Publications by authors named "Dylan Harries"

Background: Periprosthetic joint infection (PJI) following total knee arthroplasty (TKA) is a serious complication associated with notable loss of function, impaired quality of life, and excess short-term mortality. In this study, we aimed to report the impact of PJI on long-term mortality and its associated risk factors.

Methods: Using data from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR), we used Kaplan-Meier estimates of survivorship and standardized mortality ratios (SMRs) based on Australian period life tables to describe mortality rates following revision for PJI, aseptic revisions (excluding those for fracture), and unrevised primary TKA.

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Background: While the morbidity associated with revision total hip arthroplasty (THA) or periprosthetic infection (PJI) has been well characterized, less is known about the risk of mortality. With this study, we aimed to determine the long-term mortality associated with revision THA for PJI and associated risk factors.

Methods: Data from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) were used to study mortality associated with THA procedures for osteoarthritis and subsequent revisions from September 1999 through December 2022.

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Objectives: In October 2022, Australia introduced individual targets for total care and registered nurse (RN) minutes for long-term care facilities based on the assessed care needs of their residents. This study examined associations between facility characteristics and the extent to which care minute targets are met, and determined whether care minutes were associated with residents' experience and quality measures.

Design: Ecological cross-sectional study using pooled publicly available data from 5 quarterly reporting periods between January-March 2023 and January-March 2024.

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Background: Reverse total shoulder arthroplasty (rTSA) is being increasingly used in the treatment of comminuted or unreconstructible proximal humerus fractures. It is currently unclear if cementless rTSA have equivocal revision rates, mortality, and functional outcomes compared to cemented or cementless rTSA.

Methods: Two data sources were used for this study.

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Aims: There is uncertainty over whether robotic-assisted surgery (RAS) or kinematic alignment (KA) improves outcomes in total knee arthroplasty (TKA). The Robotic-Assisted Surgery and Kinematic ALignment in TKA trial (RASKAL) is a registry-nested, multicentre, randomized, blinded, 2 × 2 factorial trial involving approximately 300 TKA patients. RASKAL will assess the effectiveness of RAS, KA, or both to improve clinical, operative, functional, radiological, and survivorship outcomes when compared to computer-assisted surgery (CAS) and mechanical alignment (MA), respectively.

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Background: The revision rates of 4 modern (currently used) polyethylene glenoid designs in anatomic total shoulder arthroplasty (stemmed and stemless) for osteoarthritis (OA) are compared from a national arthroplasty registry to model predictive variables.

Materials And Methods: The study period was January 1, 2008, to December 31, 2023. The study population included all primary anatomic total shoulder arthroplasty (aTSA) procedures undertaken for OA.

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Background: Although there is a known correlation between obesity and revision risk following total knee arthroplasty (TKA), there is an ongoing debate regarding the appropriateness of denying TKA solely based on the body mass index (BMI) of a patient. Our aim was to determine whether a patient's American Society of Anesthesiologists (ASA) class predicts their risks of early all-cause revision and revision for periprosthetic joint infection (PJI) following primary TKA, independent of their BMI.

Methods: Data from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) were obtained regarding all patients who underwent primary TKA for osteoarthritis in Australia from January 1, 2015, to December 31, 2022.

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Background: Proximal humerus fractures (PHF) are common with approximately 30% requiring surgical intervention. This ranges from open reduction internal fixation (ORIF) to shoulder arthroplasty (including hemiarthroplasty, total shoulder arthroplasty (TSA), reverse total shoulder arthroplasty (RTSA)). The aim of this study was to assess trends in operative interventions for PHF in an Australian population.

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Background: This study aimed to determine the revision outcome between a centrally fixed stemless anatomic design and other total anatomic shoulder replacements using data from a large national arthroplasty registry.

Methods: The study period was from December 2011 to December 2022 and included three cohorts; primary Affinis stemless anatomic (AFS), all other primary total stemless anatomic (sTSA) and primary total stemmed anatomic shoulder arthroplasty (aTSA). The endpoint was all-cause revision using cumulative percent revision (CPR).

