Stigma and discrimination in healthcare: Challenges faced by burn patients in India.

Background: Burn injuries are a significant global public health concern, particularly in low- and- middle-income countries like India. These patients often face economic hardships, vocational limitations, and social exclusion even before sustaining their injuries. The resulting disfigurement, disability, and scarring from burns lead to increased social stigma and discrimination, exacerbating mental health concerns among survivors.

Experiences from Burn Registry Pilot Study in Northern India: Patient Profile and Implementation Perspectives.

In India, burns represent a serious public health concern due to high death and disability rates. A national burn registry was proposed under the National Program on Prevention and Management of Burn Injuries. This study reports experiences from the first pilot burn registry in India, presenting patient profiles and implementation perspectives.

Melatonin modulation of the chronic dexamethasone-induced adrenal insufficiency.

Purpose: Chronic exposure to synthetic glucocorticoids/GCs, widely in use to treat many diseases, may compromise the hypothalamic-pituitary-adrenal/HPA axis leading to a condition of adrenal insufficiency/AI. This study demonstrates the efficacy of the melatonin/MEL in amelioration of chronic dexamethasone (DEX)-induced AI.

Methods: Mice (Parkes Strain/Male/8 weeks old/30-33 g) were maintained in four groups (10 mice/group) for 30 days: Group 1/Control received intraperitoneal (i.

Genome-wide association mapping of biochemical traits and its correlation with MYMIV resistance in mungbean (Vigna radiata L. Wilczek).

The mungbean yellow mosaic India virus (MYMIV, Begomovirus vignaradiataindiaense) causes Yellow Mosaic Disease (YMD) in mungbean (Vigna radiata L.). The biochemical assays including total phenol content (TPC), total flavonoid content (TFC), ascorbic acid (AA), DPPH (2,2-diphenyl-1-picrylhydrazyl), and FRAP (Ferric Reducing Antioxidant Power) were used to study the mungbean plants defense response to MYMIV infection.

High isolated 8-port MIMO antenna and 16-port massive antenna for mm wave (5G NR-n260) applications in time division duplex mode.

In this article an 8-port annular ring-shaped MIMO antenna for 5G and 5G advanced applications is presented. An annular ring on the radiating plane and novel isolator structure on the ground plane are etched over a Rogers RT/Duorid (5870 tm) substrate to achieve high performance antenna for mm wave applications. A systematic study is performed, and an optimized single port antenna (Design-4) is selected among Designs (1-4).

An overview of deploying different treatment processes with membrane bioreactor for enhanced treatment of wastewaters: synergistic performances and reduced fouling of membrane.

The membrane bioreactor (MBR) process synergistically combines biological treatment with membrane filtration, offering a compact design and enhanced operational flexibility. However, membrane fouling remains a critical bottleneck, limiting its widespread application, particularly in treating high-strength wastewater. Recent advances have demonstrated that integrating MBR systems with auxiliary processes such as adsorption, electrochemical treatments, algal-assisted systems, and others can significantly mitigate fouling and enhance treatment efficacy.

The health workforce conundrum for burn care in Uttar Pradesh, India: a qualitative exploration.

Delivering specialised care for major burns requires a multidisciplinary health workforce. While health systems 'hardware' issues, such as shortages of the healthcare workforce and training gaps in burn care are widely acknowledged, there is limited evidence around the systems 'software' aspects, such as interest, power dynamics, and relationships that impact the healthcare workforce performance. This study explored challenges faced by the health workforce in burn care to identify issues affecting their performance.

Navigating health systems for burn care: Patient journeys and delays in Uttar Pradesh, India.

Background: India has one of the highest burden of burns. The health systems response to burn care is sometimes patchy and highly influenced by social determinants. Delay in access to acute care and rehabilitation adversely affects recovery outcomes.

Effect of Fluorine Substitution on Absorption and Emission Properties of Figure-eight-shaped [5]Helicene Dimer: A Computational Study at RI-MP2/RI-ADC(2) Level.

Chirality is a very important characteristic of optically active molecules and polyaromatics with helical structures, and plays a vital role in various applications in material science. In the present work, we show the effects of fluorine substitution at various positions in a figure-8-shaped [5]helicene dimer on the ground and excited state g-factors. Calculations for the ground and excited states are performed at the MP2 and ADC(2) levels of theory, respectively.

gene associated postprandial triglyceride dysmetabolism- a novel mechanism for diabetes risk among Asian Indians.

Aim: gene is believed to increase the risk of T2DM by its effects on insulin secretion. However, the exact mechanism of this enhanced risk is not clearly known. While gene has been shown to affect lipid metabolism, these effects have remained largely unexplored in the context of diabetes risk.

An Uncommon Presentation of Constriction Band Syndrome: A Case Report and Review of Literature.

One of the rarer manifestations of constriction band syndrome (CBS) is peripheral nerve palsy. We report a 6-year-old child presenting with motor deficits of the median, ulnar and radial nerves and atrophy of the biceps and brachialis atrophy due to CBS. We were unable to find any similar reports in the literature.

Mesoporous carbon structure impregnated with 2D engineered zirconium: A sustainable adsorbent for the removal of dyes from the aqueous solution.

