the reproducibility of these measures across developmental periods of childhood.

Methods: 188 subjects in first through fifth grades (age = 6.

Diabetes mellitus and intermittent claudication: a cross-sectional study of 920 claudicants.

Introduction: Diabetes mellitus (DM) and intermittent claudication (IC) are frequently associated health conditions. Our hypothesis is that the nature, severity and quality of life (QoL) of patients with IC and DM are worse than those of claudicant patients without diabetes.

Material And Methods: An observational, cross-sectional and multicentre study of 920 patients with IC, divided into two groups: diabetic (n = 477) and non-diabetic (n = 443).

Validation of the Walking Impairment Questionnaire for Spanish patients.

Background: The Walking Impairment Questionnaire (WIQ) is a short, easy to complete, disease-specific questionnaire to assess intermittent claudication. A Spanish version of the WIQ for Hispanic Americans has recently been validated in Texas, but it needs to be validated for European Spanish people.

Patients And Methods: After translation and cultural adaptation of the WIQ, 920 patients with intermittent claudication (ankle brachial index < 0.

Negative impact of deep venous thrombosis on chronic venous disease.

Introduction: There are several conditions that may cause chronic venous disease (CVD). It is not known whether the aetiology of CVD can predict disease severity and quality of life (QoL). Our objective is that the severity and QoL of patients with CVD secondary to DVT is different from those without prior DVT.

Virtual reality system in conjunction with neurorobotics and neuroprosthetics for rehabilitation of motor disorders.

Cerebrovascular accidents (CVA) and spinal cord injuries (SCI) are the most common causes of paralysis and paresis with reported prevalence of 12,000 cases per million and 800 cases per million, respectively. Disabilities that follow CVA (hemiplegia) or SCI (paraplegia, tetraplegia) severely impair motor functions (e.g.