Working across religions, cultures, settings, and development: Protocol for wave 2 data collection with children and parents by the developing belief network.

The Developing Belief Network is a global research collaborative studying religious development in diverse social-cultural settings, with a focus on the intersection of cognitive mechanisms and cultural beliefs and practices in early and middle childhood. The current manuscript describes the study protocol for the network's second wave of data collection, which aims to further explore the development and diversity of religious cognition and behavior using a multi-time point approach. This protocol is designed to investigate three key research questions-how children represent and reason about religious and supernatural agents, how children represent and reason about religion as an aspect of social identity, and how religious and supernatural beliefs are transmitted within and between generations-via a set of eight tasks for children between the ages of 5 and 13 years and a survey completed by their parents/caregivers.

Characterization of the olive fly (Bactrocera oleae) microbiome across diverse geographic regions of Morocco.

The olive fruit fly (Bactrocera oleae) is a significant pest threatening olive production worldwide. Bactrocera oleae relies on symbiotic bacteria for nutrition, development, and adaptation to its environment. Among these, Candidatus Erwinia dacicola is the most dominant symbiont and plays a key role in the fly's physiology and ecological adaptation.

Manual therapy reduces pain, disability and oxidative stress in patients with chronic non-specific neck pain; a double-blind, randomized pilot study.

Objectives: Chronic nonspecific neck pain (CNNP) affects millions of people; nonetheless, several mechanistic details remain unknown. Oxidative stress (OS) is believed to be a contributing factor; however, its connection with manual therapy (MT), the current CNNP treatment, remains poorly investigated. Herein, the effects of low-velocity low-amplitude (LVLA) and high-velocity high-amplitude (HVLA) MT on pain relief, disability, and OS levels of CNNP patients are investigated.

DECODE: An open-source cloud-based platform for the noninvasive management of peripheral artery disease.

Background And Objective: Peripheral artery disease (PAD) is a progressive vascular condition affecting >237 million individuals worldwide. Accurate diagnosis and patient-specific treatment planning are critical but are often hindered by limited access to advanced imaging tools and real-time analytical support. This study presents DECODE, an open-source, cloud-based platform that integrates artificial intelligence, interactive 3D visualization, and computational modeling to improve the noninvasive management of PAD.

Slow movement in nursing education: a discussion paper based on an empty scoping review.

Aim: To map the existing evidence, identify gaps and critically discuss the Slow Movement concept as applied to nursing education.

Background: Nursing education is characterised by enormous pressure that may affect the quality of learning and students' stress levels. The Slow Movement approach suggests that education should be more reflective and focus on quality rather than speed.

Structural diversities and magnetic properties of azido- and dicyanamido-bridged coordination polymers with 4,5-diphenylimidazole as a terminal ligand.

With the aim of assessing the role and impact of pseudohalides on the molecular and supramolecular structures of copper(II)/heavily substituted imidazole complexes, the synthesis and characterization of the complexes {[Cu(N)(HL)]} (1), {[Cu{N(CN)}(HL)]·MeCO} (2·MeCO) and [Cu(NCO)(HL)]·MeCN (3·MeCN) have been carried out; HL is the 4,5-diphenylimidazole ligand. The organic molecule behaves as a monodentate ligand through the pyridine-type nitrogen atom of the imidazole ring. The 1D polymer 1 is made up of undulating {-Cu-(N)-Cu-(N)-} chains, with the HL ligands extending from both sides of the chains.

Lateral approach for total knee arthroplasty in patients with valgus deformity: A step-by-step surgical technique.

Background: The lateral approach in total knee arthroplasty (TKA) is indicated primarily for patients with valgus knee deformity, as it allows direct access to the lateral anatomy and systematic correction of associated pathologies.

Surgical Technique: This technique involves strategic lateral soft tissue releases, which improve exposure to the posterolateral corner, enhance tibial rotation, and support patellar alignment without compromising medial vascularity or requiring a tibial tubercle osteotomy for joint exposure. Critical steps in the lateral TKA approach include maintaining a capsular-synovial overlap and preserving the Hoffa fat pad for optimal joint closure, releasing the lateral soft-tissue structures, and using a contralateral tibial cutting guide for enhanced access and protection of the patellar tendon.

Infundibular origin of a duplicated anterior communicating artery mimicking an aneurysm.

The anterior communicating artery (AComA) is a common site of morphological variation and aneurysm formation. We report an unusual vascular anomaly identified during routine 3T magnetic resonance angiography (MRA) in a 67-year-old male under evaluation for cerebrovascular disease. Imaging revealed a duplicated AComA, with the first segment originating from an infundibular dilation of the right anterior cerebral artery (ACA).

