Survival predictors of lung cancer patients in ICU: the importance of acute kidney injury prediction and prevention.

Background: To identify potential predictors of short-term survival among patients with lung cancer admitted to the intensive care unit (ICU).

Methods: A multicenter longitudinal observational study of patients with lung cancer was conducted between May 10, 2021 and July 10, 2021, at the ICUs of 37 cancer-specialty hospitals in China. This study included patients with a primary diagnosis of lung cancer who were admitted to the ICU for ≥24 h.

Two cross-neutralizing antibodies isolated from a COVID-19 convalescent via single B cell sorting.

The ongoing emergence of Omicron subvariants, which exhibit significant resistance to existing therapeutic antibodies, underscores the urgent need to develop new reagents capable of broadly and effectively neutralizing current subvariants. Antigen-specific memory B cells were sorted by flow cytometry. The heavy and light variable region genes of monoclonal antibodies (mAbs) were amplified and cloned into expression vectors.

Intensive care unit outcomes and prognostic factors of esophageal cancer: A cross-sectional study in Chinese cancer-specialized hospitals.

Background: Esophageal cancer patients had the highest intensive care unit (ICU) admitted rate in cancer patients. But their prognosis and evaluation methods were rarely studied.

Aim: To depict the short-term mortality outcome and identify the potential prognostic factors of esophageal cancer patients admitted into ICU.

De Novo Synthesis of Oligofurans via Copper-Catalyzed Dimerization of Ethynylethylene Carbonates.

Disclosed here is an efficient Cu-catalyzed de novo synthesis of oligofurans, a type of valuable core unit in organic materials. From the readily available ethynylethylene carbonates, the dimerization process allowed convenient access to differently substituted oligofurans that could not have been easily synthesized before. In contrast to the conventional strategies, this protocol does not rely on preinstallation of cross-coupling functionalities or presynthesis of advanced enyne precursors.

Near-Infrared Spectroscopy and Machine Learning for Fast Quality Prediction of Bottle Gourd.

Protein and amino acid content are the crucial quality parameters in bottle gourd, and traditional measurement methods for detecting those parameters are complicated, time-consuming, and costly. In this study, we employed NIRS along with machine learning and neural network-based methods to model and predict protein and free amino acids (FAAs) of bottle gourd. Specifically, the content of protein and FAAs were measured through conventional methods.

Exploring the role of social media in mathematics learning: effects on self-efficacy, interest, and self-regulation.

Background: Social media's integration into education prompts exploration of its effects on mathematics learning outcomes. While Mathematics Learning with Social Media (MLSM) can create engaging environments, its impact on key factors such as mathematics self-efficacy (MathSE), mathematics interest (MathI), and self-regulation in mathematics learning (SR) remains underexplored. This study investigates the direct and indirect effects of MLSM on these variables to enhance mathematics education.

Responses of Subsoil Organic Carbon to Climate Warming and Cooling Is Determined by Microbial Community Rather Than Its Molecular Composition.

Little is currently known about how long-term climate changes modulate the relationship between soil organic carbon (SOC) molecular composition, microbial community and SOC storage and the mechanisms involved. Here, we show substantial changes in subsoil SOC in the Qinghai-Tibetan alpine grasslands over 16 years of soil warming and cooling. Warming reduced SOC content by 8.

Soil transplantation: complex interplay between soil microbes and the local environment.

Soil transplantation, the introduction of co-adapted soil microbes to maintain plant-microbe interactions in novel environments, is increasingly used to mitigate climate change effects on plants. However, it yields variable outcomes. We performed a reciprocal transplantation experiment at three elevations, plus a glasshouse experiment, where seedlings of three species were grown in rhizosphere soils from conspecific individuals collected from their original (home soil) or transplanted (away soil) sites.

A multicentre, randomised controlled clinical trial evaluating the effect of the adsorptive filter oXiris on haemodynamics in abdominal septic shock patients requiring continuous renal replacement therapy (Oxiris for Abdominal SEptic Shock study).

Introduction: Septic shock-associated acute kidney injury (AKI) is known to carry a poor prognosis. The present study aims to evaluate the effect of absorptive blood purification on haemodynamic status and clinical outcomes in patients with septic shock-associated AKI.

