Graft Angle, Intercondylar Notch Osteophytes, and Tibial Tunnel Abnormalities Influence Graft Impingement After Anterior Cruciate Ligament Reconstruction: A Retrospective MRI-Based Study.

Graft impingement is a critical cause of anterior cruciate ligament reconstruction (ACLR) failure. Identifying its contributing factors is essential for improving surgical outcomes. This retrospective study aimed to evaluate the incidence of graft impingement following ACLR using magnetic resonance imaging (MRI) and to investigate potential anatomical and surgical risk factors.

Enhanced CT-Based Delta-Radiomics: Predicting Lymphovascular and Perineural Invasion in Rectal Cancer Preoperatively.

To construct and validate a multi-phase contrast-enhanced computed tomography delta-radiomics signature for preoperatively predicting lymphovascular invasion (LVI) and perineural invasion (PNI) in patients with rectal cancer (RC). This study retrospectively enrolled 519 patients with RC between January 2017 and December 2022, with patients assigned to the training (n = 363) or validation (n = 156) sets. Radiomic features were extracted from routine scanning (A0), the arterial phase (A1), and the venous phase (A2).

New imaging findings of tumor invasion into brain tissue: "Peritumoral Hyperintense Enhancement Sign".

Introduction: This study investigated the MRI characteristics of meningiomas and brain metastases, exploring the relationship between the "Peritumoral Hyperintense Enhancement Sign" and brain invasion, and its clinical implications for treatment planning.

Methods: A multicenter retrospective analysis was conducted on 24 cases (17 brain metastases and 7 meningiomas), examining the MRI features of the "Peritumoral Hyperintense Enhancement Sign" and corresponding histopathological characteristics.

Results: All cases demonstrated peritumoral enhancement: 8 cases exhibited flame-shaped enhancement, 12 showed crescentic enhancement, and 4 displayed both patterns.

Study of the antivirus patch testing problem through optimal control modeling.

The lag of antivirus (AV) software development relative to malware development makes it necessary to constantly release AV patches. In practice, an AV patch can be deployed on an organization's intranet only when it passes compatibility test. In this context, a subset of hosts may be assigned to perform the test.

A nomogram based on CT intratumoral and peritumoral radiomics features preoperatively predicts poorly differentiated invasive pulmonary adenocarcinoma manifesting as subsolid or solid lesions: a double-center study.

Background: The novel International Association for the Study of Lung Cancer (IASLC) grading system suggests that poorly differentiated invasive pulmonary adenocarcinoma (IPA) has a worse prognosis. Therefore, prediction of poorly differentiated IPA before treatment can provide an essential reference for therapeutic modality and personalized follow-up strategy. This study intended to train a nomogram based on CT intratumoral and peritumoral radiomics features combined with clinical semantic features, which predicted poorly differentiated IPA and was tested in independent data cohorts regarding models' generalization ability.

Discrimination of ground-glass nodular lung adenocarcinoma pathological subtypes via transfer learning: A multicenter study.

Background: The surgical approach and prognosis for invasive adenocarcinoma (IAC) and minimally invasive adenocarcinoma (MIA) of the lung differ. However, they both manifest as identical ground-glass nodules (GGNs) in computed tomography images, and no effective method exists to discriminate them.

Methods: We developed and validated a three-dimensional (3D) deep transfer learning model to discriminate IAC from MIA based on CT images of GGNs.

Preoperative prediction of tumor deposits in rectal cancer with clinical-magnetic resonance deep learning-based radiomic models.

Background: This study aimed to establish an effective model for preoperative prediction of tumor deposits (TDs) in patients with rectal cancer (RC).

Methods: In 500 patients, radiomic features were extracted from magnetic resonance imaging (MRI) using modalities such as high-resolution T2-weighted (HRT2) imaging and diffusion-weighted imaging (DWI). Machine learning (ML)-based and deep learning (DL)-based radiomic models were developed and integrated with clinical characteristics for TD prediction.

Predictive Efficacy of a Radiomics Random Forest Model for Identifying Pathological Subtypes of Lung Adenocarcinoma Presenting as Ground-Glass Nodules.

Purpose: To establish and verify the ability of a radiomics prediction model to distinguish invasive adenocarcinoma (IAC) and minimal invasive adenocarcinoma (MIA) presenting as ground-glass nodules (GGNs).

Methods: We retrospectively analyzed 118 lung GGN images and clinical data from 106 patients in our hospital from March 2016 to April 2019. All pathological classifications of lung GGN were confirmed as IAC or MIA by two pathologists.

Preoperative Monocyte-to-lymphocyte Ratio Predicts for Intravesical Recurrence in Patients With Urothelial Carcinoma of the Upper Urinary Tract After Radical Nephroureterectomy Without a History of Bladder Cancer.

Background: This study aimed to investigate the preoperative monocyte-to-lymphocyte ratio (MLR) as a biomarker for intravesical recurrence (IVR) in upper urinary tract urothelial carcinoma (UTUC) after radical nephroureterectomy (RNU) for the first time.

Patients And Methods: This study involved the clinical data of 255 patients with UTUC without a history of bladder cancer who had undergone RNU from March 2004 to February 2019 at an academic institution. The associations between MLR and IVR were assessed with Kaplan-Meier method and Cox regression analysis.

Enucleation of the Prostate for the Treatment of Benign Prostatic Hyperplasia Using a 980 nm Diode Laser.

In the aging male population, the occurrence of lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) is a common problem. Here, we introduce a new technique called 980 nm diode laser enucleation (DiLEP) to treat BPH. Diode lasers can absorb both water and hemoglobin at the same time, so they are good for cutting and hemostasis.

Diagnostic Value of Peripheral Blood miR-374b-5p in Patients with Prostate Cancer.

Background: Increased evidence suggested the important role of microRNAs (miRNAs) in the tumorigenesis of prostate cancer (PCa). The aberrant expression of miRNA (miR)-374b-5p has been observed in various types of cancers. The purpose of the current study was to evaluate the relationship between miR-374b-5p expression levels and PCa and to assess the feasibility of using peripheral blood miR-374b-5p as a potential non-invasive biomarker for PCa.

Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma.

Upper tract urothelial carcinoma (UTUC) accounts for 5%-10% of all urothelial tumors. Radical nephroureterectomy is the standard treatment procedure. At present, different choices still exist for treating the ureteral end during laparoscopic ureteral bladder sleeve resection.