Publications by authors named "Khellaf Rebbas"

The present study aimed to investigate, for the first time, the chemical composition of the essential oil from the aerial part of Scabiosa daucoïdes Desf (Caprifoliaceous) by GC-FID and GC-MS methods. The essential oil was extracted using the steam distillation technique. Thirty-eight components were identified, representing 76.

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In this paper, the first phytochemical analysis on Teucrium chamaedrys subsp. gracile was reported. The dried aerial parts collected in Algeria were studied, and the analysis was conducted using different techniques: gas chromatography/mass spectrometry (GC/MS) for the fatty acid content, headspace solid-phase microextraction-GC-MS for the volatile composition, column chromatography along with nuclear magnetic resonance spectroscopy, and MS for non-volatile pattern characterization.

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The genus Miller, belonging to the Fabaceae family, has wide distribution ranging from Europe to Mongolia and Himalaya, Arabian Peninsula, Ethiopia, with eastern Mediterranean area and western Asia considered as the centres of diversity. Plants from this genus have been used for centuries around the world, as forage for ruminant animals, both for grazing and as hay. The use of some species in traditional medicine has been also documented.

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This study explores the potential of Thymus ciliatus as a natural source of bioactive compounds by investigating its chemical composition and in vitro biological activities, including antioxidant, antimicrobial, antidiabetic, and anti-Alzheimer properties. The analysis of the essential oil was performed using gas chromatography-mass spectrometry revealing α-terpinenyl acetate (18.74%) and camphor (10.

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This study represents the first investigation of the volatile composition of (Convolvulaceae) collected in Algeria, using headspace solid-phase microextraction and gas chromatography/mass spectrometry (HS-SPME-GC/MS). This technique allowed the identification of 44 compounds, constituting 96.9% of the total components.

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The study examines the chemical composition and antimicrobial properties of petroleum ether and hydro-methanolic extracts of Achillea santolina from Algeria. Chemical profiling was performed using high-performance liquid chromatography with diode array detection for the hydro-methanolic extract and gas chromatography-mass spectrometry for the petroleum ether extract. Antibacterial and antifungal activities were evaluated using the disc diffusion method and broth dilution technique.

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This research explored the impact of methanolic extracts from the fruits and leaves of L., a rare Algerian species, on several enzymes, focusing on tyrosinase, α-amylase, α-glucosidase, and cholinesterases, as well as their antioxidant potential assays, including phosphomolybdenum, DPPH, ABTS, CUPRAC, FRAP, and MCA. HPLC-DAD analysis identified chlorogenic acid, rosmarinic acid, hesperidin, and quercetin as predominant phenolic components.

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The genus (Plumbaginaceae) includes several species of perennial herbs and shrubs belonging to a particular type of halophytes, known as 'recretohalophytes'. species are widely distributed in the Mediterranean region, mainly in the North-Eastern and Southern countries and several bioactivities have been well documented. In the present study, the chemical composition of the essential oil (EO) of the aerial parts of (L.

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Desf. (Apiaceae) is a plant endemic to North Africa, including Algeria. It is used as natural medicine, due to its anti-inflammatory, antioxidant and hepatoprotective properties.

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The search for new bioactive substances with anticancer activity and the understanding of their mechanisms of action are high priorities in the research effort toward more effective cancer treatments. In this article, we analyzed, for the first time, the chemical composition of the essential oil (EO) hydrodistilled from the aerial parts of Ten. (Leguminosae) by GC-MS.

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Article Synopsis
  • Several specialized plant metabolites can inhibit enzymes, and this study focused on the phytochemical composition and biological activity of a specific plant.
  • A new lignan compound, rhanteriol, along with seven known metabolites, was isolated using chromatographic techniques, and their ability to inhibit cholinesterase and carbohydrate-hydrolyzing enzymes was tested in vitro.
  • Rhanteriol showed significant inhibitory effects on key enzymes related to diabetes and neurodegeneration, suggesting its potential for developing treatments for these conditions.
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Ethnopharmacological Relevance: A rising resort to herbal therapies in Crohn's disease (CD) alternative treatments has been recently observed due to their remarkable natural efficiency. In this context, the weed plant Ambrosia maritima L., traditionally known as Hachich el Aouinet in Algeria and as Damsissa in Egypt and Sudan, is widely used in North African folk medicine to treat infections, inflammatory diseases, gastrointestinal and urinary tract disturbances, rheumatic pain, respiratory problems, diabetes, hypertension and cancer.

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The phytochemical and biological properties of Poir L. (Fabaceae) were investigated for the first time in this study. The chemical composition of the essential oil obtained from the aerial parts was analysed by GC-MS.

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Ethnopharmacological Relevance: Ethnoveterinary medicine is vastly under-documented, especially in North Africa, where livestock care is increasingly medicalised. Despite evidence of the interdependence of ethnoveterinary practices and ethnomedicine for human care, the overlap between these two systems and the possible drivers of similarity are rarely addressed in ethnopharmacological literature. Here, we present the first quantitative comparison of remedies used to treat human and animal health among a pastoral society.

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The mechanisms shaping island biotas are not yet well understood mostly because of a lack of studies comparing eco-evolutionary fingerprints over entire taxonomic groups. Here, we linked community structure (richness, frequency and nestedness) and genetic differentiation (based on mitochondrial DNA) in order to compare insular butterfly communities occurring over a key intercontinental area in the Mediterranean (Italy-Sicily-Maghreb). We found that community characteristics and genetic structure were influenced by a combination of contemporary and historical factors, and among the latter, connection during the Pleistocene had an important impact.

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