Comparable outcomes and early revision rates between restricted and unrestricted functional knee positioning in robotic-assisted total knee arthroplasty for varus deformities ≥10°.

Purpose: Functional knee positioning (FKPos) in total knee arthroplasty (TKA) optimises outcomes by balancing individual anatomical and soft tissue characteristics. Managing marked varus deformity presents challenges in achieving balance when tibial alignment is restricted to 3° of varus, necessitating either medial soft tissue release or unrestricted tibial positioning. This study aims to compare restricted FKPos with medial soft tissue release to unrestricted FKPos without soft tissue release in patients with varus deformity ≥10°.

Machine learning tools for deciphering the regulatory logic of enhancers in health and disease.

Transcriptional enhancers are DNA regulatory elements that control the levels and spatiotemporal patterns of gene expression during development, homeostasis, and pathophysiological processes. Enhancer identification and characterization at the genome-wide scale rely on their structural characteristics, such as chromatin accessibility, binding of transcription factors and cofactors, activating histone modifications, 3D interactions with other regulatory elements, as well as functional characteristics measured by massively parallel reporter assays and sequence conservation approaches. Recently, machine learning approaches and particularly deep learning models (Enformer, BPNet, DeepSTARR, etc.

AI Methods Tailored to Influenza, RSV, HIV, and SARS-CoV-2: A Focused Review.

Artificial intelligence (AI) techniques-ranging from hybrid mechanistic-machine learning (ML) ensembles to gradient-boosted decision trees, support-vector machines, and deep neural networks-are transforming the management of seasonal influenza, respiratory syncytial virus (RSV), human immunodeficiency virus (HIV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Symptom-based triage models using eXtreme Gradient Boosting (XGBoost) and Random Forests, as well as imaging classifiers built on convolutional neural networks (CNNs), have improved diagnostic accuracy across respiratory infections. Transformer-based architectures and social media surveillance pipelines have enabled real-time monitoring of COVID-19.

Autonomous Exploration in Unknown Indoor 2D Environments Using Harmonic Fields and Monte Carlo Integration.

Efficient autonomous exploration in unknown obstacle cluttered environments with interior obstacles remains a challenging task for mobile robots. In this work, we present a novel exploration process for a non-holonomic agent exploring 2D spaces using onboard LiDAR sensing. The proposed method generates velocity commands based on the calculation of the solution of an elliptic Partial Differential Equation with Dirichlet boundary conditions.

Effect of pH, Temperature, Molecular Weight and Salt Concentration on the Structure and Hydration of Short Poly(,-dimethylaminoethyl methacrylate) Chains in Dilute Aqueous Solutions: A Combined Experimental and Molecular Dynamics Study.

We study the microstructural properties and state of hydration of aqueous low-molecular-weight poly(,-dimethylaminoethyl methacrylate) (PDMAEMA) solutions and their dependence on polymer concentration and pH by means of detailed atomistic Molecular Dynamics (MD) simulations and experiments. For infinitely dilute solutions with a degree of polymerization of = 30 at basic pH conditions, no temperature dependence is observed on the overall shape and state of hydration of the polyelectrolyte. This is supported by the experimental component of our work according to which the hydrodynamic radius, , does not change dramatically with temperature.

A Validation Study of the COPSOQ III Greek Questionnaire for Assessing Psychosocial Factors in the Workplace.

Background: Over the past two decades, the Copenhagen Psychosocial Questionnaire (COPSOQ) has been established as a valid instrument to measure psychosocial stress at work. Currently, the COPSOQ international network is responsible for monitoring and improving the COPSOQ. In 2019, a new questionnaire was published, and the Greek version is now being validated.

Sex Differences in Wheezing During the First Three Years of Life After Delivery via Caesarean Section.

Background: Emerging evidence suggests that delivery by caesarean section predisposes to wheezing in early childhood, but the effect may differ between boys and girls. Such sex-specific differences remain insufficiently explored to date, particularly considering the wide range of perinatal and antenatal confounding factors. In this study, we aimed to investigate sex-specific differences in the association between delivery by caesarean section and preschool wheezing.

Clinical Impact of CT-Based FFR in Everyday Cardiology: Bridging Computation and Decision-Making.

A revolutionary non-invasive method for the thorough evaluation of coronary artery disease (CAD) is fractional flow reserve (FFR) obtained from coronary computed tomography angiography (CCTA). Computed tomography-derived FFR (FFR) assesses both the anatomical and functional significance of coronary lesions simultaneously by utilizing sophisticated computational models, including computational fluid dynamics, machine learning (ML), and Artificial Intelligence (AI) methods. The technological development, validation research, clinical uses, and real-world constraints of FFR are compiled in this review.