The key designing of new breeds of the adsorbents aimed to improve the physical, chemical and textural morphology along with surface functionalization, selectivity toward the contaminants, and regenerations efficiency. In this aspect, two adsorbents named wet oxidative and ultrasonicated zirconium impregnated composite, have been synthesized through two routes, i.e.

Solar light-driven photocatalysis using BaFeO/rGO for chlorhexidine digluconate-contaminated water: comparison with artificial UV and visible light-mediated photocatalysis.

Synthesis and characterization of dual functioning material is an effective approach for the promotion of organic pollutant degradation through adsorption as well as photocatalysis. Herein, graphene oxide was modified by the addition of barium nitrate and iron to construct a smooth sheet-like structure (BaFeO/rGO) for the removal of chlorhexidine digluconate (CHD). Compared with GO (75.

A study of the pattern of sensory return in various flaps in different body areas.

Insensate flaps are used in several reconstructions. A search of the literature showed that most studies are limited to particular flaps in specific body areas. There is a lack of uniform scientific data on the pattern of sensory recovery in various body parts for different kinds of flaps.

Adipose Tissue Levels of DDT as Risk Factor for Obesity and Type 2 Diabetes Mellitus.

Background: Exposure to dichlorodiphenyltrichloroethane (DDT), a potent lipophilic organochlorine pesticide, has long been linked as a risk factor for type 2 diabetes mellitus (T2DM). However, its presence in the adipose tissues of the T2DM subjects has not been explored in the Indian population, where this long-banned pesticide is still in use. The present study was conducted to evaluate the possible association of DDT and its metabolites in obese and non-obese T2DM subjects.

COVID-19 associated mucormycosis: Staging and management recommendations (Report of a multi-disciplinary expert committee).

Even before the onslaught of COVID-19 pandemic could settle, the unprecedented rise in cases with COVID-19 associated mucormycosis pushed the medical health to the fringe. Hyperglycaemia and corticosteroids appear to be the most consistent associations leading to the commonest manifestation of mucormycosis, Rhino-Orbito-Cerebral Mucormycosis. To address challenges right from categorisation and staging of the disease to the management of relentless progression, a multi-disciplinary expert committee was formed to handle the task in an evidence-based format to enforce best practices.

Mesenchymal Stromal Cell-Derived Tailored Exosomes Treat Bacteria-Associated Diabetes Foot Ulcers: A Customized Approach From Bench to Bed.

Exosomes are nano-vesicles of endosomal origin inherited with characteristics of drug delivery and cargo loading. Exosomes offer a diverse range of opportunities that can be exploited in the treatment of various diseases post-functionalization. This membrane engineering is recently being used in the management of bacteria-associated diabetic foot ulcers (DFUs).

Evaluation of Role of Arterialization of Venous Flaps in Abdomen in Rats.

 Reconstruction forms the primary tenet in plastic surgery. Venous flaps are a known option but the survival is limited. Arterialization of venous flap can enhance its survival.

Mesenchymal Stem Cell-Derived Exosomes Exhibit Promising Potential for Treating SARS-CoV-2-Infected Patients.

The novel coronavirus severe acute respiratory syndrome-CoV-2 (SARS-CoV-2) is responsible for COVID-19 infection. The COVID-19 pandemic represents one of the worst global threats in the 21st century since World War II. This pandemic has led to a worldwide economic recession and crisis due to lockdown.

Understanding the toxicity effect and mineralization efficiency of in-situ electrogenerated chlorine dioxide for the treatment of priority pollutants of coking wastewater.

Oxidation of phenol, cyanide and aniline have been analyzed by the enhanced electro-oxidation process in which sodium chlorite was used as an electrolyte and results were validated using statistical tool based on Box-Behnken design. The mineralization efficiency of 78.4%, and 98.

A systematic review and comprehensive legislative framework to address chemical assault globally.

The incidence of chemical assault is increasing globally. In response, a number of countries are proposing legislation. However, current legislative initiatives are uncoordinated and do not address the spectrum of activities to prevent and care for victims of chemical assaults.

Level of Organochlorine Pesticide in Prediabetic and Newly Diagnosed Diabetes Mellitus Patients with Varying Degree of Glucose Intolerance and Insulin Resistance among North Indian Population.

Background: Organochlorine pesticides (OCPs) exposure may induce an endocrine disruption which may lead to the risk of developing diabetes through alteration and disturbance of glucose metabolism, insulin resistance, and destruction of β-cells. The present study determines the recent trend of OCPs residue in blood samples and their association with the known risk factors responsible for developing the risk of diabetes among the North Indian population.

Methods: Blood sample of 300 patients (100 each of normal glucose tolerance [NGT], prediabetes and newly detected diabetes mellitus [DM]) between the age group of 30 to 70 years were collected.

High levels of organochlorine pesticides in drinking water as a risk factor for type 2 diabetes: A study in north India.

Organochlorine pesticides (OCPs) are well known synthetic pesticides widely used in agricultural practices and public health program. Higher toxicity, slow degradation, and bioaccumulation are the significant challenges of OCPs. Due to its uses in agricultural and public health, contamination of drinking water and water table also increases day by day.