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Background: Periprosthetic joint infection is a devastating and severe complication of total knee arthroplasty (TKA). The Australian Joint Registry reports an increasing number of debridement, antibiotics, and implant retention (DAIR) procedures, underscoring the need to comprehend outcomes for informed treatment decisions. This study aimed to determine the outcome of DAIR procedures, evaluate time since primary TKA, and identify patient-related factors associated with DAIR failure.

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Background: Total hip arthroplasty (THA) is a well-established treatment for symptomatic hip osteoarthritis (OA). The use of computer navigation in THA aims to achieve the reconstruction of the joint more consistently and precisely. The aim of this study was to contrast patient-reported outcome measures (PROMs) for THA procedures with and without commercially available navigation technologies.

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Article Synopsis
  • This study analyzed shoulder arthroplasty procedures from a national registry to evaluate revision rates for osteoarthritis, focusing on the best options for men and women.
  • Three types of shoulder arthroplasties were compared: stemless shoulder arthroplasty (slTSA), stemmed shoulder arthroplasty (stTSA), and cementless reverse shoulder arthroplasty (rTSA), with cumulative percent revision (CPR) calculated over a 7-year period.
  • Results indicated that while all methods had similar revision rates, rTSA showed significantly lower rates than slTSA after 9 months; gender also played a role, with women experiencing lower revision rates than men for stTSA and rT
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Importance: Structured education and exercise therapy programs have been proposed to reduce reliance on total knee replacement (TKR) surgery and improve health care sustainability. The long-term cost-effectiveness of these programs is unclear.

Objectives: To estimate the lifetime cost-effectiveness of implementing a national structured education and exercise therapy program for individuals with knee osteoarthritis with the option for future TKR compared with usual care (TKR for all).

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Background: Technology (navigation and robotics) usage during total knee arthroplasty (TKA) is often supported by literature involving high-volume surgeons and hospitals, but the value of technology for lower-volume surgeons is uncertain. This study aimed to determine if there was a relationship among surgeon volume, technology usage, and revision rate when using an optimal prosthesis combination (OPC).

Methods: Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) data were obtained from January 1, 2008, to December 31, 2022, for all primary TKA procedures performed for osteoarthritis using an OPC by a known surgeon ≥5 years after their first recorded procedure.

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Objectives: A Star Rating system (1 to 5 stars) of long-term care facilities in Australia is based on 4 sub-categories: compliance, quality measures, residents' experience, and staffing. The objectives were to examine associations between facility characteristics and the odds of receiving a 4- or 5-star rating, and changes in ratings between the earliest reporting period (October-December 2022) to the most recent (April-June 2023).

Design: Cross-sectional, ecological study, with an additional longitudinal component.

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Background: Population-level data from national arthroplasty registries enable the use and outcomes of arthroplasty procedures to be monitored over time. This study aimed to describe the demographics, indications, and outcomes (up to 15 years) for radial head arthroplasty (RHA) procedures in Australia, as well as the factors associated with an increased likelihood of revision.

Methods: Individual-level deidentified data on demographics and surgery characteristics, including revision surgery, were obtained from the Australian Orthopaedic Association National Joint Replacement Registry for all primary isolated RHA procedures that had been performed from 2007 to 2021.

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Article Synopsis
  • The study investigates the impact of surgeon-related factors on revision rates after total hip arthroplasty (THA), using data from the Australian Orthopaedic Association National Joint Replacement Registry.
  • It aims to determine if differences in revision rates disappear when comparing surgeries using either the best or worst-performing prostheses and how these rates vary among surgeons.
  • The analysis involves over 302,000 THA procedures from 476 surgeons, focusing on how the type of prosthesis and surgeon expertise influence overall revision outcomes.
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Importance: Despite increased use of antibiotic-loaded bone cement (ALBC) in joint arthroplasty over recent decades, current evidence for prophylactic use of ALBC to reduce risk of periprosthetic joint infection (PJI) is insufficient.