Non-Coding RNAs in Neurodevelopmental Disorders-From Diagnostic Biomarkers to Therapeutic Targets: A Systematic Review.

: Neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD), are increasingly recognized as conditions arising from multifaceted interactions among genetic predisposition, environmental exposures, and epigenetic modifications. Among epigenetic mechanisms, non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and PIWI-interacting RNAs (piRNAs), have gained attention as pivotal regulators of gene expression during neurodevelopment. These RNA species do not encode proteins but modulate gene expression at transcriptional and post-transcriptional levels, thereby influencing neuronal differentiation, synaptogenesis, and plasticity.

The Role of Aldosterone and the Mineralocorticoid Receptor in Metabolic Dysfunction-Associated Steatotic Liver Disease.

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is one of the fastest-growing hepatic disorders worldwide. During its natural course, MASLD tends to progress from isolated steatosis of the liver to Metabolic Dysfunction-Associated Alcoholic Steatohepatitis (MASH), advanced fibrosis, and finally cirrhosis, with the risk of developing hepatocellular carcinoma (HCC). Although frequently related to overweight or obesity and other components of the metabolic syndrome (MS), MASLD can also be present in individuals without such risk factors.

Antimicrobial Activity of Greek Native Essential Oils Against O157:H7 and Antibiotic Resistance Strains Harboring Plasmid, , -1 and Genes.

Background/objectives: The rapid emergence of antibiotic-resistant in food and clinical environments necessitates new, clean-label antimicrobials. This study assessed eight Greek native essential oils-oregano, thyme, dittany, rosemary, peppermint, lavender, cistus and helichrysum-for activity against six genetically and phenotypically diverse strains (reference, , , -1, and O157:H7). We aimed to identify oils with broad-spectrum efficacy and clarify the chemical constituents responsible.

Antioxidant Nanohybrid Materials Derived via Olive Leaf Extract Incorporation in Layered Double Hydroxide: Preparation, Characterization, and Evaluation for Applications.

In this study, an innovative and sustainable strategy for the valorization of olive leaves, an underutilized agro-industrial byproduct, was developed through enzymatic-assisted aqueous extraction to produce a polyphenol-rich olive leaf extract (OLE). The extract contained notable concentrations of hydroxytyrosol (0.53 mg/L), luteolin-7-o-glucoside (0.

From Structure to Function: The Impact of EGFR and IGF-IR in 3D Breast Cancer Spheroids.

: Breast cancer, one of the most researched cancers in oncology, remains the primary cause of cancer-related mortality in women. Its biological complexity, which includes phenotypic, genetic, and microenvironmental aspects, makes modeling and treatment quite difficult. The need for more physiologically realistic models is highlighted by the comparison of two-dimensional (2D) cell cultures with 3D breast-cancer-derived spheroids, which discloses how important pathways such as epidermal growth factor receptor (EGFR) and insulin-like growth factor I receptor (IGF-IR) influence cell behavior and extracellular matrix (ECM) macromolecular expression.

SO disproportionation for a sulphur-based thermochemical cycle studied in an Raman batch reactor.

and Raman spectroscopy were used to study the iodide-catalysed SO disproportionation reaction at temperature of 118 °C and total pressures up to 9 bar. The disproportionation of SO is one of the three process steps constituting a solar-aided thermochemical sulphur-based cycle for producing unlimitedly storable sulphur capable for on-demand consumption. A suitably designed quartz-made batch reactor cell was used enabling a special containment of SO, capable for monitoring of the reaction progress in the liquid I/HO/SO phase as well as for quantitative monitoring of the SO pressure in the vapors thereof.

Cement or press-fit? Impact of patellar fixation technique on outcomes after primary TKA: a systematic review.

Introduction: The optimal fixation technique for patellar components in primary total knee arthroplasty (TKA); cemented versus press-fit, remains controversial. While early press-fit designs were associated with complications, second-generation implants with improved osseointegration features have renewed interest in cementless fixation.

Methods: This systematic review included studies comparing cemented and press-fit patellar fixation in primary TKA.

Investigation of irrigation fluid temperature variations caused by thulium fiber laser with various settings and comparison with Ho:YAG laser: An experimental study.

Introduction: Our experimental study aimed to evaluate the impact of four power settings with different energy and frequency combinations on the irrigation fluid temperature using the thulium fiber laser (TFL). In addition, we aimed to identify the differences between the Ho: YAG laser and TFL by direct comparison of the same power settings.

Material And Methods: All measurements were performed with a fluid volume fixed at 10 ml and an outflow rate at 10 ml/min.