Functional Outcomes in Failed Osteosynthesis of Proximal Femoral Fractures Managed by Total Hip Replacement Using the Modified Hardinge Approach: An Ambispective Cohort Study.

Introduction Proximal femoral fractures are a major cause of disability, particularly in aging populations, with an increasing incidence. Although osteosynthesis remains the first-line treatment, failures are common due to various complications. Total hip arthroplasty (THA) is the preferred salvage procedure in such cases, despite its technical challenges.

An Approach to Drug Discovery via Ethnopharmacology and Sustainable Agriculture.

Ethnopharmacology is the study of traditional medicinal knowledge and its application in modern drug discovery. It combines ethnobotanical insights with scientific research to identify bio-active compounds with therapeutic potential. Sustainable agriculture refers to farming practices that maintain ecological balance, support biodiversity, and ensure the long-term availability of resources.

From Growth to Survival: Aux/IAA Genes in Plant Development and Stress Management.

Auxin, one of the earliest recognized and extensively investigated phytohormones, is crucial in plant growth and survival in adverse environmental conditions. Two gene families primarily regulate auxin signaling: auxin response factors (ARFs) and auxin/indole-3-acetic acid (Aux/IAA). Aux/IAA family proteins are recognized as essential elements of the nuclear auxin signaling system, inhibiting gene transcription in their presence and facilitating gene activation upon their degradation.

Exploration of the Chemical Components and Biological Activities of Hippophae salicifolia Extracts: In Vitro, Molecular Docking, and MD Simulation Approaches.

Hippophae salicifolia, commonly known as sea buckthorn, is native to the Indian Himalayan region. This study is the first to comprehensively assess the phytochemical profile and biological activities of H. salicifolia leaves extracted through maceration, infusion, and percolation (Soxhlet apparatus) methods.

Assessing the Communication Skills, Self-efficacy, and Mindfulness in Nurses Working in Children's Healthcare Units: A Cross-sectional Approach.

Introduction: Effective communication, self-efficacy, and mindfulness are critical for nurses working in children's healthcare units. These competencies impact patient care quality and the nurses' professional confidence and well-being. The aim of the study was to assess communication skills, self-efficacy, and mindfulness levels among nurses and explore their interrelationships and associated factors.