Tris- and tetrakis-iridoids: a review on their occurrence in plants, chemophenetic value and pharmacological activities.

In this review paper, the occurrence in plants, structural variability, possible chemophenetic value and pharmacological activities of tris- and tetrakis-iridoids were reported altogether for the first time. In particular, the exact number of these compounds discovered so far was presented, listing their names and detailing the plant species of their recovery with their organs and belonging family as well as the methodologies adopted for their extraction, separation and identification. The structural characteristics of tris- and tetrakis-iridoids were displayed with a particular focus on their specific peculiarities.

Unveiling the Chemical Profile of Teucrium chamaedrys subsp. gracile (Batt.) Rech.F. dried Aerial Parts From Algeria.

In this paper, the first phytochemical analysis on Teucrium chamaedrys subsp. gracile was reported. The dried aerial parts collected in Algeria were studied, and the analysis was conducted using different techniques: gas chromatography/mass spectrometry (GC/MS) for the fatty acid content, headspace solid-phase microextraction-GC-MS for the volatile composition, column chromatography along with nuclear magnetic resonance spectroscopy, and MS for non-volatile pattern characterization.

Phytochemical analysis and chemophenetic evaluation of L.

In this work, the first complete phytochemical analysis ever performed on a European population of L., led to the identification of twelve metabolites from its leaf ethanolic extract: pheophytin (), verbascoside (), leucosceptoside A (), apigenin (), kaempferol (), 5-hydroxy-8--loganin (), lamiide (), penstemoside (), 5-deoxy-pulchelloside I (), quinic acid (), vanillic acid () and glycerol (). Their chemophenetic value was evaluated individuating and even suggesting chemophenetic markers at various levels.

Phytochemical Analysis and Biological Activities of W.G.Jones, K.D.Hill & J.M.Allen Leaves Collected in the Botanical Garden of Rome.

In this work, a preliminary screening of the bioactivities of an ethanolic extract obtained from the leaves of W.G.Jones, K.

A new isolation of vincamajine from subsp. Stearn.

The continuation of the phytochemical analysis to determine the alkaloid content of subsp. Stearn, led to the isolation of the further compound vincamajine () which was reported from the species for the first time during this study. Its structure was established by means of extensive NMR, IR and MS analyses which are completely reported in this paper for the first time.

-Iridoids: Occurrence, Chemophenetic Evaluation and Biological Activities-A Review.

In this work, the first review paper about -iridoids was presented. In particular, their detailed occurrence, chemophenetic evaluation and biological activities were reported. To the best of our knowledge, two hundred and eighty-eight -iridoids have been evidenced so far, bearing different structural features, with the link between two -iridoids sub-units as the major one.

Phytochemical analysis on the female cone of Hook.

In this work, the first phytochemical analysis ever performed on a whole cone of Hook. is presented. This was carried out by means of column chromatography, NMR spectroscopy and MS spectrometry on the female cone, evidencing the presence of forty metabolites, thirty-three of which are primary whilst the remaining are non-volatile secondary.

Phytochemical analysis and biological activities of the aerial parts of Odontites vulgaris Moench.

In this work, the first specific phytochemical analysis on Odontites vulgaris Moench collected in Central Italy was performed. The aerial parts ethanolic extract was studied and eight compounds were identified: pheophytin a (1), aucubin (2), catalpol (3), shanzhiside methyl ester (4), melampyroside (5), 8-epi-loganin (6), caryoptoside (7) and quinic acid (8). To the best of our knowledge, in this study, compounds (7-8) resulted to be isolated from the genus for the first time.

Evaluation of the Antifungal and Antiproliferative Properties of the Lichen DC. Extracts and Main Components.

In this work, phytochemical analysis on different extracts of DC. was reported using different techniques with respect to the past. Twenty volatile and three non-volatile compounds were identified, some of which were found in this species for the first time.

Occurrence and Biological Activities of Seco-Iridoids from Jasminum L.

In this paper, the first complete review on the seco-iridoids from the genus Jasminum L. was presented. In particular, their occurrence in the genus was detailed together with their biological activities.

Comparison of the metabolic profile of pecan nuts cultivars [ (Wangenh.) K. Koch] by NMR spectroscopy.

Pecan nuts ( (Wangenh.) K. Koch) contain the highest number of phytochemicals of all nuts, are a natural source of unsaturated fatty acids and other nutrients and can be considered an important addition to the Mediterranean diet al.

Phytochemical Analysis and Antileukemic Activity of Alkaloid-Enriched Extracts from (Stearn) Pignatti.

(Stearn) Pignatti, known as Sardinian periwinkle, is widely diffused in Sardinia (Italy). This species contains indole alkaloids, which are known to have a great variety of biological activities. This study investigated the antileukemic activity against a B lymphoblast cell line (SUP-B15) of alkaloid-rich extracts obtained from plants grown in Italy, in Iglesias (Sardinia) and Rome (Latium).

