Dental Pulp Calcification Among Young Cancer Survivors: A Cross-Sectional Exploratory Study.

Several studies have evaluated the effects of cancer-related chemo-radiation on developing teeth, leading to disturbances in the formation of enamel and dentin, affecting the crown and root. However, their impact on dental pulp has not been well explored. The purpose of this study was to evaluate dental pulp calcification among young cancer survivors.

Flexible Splinting: A Minimally Invasive Approach to Managing a Pediatric Mandibular Fracture With Traumatic Bone Loss.

Pediatric mandibular fractures necessitate a specialized treatment approach due to the complexities of craniofacial development, dentition, and active bony growth centers. This case report describes the management of an eight-year-old boy who sustained a mandibular fracture with the traumatic loss of a triangular bone fragment following a fall. Clinical and radiographic evaluation confirmed a compound comminuted fracture of the mandibular body.

Knowledge, attitudes and practices of orthodontists regarding orthodontic treatment of traumatized teeth: a systematic review.

Purpose: To assess the global status of the knowledge, attitudes, and practices of orthodontists regarding the orthodontic treatment of traumatized teeth.

Methods: An a priori protocol was developed and registered (PROSPERO, CRD42022342038). The literature search based on the Population, Intervention, Comparator, and Outcome (PICO) elements of the research question was developed and conducted electronically in PubMed, LILACS, Web of Science, EMBASE, Scopus, and the Cochrane Library, up to 31st August 2024.

Trauma-Induced Stress Distribution in Primary Incisors Restored With Preformed Zirconia Crowns: 3D Finite Element Analysis.

Background/aims: Preformed zirconia crowns have emerged as the preferred choice for restoring damaged primary incisors. However, they differ from natural teeth in their biophysical properties and can potentially alter the overall response of crowned teeth to a traumatic load. This in silico study aimed to compare the response of three different traumatic loading conditions for the (i) natural (M1) and (ii) zirconia-restored tooth models (M2) models.

Effect of temperature on rehydration and fracture resistance of reattached tooth fragments after crown fracture: An in vitro study.

Background: Uncomplicated crown fractures of maxillary anterior teeth are common dental injuries, and the bonding of fractured fragments is recommended for management. Rehydration of fragments improves bonding and fracture resistance. Therefore, the aim of this study was to compare the fracture resistance of the reattached tooth fragment of the incisor crown after rehydration using either a steamer or a humidifier.

First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of BMS-986308: A Renal Outer Medullary Potassium Channel Inhibitor.

In patients with heart failure (HF) who respond inadequately to loop diuretic therapy, BMS-986308, an oral, selective, reversible renal outer medullary potassium channel (ROMK) inhibitor may represent an effective diuretic with a novel mechanism of action. We present data from the first-in-human study aimed to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) following single ascending doses of BMS-986308 in healthy adult participants. Forty healthy participants, aged from 20 to 55 years, and body mass index (BMI) from 19.

Isolation and detection of bacterial species on mitis salivarius bacitracin agar from the plaque samples of caries active children.

Background: In cariology studies, mitis-salivarius-bacitracin (MSB) agar has been commonly considered as the selective medium for Streptococcusmutans growth. The present study was the part of a funded project (a noninferiority randomized controlled trial) which compared the efficacy of a plant extract-based mouth rinse with that of a fluoride mouth rinse on the S.mutans counts of the children.

The risk of bonded fragment loss in crown-fractured anterior teeth managed by fragment reattachment: a systematic review and meta-analysis.

Purpose: To identify the factors affecting the risk of bonded fragment loss in crown-fractured anterior teeth managed by fragment reattachment.

Methods: The study protocol followed the best practices of evidence-based medicine and was registered in PROSPERO. A comprehensive literature search was performed electronically in six databases (PubMed, Embase, SCOPUS, Web-of-Science, Lilacs, and Cochrane) on 18-09-2023.

Risk of pulp necrosis and related complications in the permanent anterior teeth with lateral luxation: A systematic review and meta-analysis.

This systematic review aimed to evaluate the evidence related to the occurrence of pulp necrosis and related complications in permanent anterior teeth with lateral luxation. It was envisaged to address the ambiguity related to the recommendation for pulp extirpation in teeth with mature root apex. An a priori protocol was formulated as per the best practices of evidence-based medicine and registered in PROSPERO.

Methods and applications of finite element analysis in dental trauma research: A scoping review.

Finite Element Analysis (FEA) is vital for understanding dental traumatology (DT) biomechanics, aiding diagnosis, treatment planning, and outcome prediction. This review explores FEA applications in DT research, evaluates their quality and outcomes, and assesses methodological aspects. Accordingly, recommendations for future researchers are provided.

Effect of wire diameter and extent of wire composite splint on the mobility of luxated and anchor primary teeth: A typodont study.

