Publications by authors named "Saritha"

Coating fabrics with natural rubber latex (NRL) dispersions containing various nanofillers offers a versatile approach for developing multifunctional fabrics. In this study, polyester/cotton blended fabrics were coated with NRL by incorporating 3 phr (parts per hundred rubber) of molybdenum disulfide-tannic acid dispersion (MT) and 7 phr of lignin nanoparticles (LNP) using a dipping method. Two types of coated fabric samples were prepared: single-cycle and double-cycle coated fabrics.

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Metal-organic frameworks (MOFs) are a novel class of porous materials that combine organic linkers and inorganic metal ions. Supercapacitors use a large specific surface area, adjustable architecture, and tunable porosity and pore diameters to improve the electrochemical performances with metal sulfides. The main goal of this study was to make a nickel oxide ternary composite using a hydrothermal method with urea as a catalyst for electrochemical uses.

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The potential of two-dimensional (2D) transition metal dichalcogenides (TMDs), especially molybdenum telluride (MoTe), in sophisticated electrical and low-energy neuromorphic applications, has attracted a lot of interest. The creation, characteristics, and uses of MoTe-based memristive devices are summarized in this review paper, with an emphasis on their potential as artificial synapses for neuromorphic computing. We thoroughly examine the special properties of MoTe, such as its remarkable resistance switching response, excellent linearity in synaptic potentiation, and customizable phase states.

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Lymphatic filariasis (LF) stands as a debilitating tropical ailment, impacting a considerable global populace. Existing drug therapies for LF exhibit limited effectiveness across all parasite stages, thereby accentuating the imperative for novel anti-filarial medications characterized by enhanced prognostic attributes and minimized adverse reactions. A promising avenue involves targeting the microbial enzyme WBmDapE, pivotal in worm survival and intricately linked to the lysine biosynthetic pathway and peptidoglycan cell wall construction.

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About a decade ago, gallium oxide (GaO) was found to be a very attractive ultrawide-bandgap (4.6-4.9 eV) semiconductor for next-generation low-power devices.

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We aim to develop a low-cost silver nanoparticle (AgNP)-based delivery of AmB (AmB-AgNP) which can replace the costly AmBisome and toxic Fungizone formulation for applications against visceral leishmaniasis (VL) caused by the parasite Leishmania donovani (LD). Using different molar ratios of AmB and silver nitrate, we have identified a specific NP of ∼110 nm (zeta potential of -36.7 mV and PDI of 0.

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The development of multifunctional textiles can be achieved through coating techniques. Natural rubber latex (NRL) presents a promising bio-based coating material. Although, NRL can improve the mechanical properties, NRL alone does not provide multifunctionality.

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Background: With the increasing use of cosmetics, potential adverse effects such as allergic reactions and skin irritation warrant investigation. This study aims to assess cosmetic usage patterns, associated adverse effects, and awareness of cosmetovigilance among medical students. Despite the widespread use of cosmetics in India, region-specific data on adverse effects and cosmetovigilance awareness in Puducherry are limited.

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Background: Well-defined pre-cancerous stages help early detection of uterine cervical cancer by Pap smear or human papillomavirus (HPV) analysis. HPV induces atypical squamous cells of undetermined significance (ASCUS) which can progress to higher grade lesions depending on persistence of infection with High-risk human papillomavirus (HrHPV). The HrHPV prevalence and persistence after 18-36 months, associated risk factors for persistence among women with ASCUS, and the effect of persisting HrHPV in the cytological progression upto a period of seven years are analyzed.

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Millions of women worldwide have breast cancer, a common and possibly fatal illness according to WHO Reports. A genetic mutation usually causes breast adenocarcinomas. Only 5-10% of cancers are induced by genetic mutations that develop with age, and the "wear and tear" of general life causes 85-90% of breast cancers.

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Molecular docking is a structure-based computational technique that plays a major role in drug discovery. Molecular docking enhances the efficacy of determining the metabolic interaction between two molecules, i.e.

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Background And Objectives: Broad Autism Phenotype (BAP) refers to specific behaviors or minor deficits in social/communication skills not meeting the diagnostic criteria for autism spectrum disorders (ASDs). The BAP Questionnaire (BAPQ) measures aloof personality (AP), rigid personality (RP), and pragmatic language (PL) deficits of BAP. The study objective is to translate and validate BAPQ into Malayalam, a South Indian language, and to establish new cut-off scores for detecting BAP in the Indian population.

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Arid regions cover a large part of the Earth's surface and are at risk of increased agricultural activity and expected shifts in climate. Unfortunately, there is still a lack of comprehensive knowledge about the impact of land use on soil quality in these soils. Using a state factor approach, we studied the effects of different land use types on soil physico-chemical and biological characteristics in the Bhuj region of Kutch, Gujarat (India).

