Protocol of a randomized controlled multicenter trial investigating process and effectiveness of a participatory organizational approach for preventing work-related mental health problems among employees: vital@work.

Background: Evidence links psychosocial work factors to work-related mental health problems, which affect productivity and highlight the need for workplace interventions. In order to establish sustainable change, a participatory strategy that considers the behavioral, organizational, and contextual (BOC) determinants when selecting and implementing interventions is needed. The objective of the current study, Vital@Work, is to prevent and reduce work-related mental health problems by using an evidence based Participatory Approach (PA) as strategy to compose a set of intervention activities tailored to BOC determinants.

Temporal dynamics of perceived self-reliance and psychiatric symptoms in older adults: applying dynamic time warping to longitudinal cohort data.

Objectives: Contemporary public health and care policies expect that promoting self-reliance can help older adults prevent or recover from morbidity, including psychiatric disorders. We sought to clarify the role of self-reliance dynamics in developing and recovering from psychiatric symptoms throughout the aging process.

Method: We used dynamic time warping to analyze the temporal ordering of within-person changes in five self-reliance indicators (three self-efficacy dimensions, mastery, self-esteem) and psychiatric symptoms in  = 1968 participants aged 55+ in the Longitudinal Aging Study Amsterdam, measured up to ten times across up to 30 years.

Bias by gender: exploring gender-based differences in the endorsement of ADHD symptoms and impairment among adult patients.

Background: Research on adult attention-deficit/hyperactivity disorder (ADHD) remains limited, particularly regarding the experiences of women.

Methods: This exploratory study investigates patient responses to the Diagnostic Interview for ADHD in Adults (DIVA-5), which assesses current (adult) and retrospective (childhood) ADHD symptoms based on criteria from the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). We focused on overall endorsement rates of ADHD symptoms, impairments, and specific examples of both, with particular attention to gender differences.

Confusional States During Electroconvulsive Therapy for Late-Life Depression: A Prospective Cohort Study.

Introduction: Cognitive side effects, such as memory loss, associated with electroconvulsive therapy (ECT) have been extensively studied. However, knowledge about (sub)acute confusional states during ECT is limited, particularly in older adults with depression. Their incidence, recurrence, and co-occurrence remain unclear.

Needs of the network: a qualitative study of the needs of family members, partners and close friends of people with a severe mental illness (SMI).

Background: Mental healthcare for people with a severe mental illness (SMI) is increasingly being delivered in a deinstitutionalized setting. Community-dwelling, ambulatory care and support, and the associated treatment goals have implications for the roles and experiences of family members and close friends of people with an SMI. This study aims to provide a deeper understanding of what social network members of people with an SMI need to cope with the effects of the illness and possible caregiving responsibilities and remain involved.

Eye Movement Desensitization and Reprocessing with and without Dialectical Behavior Therapy for Posttraumatic Stress Disorder and Comorbid Borderline Personality Disorder Symptoms: A Randomized Controlled Trial.

Introduction: Comorbidity between posttraumatic stress disorder (PTSD) and borderline personality disorder (BPD) is prevalent. Despite evidence-based therapies, high rates of nonresponse and dropout persist. This study therefore aimed to examine whether the concurrent application of eye movement desensitization and reprocessing (EMDR) for PTSD and dialectical behavior therapy (DBT) for BPD yields better results than EMDR alone.

Associations Between Epistemic Trust and the Severity of Personality Disorder: Results From a Study Comparing Patients With Personality Disorder, Anxiety Disorder, and Controls.

Early childhood adversity may dispose an individual to adopt a rigid and pervasive hypervigilant position toward information coming from others, resulting in high levels of epistemic mistrust (EM), which is supposed to increase the risk of developing psychopathology. A more intrinsic relationship between EM and the development of personality disorders (PDs) is assumed. Although the theory of epistemic trust (ET) is rather novel, it has quickly become widely accepted in the field, despite much empirical evidence.

Empathy and Mentalizing of Mental Health Nurses: A Cross-Sectional Correlational Study.

In mental healthcare, therapists' empathy and mentalizing are associated with better opportunities to establish positive working relations with patients. The present study aimed to explore mental health nurses' level of empathy and mentalizing (compared with reference groups studying or working in different contexts), the association between mental health nurses' level of empathy and mentalizing and sociodemographic characteristics of these nurses, and the association between mental health nurses' level of empathy and mentalizing. A cross-sectional design was used in adherence with the Strengthening the Reporting of Observational Studies in Epidemiology statement.

Associations between Childhood Trauma and Epistemic Trust, Attachment, Mentalizing, and Symptoms of Borderline Personality Disorder.