Background/aims: The recommendations for splinting are well established for the injuries of permanent dentition; however, ambiguity still exists for the injuries in primary dentition. Hence, this study aimed to determine the most appropriate dimensions of stainless steel wire and its extent, for achieving the physiologic mobility in primary dentition.

Material And Methods: This study was designed as an in vitro experiment by using a typodont model of primary dentition.

Effect of 940 nm diode laser irradiation and dentin bonding agent on permeability of furcation area in primary molars.

Purpose: Multiple accessory canals make furcation area of primary molars the most common port of entry of bacterial endotoxins to periradicular area. Reduction in permeability can improve prognosis of these teeth. Therefore, this study was designed to compare the effect of 940 nm diode laser and dentin bonding agent on the dye penetration of furcation area in primary molars.

Effectiveness of various methods of educating children and adolescents for the maintenance of oral health: A systematic review of randomized controlled trials.

Background: School-based oral health education has emerged as one of the most effective methods to instill a positive attitude toward oral health in children.

Aim: This systematic review (SR) aimed to assess the effectiveness of different methods of oral health education in children and adolescents.

Design: Systematic search was conducted in PubMed, Cochrane, Web of Science, LILACS, Scopus, and EMBASE on January 29, 2023.

Comparative assessment of scientific reach and utilization of the International Association of Dental Traumatology 2020 guidelines: An altmetric and citation analysis.

Background/aim: The updated version of the International Association of Dental Traumatology (IADT) guidelines was published online in May 2020 in the form of four papers. They are extensively used in dental trauma education in textbooks, undergraduate and postgraduate programs, and clinical workshops. Hence, this study aimed to assess the impact, global scientific reach, and utilization of these guidelines through altmetric and citation analysis.

Comparative evaluation of three materials used for fragment reattachment in uncomplicated crown fracture-An in vitro study using bovine teeth.

Background/aims: The recommended treatment for uncomplicated crown fractures is bonding the fractured fragment or the fragment reattachment. A paucity was identified regarding the studies comparing the efficacy of micro-hybrid and nanohybrid composites in fragment reattachment. Hence, the present study aimed to evaluate and compare three materials for bonding of fragments rehydrated by humidification in teeth with uncomplicated crown fractures.

Essentially entropic lattice Boltzmann model: Theory and simulations.

We present a detailed description of the essentially entropic lattice Boltzmann model. The entropic lattice Boltzmann model guarantees unconditional numerical stability by iteratively solving the nonlinear entropy evolution equation. In this paper we explain the construction of closed-form analytic solutions to this equation.

Development and validation of risk of bias tool for the use of finite element analysis in dentistry (ROBFEAD).

There has been a systematic review of studies that used FEA in dental sciences, but no adequate risk of bias (RoB) analysis technique has been developed. Therefore, the development and validation process of RoB in studies using the finite element analysis in dentistry (ROBFEAD) tool is described. In the first phase of development, the scope of the tool and possible modifications were covered, and validation was done in the second phase.

In-vitro Evaluation for Effects of Intracanal Medicaments on Viability, Proliferation, and Differentiation of Stem Cells From Apical Papilla - A Systematic Review.

This systematic review aimed to evaluate the cytotoxicity of intracanal medicaments used for root canal disinfection and assess their effect on the proliferation and differentiation potential of stem cells from apical papilla (SCAP). The PubMed/Medline, Cochrane, Scopus, EMBASE, CINAHL and Web of Science databases were searched. Studies evaluating the effect of intracanal medicament on human SCAP (in-vitro primary cell culture experiment) were included in this systematic review.

Long-term effects of chemotherapy and radiation received during early childhood on the developing dentition of pediatric cancer patients.

Introduction: The short-term effects of chemotherapy and irradiation are well documented; however, there is paucity regarding their long-term effects, especially in children and adolescents.

Case Description: This paper discusses the long-term effects of chemotherapy and/or radiation received by the patients during their early childhood on the developing dentition. It comprises the compilation of 11 cases with alteration in the dental development screened from 138 cases of the childhood cancer patients who received the chemotherapy and/or radiation as a part of anticancer therapy.

Reporting guidelines for in-silico studies using finite element analysis in medicine (RIFEM).

Background: To the best of our knowledge, there are no reporting guidelines for design, conduct and reporting of Finite Element studies in health sciences. We intend to propose specific and detailed guidelines for reporting these studies.

Method: After recognizing the need to have uniform guidelines for reporting of finite element analysis in medicine and dentistry, a group of 5 researchers working on FEA as their research area met in the summer of 2020 and drafted the methodology for the development of such guidelines.

SARS-CoV-2 Reinfection Rate and Estimated Effectiveness of the Inactivated Whole Virion Vaccine BBV152 Against Reinfection Among Health Care Workers in New Delhi, India.

Importance: A surge of COVID-19 occurred from March to June 2021, in New Delhi, India, linked to the B.1.617.