Leucosceptosides A and B: Two Phenyl-Ethanoid Glycosides with Important Occurrence and Biological Activities.

In this review paper, the occurrence in the plant kingdom, the chemophenetic value and the biological activities associated with two specific phenyl-ethanoid glycosides, , leucosceptoside A and leucosceptoside B, were reported. This is the first work ever conducted on such a subject. Analysis of the literature data clearly led to three important conclusions: leucosceptoside A is much more common in plants than leucosceptoside B; leucosceptoside A exerts more biological activities than leucosceptoside B even if nothing can be generally concluded about which one is actually the most potent; neither of these compounds can be used as a chemophenetic marker.

Phytochemical analysis on the aerial parts of L. with aspects of chemosystematics and ethnobotany.

The phytochemical analysis on the aerial parts of L. collected from a new population in Central Italy, led to the identification of eight compounds, i.e.

Phytochemical analysis on the leaves of J.F. Bailey & C.T. White.

The first phytochemical analysis on the leaves of J.F. Bailey & C.

A Systematic Review on Phytochemistry, Ethnobotany and Biological Activities of the Genus Bunium L.

The aim of this review article is to present, for the first time, an appraisal of the phytochemical, ethnobotanical and pharmacological data on Bunium species. The literature search was conducted using the Scopus, Google Scholar and PubMed databases. The genus Bunium has been found to produce both essential oil (EO), mainly comprising monoterpenes and sesquiterpenes, and non-volatile components mainly coumarins and flavonoids.

The Genus Juss.: Phytochemistry and Bioactivities-A Review.

Herein, a comprehensive review is given focusing on the chemical profiles of the essential oils (EOs), non-volatile compounds, ethnobotany, and biological activities of different (Rutaceae family) species. To gather the relevant data, all the scientific databases, including Scopus, ISI-WOS (Institute of Scientific Information-Web of Science), and PubMed and highly esteemed publishers such as Elsevier, Springer, Taylor and Francis, etc., were systematically retrieved and reviewed.

An overview of the genus Paláu (Verbenaceae): Essential oil composition, ethnobotany and biological activities.

Paláu is an important herbal genus from the Verbenaceae family and possesses numerous remedial properties in the folk medicine of Asian, European, and, in particular, South American countries. Only a few reports have discussed some phytochemical characteristics associated with species. Right the lack of an exhaustive report prompted us to organize this review article.

Phytochemical Analysis and Biological Activities of the Ethanolic Extract of Vahl Flowering Aerial Parts Collected in Central Italy.

In this paper, the first phytochemical analysis of the ethanolic extract of Vahl flowering aerial parts collected in Italy and its biological activities were reported. Eleven compounds were identified i.e.

Phytochemical analysis on the seeds of a new Iranian Forssk. population specimen.

In this paper, the phytochemical analysis of the seeds of a new Iranian Forssk. population exemplar is reported. This phytochemical analysis was carried out by means of hydroalcoholic maceration, column chromatography, NMR and MS analyses and led to the isolation of sixteen compounds belonging to five different classes of natural compounds.

Harpagide: Occurrence in plants and biological activities - A review.

In this review article, the occurrence of harpagide in the plant kingdom and its associated biological activities are presented and detailed for the first time. The presence of harpagide has been reported in several botanical families within Asteridae, and harpagide has been observed to exert a wide number of biological activities such as cytotoxic, anti-inflammatory, and neuroprotective. These results show how harpagide can be recovered from several natural sources for several pharmacological purposes even if there is a lot to still be studied.

Phytochemical analysis of Franch. and cholinesterase inhibitory activity of its dihydrochalcones.

One flavonoid (quercetin, ) and three dihydrochalcones (6''---hydroxybenzoyl-davidioside, , 4'--methyl-davidioside, , and davidioside, ) were isolated from the leaves and young branches of Franch. All the structures were identified by comparison of their spectroscopic data (NMR and MS) with those present in literature. In addition, compounds were evaluated for their cholinesterase inhibitory (ChEI) activity, for the first time.

Phytochemistry, Chemotaxonomy, and Biological Activities of the Araucariaceae Family-A Review.

In this review article, the phytochemistry of the species belonging to the Araucariaceae family is explored. Among these, in particular, it is given a wide overview on the phytochemical profile of genus, for the first time. In addition to this, the ethnopharmacology and the general biological activities associated to the Araucariaceae species are singularly described.

Phytochemical Analysis and Trypanocidal Activity of Desr.

The rationale inspiring the discovery of lead compounds for the treatment of human parasitic protozoan diseases from natural sources is the well-established use of medicinal plants in various systems of traditional medicine. On this basis, we decided to select an overlooked medicinal plant growing in central Italy, Desr. (Lamiaceae), which has been used as a traditional remedy against protozoan diseases, and to investigate its potential against Human African trypanosomiasis (HAT).

A new diterpene and other compounds from the unripe female cones of .

In this work, the first phytochemical analysis ever performed on the unripe female cones of W. G. Jones, K.