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Green synthesis of nanoparticles has become a significant area of research, driven by the demand for sustainable, economical, and environmentally friendly processes, particularly in biomedical applications. In this study, silver nanoparticles (AgNPs) were produced using 10 g of Couroupita guianensis flower extract through a straightforward and environmentally friendly method. The biosynthesized AgNPs were characterized using UV-Vis spectroscopy, XRD, FTIR, SEM, and EDS techniques, confirming their successful formation and structural properties.

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Tropical cyclones (TC) are dynamic atmospheric phenomena featuring extreme low-pressure systems and powerful winds, known for their devastating impacts on weather and the environment. The main purpose of this paper is to consider the subtle involvement of TCs in the air quality index (AQI), focusing on aspects related to the air quality before, during and after cyclones. This research employs multimodal methods, which include meteorological data and different satellite observations.

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Article Synopsis
  • Researchers designed stable pseudorotaxane complexes (PK@CAOPP and PR@CAOPP) to improve the targeted delivery of a chemotherapeutic drug specifically to cancer cells while avoiding normal cells.
  • The positively charged components in these complexes interact with negatively charged cell components, allowing them to localize in the mitochondrial membrane of cancer cells, where they trigger cell death through mechanisms like ROS generation.
  • The study demonstrates that these supramolecular adducts effectively induce cancer cell dysfunction without harming healthy cells, with promising results validated in mouse models.
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The biosynthesis of nanoparticles is a crucial research area aimed at developing innovative, cost-effective, and eco-friendly synthesis techniques for various applications. Herein, we synthesized copper oxide nanoparticles (CuNPs) using Couroupita guianensis flower extract via a simple green synthesis method. These green CuNPs demonstrate promising antimicrobial activity and anticancer activity against A549 nonsmall cell lung cancer (NSCLC) cells.

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Lignin, a valuable biomaterial having an array of exciting properties is increasingly favoured as a reinforcement material in the fabrication of green composites. Reinforcement in biopolymers like natural rubber (NR) using lignin nanoparticles (LNP) is considered a hotspot today. In this study, LNP synthesized via the homogenization method was incorporated into natural rubber latex (NRL) using probe sonication, and NR/Lignin nanocomposites (NR/LNP) were fabricated using latex dipping method.

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Introduction: Interproximal reduction (IPR) damages the caries protective superficial layer of the enamel, making the enamel surface prone to caries because of the increase in surface roughness. Remineralizing solutions can help in preventing these undesirable side effects. Therefore, this study aimed to compare the effect of nanohydroxyapatite (nHAp) and sodium fluoride (NaF) application on enamel remineralization after IPR and to evaluate changes in surface roughness, composition, and microhardness of the treated enamel.

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The online channel has affected many facets of an individual's identity, commercial, social policy, and culture, among others. It implies that discovering the topics on which these brief writings are focused, as well as examining the qualities of these short texts is critical. Another key issue that has been identified is the evaluation of newly discovered topics in terms of topic quality, which includes topic separation and coherence.

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Because of their propensity to build micellar nanostructures, amphiphilic block copolymers (ABCs) are an appropriate and unique toughening agent for epoxy systems individually on their own and in grafted form. The presence of epoxiphilic and phobic ends in ABCs is responsible for the self-assembly and the micellar structure. Nanofiller-grafted ABCs can effectively enhance the toughness of epoxy via the synergistic interaction of nanofillers and the ABCs.

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A unique fluorescent molecule (ND-S) was obtained from Eosin Y in two simple yet high yielding steps (1). ND-S has special metal ion sensing ability, such that it can selectively detect toxic Hg present in very low concentration in aqueous solutions in the presence of other competing metal ions. The host-guest complexation is ratiometric and is associated with significant increase in fluorescence during the process.

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Boron Nitride (h-BN) possesses unique qualities like increased thermal conductivity, non-toxic nature, and environmental friendliness; hence, it is a good reinforcing agent for chlorobutyl rubber (CIIR). Tannic acid (TA) holds excellent bio-functional properties and is considered as an exceptional bio-exfoliating agent. Hence, in this study, we have utilized the bio-exfoliating ability of TA to exfoliate h-BN and evaluate its efficiency in reinforcing the CIIR matrix.

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Retinal vessel segmentation is a critical process in the automated inquiry of fundus images to screen and diagnose diabetic retinopathy. It is a widespread complication of diabetes that causes sudden vision loss. Automated retinal vessel segmentation can help to detect these changes more accurately and quickly than manual evaluation by an ophthalmologist.

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