Methods And Analysis: This multicentre, randomised controlled trial will evaluate an adsorbent filter (oXiris) in patients with abdominal septic shock requiring continuous renal replacement therapy (CRRT).

Jasmonic acid-mediated cell wall biosynthesis pathway involved in pepper (Capsicum annuum) defense response to Ralstonia solanacearum.

Ralstonia solanacearum is a destructive soil-borne pathogen that causes severe bacterial wilt (BW) disease in peppers. Phytohormone signaling pathways, including those mediated by jasmonic acid (JA), are crucial to plant defense responses against pathogen attacks. Nevertheless, the function of JA in the resistance response of pepper to R.

Cobalt-Catalyzed Reduction of Propargyl Alcohols for the Synthesis of 1,3-Diarylallenes Under N,N-Ligand and Hydride-free Conditions.

Allenes are a class of important organic compounds, and their synthesis has always been of great interest. In this article, we have developed a cobalt-catalyzed photoredox strategy, providing an alternative and efficient approach for the synthesis of 1,3-diarylallenes from propargyl alcohols. The reaction utilized organic amines as a hydrogen source to avoid the use of conventional hydride additives and does not require the addition of extra N,N-ligands to activate the cobalt catalyst, achieving a mild reaction condition.

Unraveling the links between molecular weight and multidimensional dynamics of dissolved organic matter in the runoff from gentle sloping land under rainfall.

Molecular weight is a fundamental intrinsic property of dissolved organic matter (DOM), playing a crucial role in its bio-stability, microbial transformation, and contributions to regional carbon cycling. However, the complex relationships between the molecular weight and multidimensional dynamics of DOM in the runoff remain insufficiently understood. In this study, fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) was employed to elucidate the associations between molecular weight and multidimensional dynamics of DOM in surface runoff and subsurface runoff from gentle sloping land (i.

Mycorrhizal symbioses and tree diversity in global forest communities.

Unraveling the mechanisms underlying the maintenance of species diversity is a central pursuit in ecology. It has been hypothesized that ectomycorrhizal (EcM) in contrast to arbuscular mycorrhizal fungi can reduce tree species diversity in local communities, which remains to be tested at the global scale. To address this gap, we analyzed global forest inventory data and revealed that the relationship between tree species richness and EcM tree proportion varied along environmental gradients.

Arbuscular mycorrhizal fungi enhance nitrogen acquisition from, but not carbon loss of, organic matter in soil.

The effect of arbuscular mycorrhizal fungi (AMF) on decomposition can be regulated by their role in plant nitrogen acquisition due to their obligate biotrophic lifestyle. However, few studies have addressed the relationship between these two processes. We conducted an experiment using mycorrhizal-defective mutants and wild-types of two plant species with C and N dual-labelled litter as tracers.

Morphological characters and molecular data reveal ten new forest macrofungi species from Hebei Province, North China.

China has a complex and diverse forest ecological environment, which breeds abundant forest macrofungi, including some edible, medicinal, and poisonous species. During the investigations of macrofungi in the Saihanba National Nature Reserve, North China, we collected abundant specimens of Agaricales and Polyporales within the Agaricomycetes. Based on the morphological characters and molecular evidence of DNA sequences including the internal transcribed spacer (ITS) regions, the large subunit of nuclear ribosomal RNA gene (nLSU), the small subunit of mitochondrial rRNA gene (mtSSU), the small subunit of nuclear ribosomal RNA gene (nuSSU), the largest subunit of RNA polymerase II (RPB1), the second largest subunit of RNA polymerase II gene (RPB2), the β-tubulin gene (TUB), and the translation elongation factor 1-α gene (TEF1), this study identifies ten species of Agaricales and Polyporales new to science, viz.

Native Plant Diversity Provides Resistance to Invasion by an Alien Species in Natural and Experimental Settings.

It remains uncertain whether native plant diversity increases resistance to plant invasions at meaningful scales in nature due to contradictions between observational and experimental studies. In a field survey of 253 sites spanning 15 latitudinal degrees in China, we found that the relative abundance of the invader Alternanthera philoxeroides decreased with increasing native plant richness. Results from a 3-year field experiment and a 2-year mesocosm experiment further demonstrated that native diversity can suppress A.

