Short-term outcomes analysis of modified Karlsson procedure in chronic lateral ankle joint instability cases with generalized joint laxity.

Background: Generalized joint laxity (GJL) may affect chronic lateral ankle instability (CLAI) treatment. Short-term results of the arthroscopic-assisted modified Karlsson technique in CLAI were compared for GJL and non-GJL cases.

Methods: This retrospective analysis included 75 CLAI patients admitted to Jincheng People's Hospital from August 2019 to August 2023.

Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci.

RNA polymerase II (RNAPII) pausing in early elongation is critical for gene regulation. Paused RNAPII can be released into productive elongation by the kinase P-TEFb or targeted for premature termination by the Integrator complex. Integrator comprises endonuclease and phosphatase activities, driving termination by cleavage of nascent RNA and removal of stimulatory phosphorylation.

The Improved WNOFRFs Feature Extraction Method and Its Application to Quantitative Diagnosis for Cracked Rotor Systems.

During its operation, a rotor system can be exposed to multiple faults, such as rub-impact, misalignment, cracks and unbalancing. When a crack fault occurs on the rotor shaft, the vibration response signals contain some nonlinear components that are considerably tougher to be extracted through some linear diagnosis methods. By combining the Nonlinear Output Frequency Response Functions weighted contribution rate (WNOFRFs) and Kullback-Leibler (KL) divergence, a novel fault diagnosis method of improved WNOFRFs is proposed.

Probing Chemical Changes in Holocellulose and Lignin of Timbers in Ancient Buildings.

Wooden structures in China's ancient buildings hold highly historical and cultural values. There is an urgent need to repair and replace the damaged wooden structures after hundreds and thousands of years of exposure to weather. Unfortunately, to date there is still a lack of insightful understanding on how the chemical structure, composition, and micro-morphology evolve over the long-term natural aging before artificial ancient timbers can be developed.