Objective: To compare the rate of revision attributed to PJI following primary total knee arthroplasty (TKA) using ALBC vs plain bone cement.

Design, Setting, And Participants: This international cohort study used data from 14 national or regional joint arthroplasty registries in Australia, Denmark, Finland, Germany, Italy, New Zealand, Norway, Romania, Sweden, Switzerland, the Netherlands, the UK, and the US.

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Background: The stemmed anatomic total shoulder arthroplasty is the gold standard in the treatment of glenohumeral osteoarthritis. However, the use of stemless total shoulder arthroplasties has increased in recent years. The number of revision procedures are relatively low, and therefore it has been recommended that national joint replacement registries should collaborate when comparing revision rates.

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Article Synopsis
  • The study aimed to evaluate and compare the health-related quality of life outcomes of the first and second knee procedures in patients receiving staged bilateral total knee arthroplasty for osteoarthritis.
  • Researchers analyzed data from 635 participants between January 2013 and January 2021, focusing on the Oxford Knee Score and other quality of life metrics six months after each knee surgery.
  • Results showed minimal differences between the first and second knee outcomes overall, but specific improvements in mobility and pain were noted after the second surgery, indicating better cumulative quality of life post-replacement.
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Background: We compared revision rates and reasons for revision for primary total knee arthroplasty (TKA) performed for osteoarthritis with and without tibial stem extensions.

Methods: Data from the Australian Orthopaedic Association National Joint Replacement Registry were used to compare all-cause revision, reason, and type of revision between primary TKA using stemmed tibial prostheses and non-stemmed prostheses.

Results: All-cause revision for TKA with stem extension was higher for the first 6 months (hazard ratio [HR] 1.

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Article Synopsis
  • Monoblock ceramic cups, like the DeltaMotion, are designed for total hip arthroplasty (THA) to provide better movement and stability, particularly for young and active patients.
  • A study analyzed data from over 486,000 THA procedures to compare the DeltaMotion cup with modular designs, focusing on revision rates and issues like dislocation and ceramic breakage.
  • The DeltaMotion cup showed lower overall revision rates and significantly fewer problems related to dislocation and ceramic breakage compared to modular bearings, indicating its effectiveness despite being discontinued.
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Background: Polished baseplates were introduced into total knee arthroplasty (TKA) systems to reduce the incidence of backside wear. In 2004, a fixed-bearing knee arthroplasty system underwent a change in baseplate material from matt titanium to polished cobalt-chrome (CoCr) with the intention to reduce backside wear. Other design aspects were left unchanged.

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Background: We investigated if the use of augmented tibial fixation with stems in primary total knee arthroplasty (TKA) in obese patients was associated with a difference in reason for revision, type of revision, or overall revision rate.

Methods: Data from the Australian Orthopaedic Association National Joint Replacement Registry compared reason for revision, rate, and type of revision between primary TKA using stemmed tibial prostheses to nonstemmed prostheses, stratified by body mass index (BMI) and obesity. The cumulative percent revision was obtained using the Kaplan-Meier method, and Cox proportional hazards models estimated hazard ratios (HRs) adjusted for age and sex with 95% confidence intervals (CIs).

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Background And Purpose: Antibiotic-loaded bone cement (ALBC) and systemic antibiotic prophylaxis (SAP) have been used to reduce periprosthetic joint infection (PJI) rates. We investigated the use of ALBC and SAP in primary total knee arthroplasty (TKA).

Patients And Methods: This observational study is based on 2,971,357 primary TKAs reported in 2010-2020 to national/regional joint arthroplasty registries in Australia, Denmark, Finland, Germany, Italy, the Netherlands, New Zealand, Norway, Romania, South Africa, Sweden, Switzerland, the UK, and the USA.

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