[Ecological stoichiometric imbalance drives the responses of soil bacterial communities to nitrogen addition in an alpine meadow].

Nitrogen is the main limiting nutrient for the productivity of grassland ecosystems, and can indirectly affect the structure of microbial communities, especially bacterial communities, by altering soil properties. In this study, we conducted a field nitrogen addition experiment in the alpine meadow of Haibei in the northeastern Tibetan Plateau. Urea was used as the nitrogen source.

Global patterns of nutrient limitation in soil microorganisms.

The availability of nitrogen (N) and phosphorus (P) is essential for soil microbial activity and growth, yet global patterns of N and P limitation in soil microbial metabolism remain largely unknown. We modeled ecoenzyme stoichiometry data from 5,259 field observations of natural ecosystems to assess microbial N and P limitation in global surface soils. We found that microbial P limitation, which was especially strong at low latitudes, was more prevalent globally than microbial N limitation, which prevailed in cold environments.

Knowledge, Attitude, and Practice of Palliative Care Among Physicians and Nurses in Intensive Care Units in Shanghai, China.

Purpose: The growing need for palliative care in China's aging population highlights the intensive care unit (ICU) staff's crucial role and need for specialized training and improved knowledge, attitude, and practice (KAP). The study aims to assess the KAP of palliative care ICU physicians and nurses and identify influencing factors.

Patients And Methods: A cross-sectional survey was conducted among ICU physicians and nurses at three Shanghai hospitals.

Microbial Immobilization Shapes the Non-Linear Response of Allochthonous Nitrogen Retention to Grassland Acidification Within Soil Aggregates.

Soil nitrogen (N) retention plays a crucial role in determining the ecosystem capacity to buffer anthropogenic N inputs and provides a sustainable N supply. However, the effect of acidification, driven by atmospheric deposition of N and sulfur (S), on the retention and fate of allochthonous N across soil aggregate size classes remains poorly understood. We utilized a soil-acidification gradient induced by 0-50 g S m year addition to investigate N recovery in soil N pools within aggregates 21 days after labeling in a Eurasian meadow.

A Case of Pulmonary Infection Caused by in an AIDS Patient and Literature Review.

is a rare opportunistic Gram-positive bacterium that primarily affects immunocompromised individuals, particularly those with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). The infection often presents as a multisystem, disseminated disease with rapid progression and high mortality if not promptly diagnosed and treated. We report the case of a 34-year-old male AIDS patient who developed pulmonary infection due to .

Tunable asymmetric Mach-Zehnder interferometer based on spoof surface plasmon polaritons.

In this paper, an ultrathin asymmetric Mach-Zehnder interferometer (MZI) based on spoof surface plasmon polaritons (SSPPs) is proposed. The asymmetry in the MZI structure induces a phase difference between the SSPPs waves propagating in the upper and lower arms of the device, leading to interference valleys in the output signal. Additionally, by loading two varactor diodes on the lower arm of the MZI, the position of the interference valleys can be manipulated by varying the bias voltage on the diodes.

Decoupling Responses of Phyllosphere and Rhizosphere Bacterial Communities to Spatiotemporal Environmental Changes.

Understanding and predicting how plant-associated microbes respond to environmental changes is of key importance to understanding future plant performance. Yet, how aboveground and belowground plant-associated microbial communities, which may interactively affect plant performance, simultaneously respond to environmental changes, remains unknown. To fill this gap, we monitored temporal changes of phyllosphere and rhizosphere bacterial communities of three perennial species at 18 sites spanning a 1500 m elevational gradient.

CaMYBA-CaMYC-CaTTG1 complex activates the transcription of anthocyanin synthesis structural genes and regulates anthocyanin accumulation in pepper ( L.) leaves.

Anthocyanins are flavonoid-derived metabolites that contribute to plant and human health. At present, few studies have studied the biosynthesis and accumulation mechanism of anthocyanins in pepper leaves. The role of CaMYBA-CaMYC-CaTTG1 complex in anthocyanin biosynthesis in pepper leaves was studied.