Publications by authors named "Chun-Fu Chen"

Taiwan's high-tech industry is experiencing rapid labor restructuring driven by automation and technological advancement, resulting in increased job demands and workplace stress. In this context, identifying mechanisms that sustain employee performance has become a critical concern. Drawing on the concept of social capital and grounded in Conservation of Resources (COR) theory, this study investigates whether social capital indirectly enhances job performance through organizational citizenship behavior.

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Aims: To examine the level of decision difficulties of long-term-care facility (LTCF) nurses when transferring residents to the emergency department (ED) and associated influencing factors.

Design: A cross-sectional nationwide study.

Methods: The LTCFs were selected through random stratified sampling across the whole Taiwan during February 2018 to January 2019.

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Objective: The clinical characteristics of migraine with and without allodynia were compared to evaluate the risk factors of cutaneous allodynia in migraine. The effects of prophylactic therapy on allodynia in patients with migraine were assessed based on the change in pain threshold after therapy.

Patients And Methods: A total of 71 patients with migraine admitted to the Department of Neurology of Shandong Provincial Hospital were recruited in this study.

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This study investigated the effects of target distance (30, 35, and 40 cm) and the color of background lighting (red, green, blue, and yellow) on the duration of movements made by participants with low vision, myopia, and normal vision while performing a reaching task; 48 students (21 women, 27 men; M age = 21.8 year, SD = 2.4) participated in the study.

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Neovibsanins are believed to be promising candidates for the development of novel therapeutic agents to treat neurological diseases like Alzheimer's disease. It has been shown that chronic cerebral hypoperfusion is linked to neurodegenerative disorders and their subsequent cognitive impairment. In the present study effect of neovibsanin B (NVB) on spatial cognitive functions of rats with lobal cerebrovascular hypoperfusion was investigated.

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Article Synopsis
  • The study explores the prevalence of allodynia in migraine patients and the impact of pregabalin on alleviating this condition.
  • 65.1% of the 63 patients included in the study experienced allodynia, particularly more in females and those with a longer disease duration or medication overuse.
  • Pregabalin treatment led to significant reductions in allodynia symptoms and headache severity, with an overall efficiency of 85.4% and few side effects reported.
  • The research highlights a need for further exploration of central sensitization in migraine patients.
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Traditional biopsy procedures require invasive tissue removal from a living subject, followed by time-consuming and complicated processes, so noninvasive in vivo virtual biopsy, which possesses the ability to obtain exhaustive tissue images without removing tissues, is highly desired. Some sets of in vivo virtual biopsy images provided by healthy volunteers were processed by the proposed cell segmentation approach, which is based on the watershed-based approach and the concept of convergence index filter for automatic cell segmentation. Experimental results suggest that the proposed algorithm not only reveals high accuracy for cell segmentation but also has dramatic potential for noninvasive analysis of cell nuclear-to-cytoplasmic ratio (NC ratio), which is important in identifying or detecting early symptoms of diseases with abnormal NC ratios, such as skin cancers during clinical diagnosis via medical imaging analysis.

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  • The study analyzed mannitol-induced kidney impairment in patients with subarachnoid hemorrhage (SAH), focusing on differences between middle-aged and elderly patients.
  • Elderly patients experienced renal function impairment and acute renal failure sooner than middle-aged patients, indicating they have a poorer tolerance for mannitol treatment.
  • Despite the higher incidence of renal issues, there was no significant difference in mortality rates between the age groups, suggesting that age alone may not determine treatment outcomes.
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  • The study assessed the reliability and validity of the WHOQOL-BREF questionnaire among individuals with traumatic brain injury (TBI) by analyzing data from 199 participants across 22 hospitals in northern Taiwan.
  • The results showed that the questionnaire had strong internal consistency and test-retest reliability, along with general validity regarding its effectiveness in measuring quality of life related to various TBI severity indicators.
  • The findings suggest that while the WHOQOL-BREF is a suitable tool for measuring health-related quality of life in TBI patients, initial severity of the injury may not effectively predict their quality of life outcomes.
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Background: Head injury is the leading cause of death and disability for patients who experienced a major accident. It has been suggested that a well-planned neurointensive care management can effectively reduce the secondary brain insults. The BTF and the AANS proposed the Guidelines for the Management of Severe Head Injury in 1995.

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Objective: To investigate the effects of peripheral benzodiazepine receptor (PBR) in hippocampus synaptosomes on spatial learning and memory.

Methods: Twenty-four Sprague-Dawley rats of both sexes were randomly divided into 2 equal groups: D-galactose-treated group, receiving subcutaneous injection of D-galactose 100 mg/kg once a day for 56 days, and normal saline (NS) control group, receiving comparable injections of NS. Spatial learning and memory were assessed by Morris water maze test for 5 days.

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Objective: To provide information about meat consumption and factors that explain differences among subpopulations, and to evaluate how knowledge and attitudes about nutrition and awareness of diet and health influence meat consumption.

Design: The 1994-1996 Continuing Survey of Food Intakes by Individuals provided two nonconsecutive 24-hour recalls. The Diet and Health Knowledge Survey was administered at least 1 week after the last 24-hour recall.

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Objective: To confirmed reliability and feasibility of intranasal nerve growth factor (NGF) bypassing the blood-brain barrier and its potential neuroprotective effects on acute cerebral ischemia.

Methods: (1) To assay NGF concentrations in different brain regions after middle cerebral artery occlusion (MCAO). Rats were randomly divided into intranasal (i.

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