Introduction: The construct of epistemic trust (ET) has gained wide acceptance and support in the field, although there is little empirical evidence to substantiate the theoretical assumed model. Studies of the assessment of ET were conducted in community samples only and the mediating role of attachment and mentalizing in addition to ET was not investigated. This study examines the theoretical assumed relationships between ET and attachment and mentalizing as well as the mediating role of attachment, mentalizing and ET in the association between childhood adversity and borderline personality disorder (BPD) in a heterogeneous sample containing also patients.

Affective Aspects of Religiousness and 6-Year Course of Depressive Symptoms in Aged Dutch Citizens.

In prospective studies on religiousness and depressive symptoms, it remains unclear whether religiousness is a predictor or parallels the fluctuating course of depressive symptoms. The current study focuses on several affective aspects of religiousness in their associations over time with late life depressive symptoms. As part of the population-based Longitudinal Aging Study Amsterdam, a subsample of 222 respondents (mean age 76.

The D*Phase-study: Comparing short-term psychodynamic psychotherapy and cognitive behavioural therapy for major depressive disorder in a randomised controlled non-inferiority trial.

Background: Given both the large volume and manifold preferences of patients with depression, the availability of various effective treatments is important. Psychodynamic psychotherapy (PDT) has received less research in comparison to cognitive behavioural therapy (CBT) for major depressive disorder (MDD). This study aimed to establish whether short-term psychodynamic supportive psychotherapy (SPSP) is non-inferior to CBT in the treatment of MDD.

Running therapy or antidepressants as treatments for immunometabolic depression in patients with depressive and anxiety disorders: A secondary analysis of the MOTAR study.

Background: Exercise promotes immunometabolic health and is increasingly recognized as an effective depression treatment. Exercise may be beneficial for patients with immunometabolic depression (IMD), who experience inflammatory and metabolic dysregulations and may respond less to antidepressants. This secondary analysis of the MOTAR study compared the effects of running therapy and antidepressants on IMD features among patients with depression and/or anxiety disorder.

Effects of Chronotherapeutic Interventions in Adults With ADHD and Delayed Sleep Phase Syndrome (DSPS) on Regulation of Appetite and Glucose Metabolism.

ADHD is highly comorbid with Delayed Sleep Phase Syndrome (DSPS). Both are associated with obesity and diabetes, which can be caused by long-term dysregulations of appetite and glucose metabolism. This study explores hormones involved in these processes and the effects of chronotherapeutic interventions in a small sample of adults with ADHD and DSPS.

Discontinuity of psychiatric care among patients with bipolar disorder in the Netherlands.

Background: Patients with bipolar disorder benefit from guidelines recommended continuous community-oriented psychiatric and somatic healthcare, but often discontinue psychiatric care.

Aims: The first objective was to identify predictive factors of discontinuity of psychiatric care among patients who had received psychiatric care. The second objective was to examine if practice variation in discontinuity of psychiatric care existed between providers of psychiatric care.

Predictors of treatment attendance in patients with posttraumatic stress disorder and comorbid personality disorders.

Introduction: High dropout and low treatment attendance rates among patients with posttraumatic stress disorder (PTSD) and personality disorders (PDs) continue to pose a significant challenge. Despite numerous studies focusing on enhancing treatment attendance, the identification of consistent and reliable predictors in patients with PTSD and comorbid PDs remains limited.

Objectives: This study aims to investigate a wide range of potential predictors of treatment attendance, encompassing demographic, patient-severity, treatment, and therapist-related variables in patients with PTSD and comorbid borderline and/or cluster C PDs.

A network perspective on posttraumatic stress disorder and comorbid borderline personality disorder symptoms.

Comorbidity between posttraumatic stress disorder (PTSD) and borderline personality disorder (BPD) is surrounded by diagnostic controversy and although various effective treatments exist, dropout and nonresponse are high. By estimating the network structure of comorbid PTSD and BPD symptoms, the current study illustrates how the network perspective offers tools to tackle these challenges. The sample comprised of 154 patients with a PTSD diagnosis and BPD symptoms, assessed by clinician-administered interviews.

Recovery of adults with autism spectrum disorder during intensive inpatient treatment: a qualitative study.

Introduction: Although some adults with autism spectrum disorder (ASD) require intensive and specialized ASD treatment, there is little research on how these adults experience the recovery process. Recovery is defined as the significant improvement in general functioning compared to the situation prior to treatment.

Methods: This qualitative study describes the recovery process from the perspective of adults on the autism spectrum during intensive inpatient treatment.